Idarubicin
(JVHPTYWUBOQMBP-RVFAQHLVSA-N)
Structure
- SMILES
- O[C@H]1[C@@H](N)C[C@@H](O[C@H]1C)O[C@H]1C[C@@](O)(Cc2c1c(O)c1c(c2O)C(=O)c2c(C1=O)cccc2)C(=O)C.Cl
- Molecular Formula:
- C26H28ClNO9
- Molecular Weight:
- 533.955
- Log P:
- 2.5226
- Hydrogen Bond Acceptor:
- 10
- Hydrogen Bond Donor:
- 6
- TPSA:
- 176.61
- CAS Number(s):
- 57852-57-0
Synonym(s)
1.
Idarubicin
2.
4-Demethoxydaunorubicin
3.
4-Desmethoxydaunorubicin
4.
IMI-30
5.
Idarubicin Hydrochloride
6.
NSC-256439
7.
4 Demethoxydaunorubicin
8.
4 Desmethoxydaunorubicin
9.
Hydrochloride, Idarubicin
10.
IMI 30
11.
IMI30
12.
NSC 256439
13.
NSC256439
External Link(s)
| MeSH | D015255 |
| PubChem Compound | 636362 |
| ChEBI | 31686 |
| CHEMBL | CHEMBL1200976 |
| KEGG | dr:D01747 |
Adverse Drug Event(s)
| Name | Number of Reports | Reference(s) | Data Source | |
|---|---|---|---|---|
| 1 | Overdose | FAERS: 5 | US FAERS | |
| 2 | Drug administration error | FAERS: 4 | US FAERS | |
| 3 | Febrile Neutropenia | FAERS: 4 | US FAERS | |
| 4 | Hypotension | FAERS: 2 | US FAERS | |
| 5 | Neutropenic colitis | FAERS: 2 | US FAERS | |
| 6 | Vasculitis | FAERS: 2 | US FAERS | |
| 7 | Abdominal discomfort | FAERS: 1 | US FAERS | |
| 8 | Acute respiratory failure | FAERS: 1 | US FAERS | |
| 9 | Anuria | FAERS: 1 | US FAERS | |
| 10 | Atrial Fibrillation | FAERS: 1 | US FAERS | |
| 11 | Bradycardia | FAERS: 1 | US FAERS | |
| 12 | Cardiac Arrest | FAERS: 1 | US FAERS | |
| 13 | Chest Pain | FAERS: 1 | US FAERS | |
| 14 | Chest discomfort | FAERS: 1 | US FAERS | |
| 15 | Chills | FAERS: 1 | US FAERS | |
| 16 | Cyanosis | FAERS: 1 | US FAERS | |
| 17 | Disease Progression | FAERS: 1 | US FAERS | |
| 18 | Dizziness | FAERS: 1 | US FAERS | |
| 19 | Dysuria | FAERS: 1 | US FAERS | |
| 20 | Eosinophil percentage increased | FAERS: 1 | US FAERS | |
| 21 | Epstein-Barr virus associated lymphoma | FAERS: 1 | US FAERS | |
| 22 | Expired product administered | FAERS: 1 | US FAERS | |
| 23 | Feeling abnormal | FAERS: 1 | US FAERS | |
| 24 | Leukoencephalopathy | FAERS: 1 | US FAERS | |
| 25 | Leukopenia | FAERS: 1 | US FAERS | |
| 26 | Lymphocyte count increased | FAERS: 1 | US FAERS | |
| 27 | Malaise | FAERS: 1 | US FAERS | |
| 28 | Malignant neoplasm progression | FAERS: 1 | US FAERS | |
| 29 | Neutropenic sepsis | FAERS: 1 | US FAERS | |
| 30 | Pain | FAERS: 1 | US FAERS | |
| 31 | Pallor | FAERS: 1 | US FAERS | |
| 32 | Pericardial effusion | FAERS: 1 | US FAERS | |
| 33 | Product administration error | FAERS: 1 | US FAERS | |
| 34 | Pruritus | FAERS: 1 | US FAERS | |
| 35 | Pulmonary Fibrosis | FAERS: 1 | US FAERS | |
| 36 | Respiratory distress | FAERS: 1 | US FAERS | |
| 37 | Sepsis | FAERS: 1 | US FAERS | |
| 38 | Tremor | FAERS: 1 | US FAERS | |
| 39 | Ventricular Dysfunction | FAERS: 1 | US FAERS | |
| 40 | White blood cell count decreased | FAERS: 1 | US FAERS | |
| 41 | Wrong dose | FAERS: 1 | US FAERS |
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