Oxyphenbutazone
(HFHZKZSRXITVMK-UHFFFAOYSA-N)
Structure
- SMILES
- CCCCC1C(=O)N(N(C1=O)c1ccc(cc1)O)c1ccccc1
- Type(s)
- Approved; Withdrawn
- ATC code(s)
- M01AA03; M02AA04; S01BC02
- Molecular Formula:
- C19H20N2O3
- Molecular Weight:
- 324.374
- Log P:
- 3.6234
- Hydrogen Bond Acceptor:
- 5
- Hydrogen Bond Donor:
- 1
- TPSA:
- 60.85
- CAS Number(s):
- 129-20-4
Synonym(s)
1.
Oxyphenbutazone
2.
Hydroxyphenylbutazone
3.
Diflamil
4.
Oxyphenylbutazone
5.
Tanderil
External Link(s)
| MeSH | D010113 |
| PubChem Compound | 4641 |
| BindingDB | 200298 |
| ChEBI | 76258 |
| CHEMBL | CHEMBL1228 |
| DrugBank | DB03585 |
| DrugCentral | 2036 |
| KEGG | cpd:C19494 dr:D08324 |
| Therapeutic Target Database | D06ZPS |
Adverse Drug Event(s)
| Name | Number of Reports | Reference(s) | Data Source | |
|---|---|---|---|---|
| 1 | Abdominal Pain | Canada Vigilance: 1 | Canada Vigilance | |
| 2 | Agranulocytosis | Canada Vigilance: 2 | 3747087 | CTD Canada Vigilance |
| 3 | Amblyopia | Canada Vigilance: 1 | Canada Vigilance | |
| 4 | Asthenia | Canada Vigilance: 1 | Canada Vigilance | |
| 5 | Blepharitis | Canada Vigilance: 1 | Canada Vigilance | |
| 6 | Chills | Canada Vigilance: 1 | Canada Vigilance | |
| 7 | Dermatitis | Canada Vigilance: 4 | Canada Vigilance | |
| 8 | Dizziness | Canada Vigilance: 1 | Canada Vigilance | |
| 9 | Epistaxis | Canada Vigilance: 2 | Canada Vigilance | |
| 10 | Erythema Multiforme | Canada Vigilance: 1 | Canada Vigilance | |
| 11 | Erythema | Canada Vigilance: 4 | Canada Vigilance | |
| 12 | Eye irritation | Canada Vigilance: 1 | Canada Vigilance | |
| 13 | Gastritis | 2266080 | CTD | |
| 14 | Gingival Hemorrhage | 5079767 | CTD | |
| 15 | Gingivitis | Canada Vigilance: 1 | Canada Vigilance | |
| 16 | Glomerulonephritis | Canada Vigilance: 1 | Canada Vigilance | |
| 17 | Glossitis | Canada Vigilance: 1 | Canada Vigilance | |
| 18 | Headache | Canada Vigilance: 1 | Canada Vigilance | |
| 19 | Hepatitis | Canada Vigilance: 2 | Canada Vigilance | |
| 20 | Hypersensitivity | Canada Vigilance: 5 | Canada Vigilance | |
| 21 | Hyperthyroidism | Canada Vigilance: 1 | Canada Vigilance | |
| 22 | Kidney Cortex Necrosis | 972771 | CTD | |
| 23 | Leukopenia | Canada Vigilance: 1 | Canada Vigilance | |
| 24 | Lymphadenopathy | Canada Vigilance: 1 | Canada Vigilance | |
| 25 | Malaise | Canada Vigilance: 3 | Canada Vigilance | |
| 26 | Myalgia | Canada Vigilance: 1 | Canada Vigilance | |
| 27 | Mydriasis | Canada Vigilance: 1 | Canada Vigilance | |
| 28 | Myocarditis | Canada Vigilance: 1 | Canada Vigilance | |
| 29 | Nausea | Canada Vigilance: 2 | Canada Vigilance | |
| 30 | Pain | Canada Vigilance: 1 | Canada Vigilance | |
| 31 | Pancreatitis | 3832725 10484002 | CTD | |
| 32 | Pancytopenia | Canada Vigilance: 1 | Canada Vigilance | |
| 33 | Petechiae | Canada Vigilance: 1 | Canada Vigilance | |
| 34 | Proteinuria | Canada Vigilance: 1 | Canada Vigilance | |
| 35 | Pruritus | Canada Vigilance: 6 | Canada Vigilance | |
| 36 | Purpura | Canada Vigilance: 2 | 5079767 | CTD Canada Vigilance |
| 37 | Rash erythematous | Canada Vigilance: 1 | Canada Vigilance | |
| 38 | Sepsis | Canada Vigilance: 1 | Canada Vigilance | |
| 39 | Serum Sickness | Canada Vigilance: 1 | Canada Vigilance | |
| 40 | Sialadenitis | 3832725 | CTD | |
| 41 | Skin reaction | Canada Vigilance: 1 | Canada Vigilance | |
| 42 | Stevens-Johnson Syndrome | Canada Vigilance: 3 | Canada Vigilance | |
| 43 | Stomatitis | Canada Vigilance: 5 | Canada Vigilance | |
| 44 | Swelling | Canada Vigilance: 1 | Canada Vigilance | |
| 45 | Thrombocytopenia | Canada Vigilance: 3 | Canada Vigilance | |
| 46 | Thrombocytopenic purpura | Canada Vigilance: 1 | Canada Vigilance | |
| 47 | Urticaria | Canada Vigilance: 6 | Canada Vigilance | |
| 48 | Vertigo | Canada Vigilance: 1 | Canada Vigilance | |
| 49 | Vomiting | Canada Vigilance: 6 | Canada Vigilance |
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