MetaADEDB 2.0 @ LMMD
lacidipine
(GKQPCPXONLDCMU-CCEZHUSRSA-N)
Structure
SMILES
CCOC(=O)C1=C(C)NC(=C(C1c1ccccc1/C=C/C(=O)OC(C)(C)C)C(=O)OCC)C
Type(s)
Approved; Investigational
ATC code(s)
C08CA09
Molecular Formula:
C26H33NO6
Molecular Weight:
455.543
Log P:
4.7313
Hydrogen Bond Acceptor:
7
Hydrogen Bond Donor:
1
TPSA:
90.93
CAS Number(s):
103890-78-4
Synonym(s)
1.
lacidipine
2.
Caldine
3.
GR 43659X
4.
GR-43659X
5.
Lacimen
6.
Lacipil
7.
Motens
External Link(s)
MeSHC060285
PubChem Compound5311217
ChEBI135737
94480
CHEMBLCHEMBL1728809
CHEMBL460291
DrugBankDB09236
DrugCentral1532
KEGGdr:D04657
ZINC100015470
Adverse Drug Event(s)
NameNumber of ReportsReference(s)Data Source
1AcantholysisOFFSIDES
2AcidosisOFFSIDES
3Alanine Aminotransferase IncreasedOFFSIDES
4AlopeciaOFFSIDES
5AnisocoriaOFFSIDES
6Anticholinergic SyndromeOFFSIDES
7ArteriosclerosisOFFSIDES
8Arteriovenous fistula thrombosisOFFSIDES
9ArthropathyOFFSIDES
10AsphyxiaOFFSIDES
11AtaxiaOFFSIDES
12Atherosclerosis12417269CTD
13Blood creatine abnormalOFFSIDES
14Blood creatine phosphokinase increasedOFFSIDES
15Bulbar palsyOFFSIDES
16Burning sensationOFFSIDES
17Cardiac HypertrophyOFFSIDES
18Cerebral disorderOFFSIDES
19Conjunctival depositOFFSIDES
20Device malfunctionOFFSIDES
21DiabetesOFFSIDES
22DrowsinessOFFSIDES
23Duodenal ulcer perforationOFFSIDES
24Ejection Fraction DecreasedOFFSIDES
25Femoral artery occlusionOFFSIDES
26General physical health deteriorationOFFSIDES
27GranulocytosisOFFSIDES
28Hypertrophy9235228CTD
29Kidney FailureOFFSIDES
30Left ventricular end-diastolic pressure increasedOFFSIDES
31Livedo ReticularisOFFSIDES
32Mastication disorderOFFSIDES
33Motor retardationOFFSIDES
34Muscle WeaknessOFFSIDES
35Myocardial Infarction19296206CTD
36Myocardial fibrosisOFFSIDES
37OliguriaOFFSIDES
38OnycholysisOFFSIDES
39PemphigusOFFSIDES
40Peripheral arterial occlusive diseaseOFFSIDES
41PolyuriaOFFSIDES
42Psychiatric symptomOFFSIDES
43Retinal Vein OcclusionOFFSIDES
44RhabdomyolysisOFFSIDES
45SplenitisOFFSIDES
46Sudden deathOFFSIDES
47Tachycardia1691398CTD
48Transaminases increasedOFFSIDES
49Ventricular hypokinesiaOFFSIDES
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