MetaADEDB: Drug

MetaADEDB 2.0 @ LMMD

distigmine

(GJHSNEVFXQVOHR-UHFFFAOYSA-L)

Structure

SMILES: C[n+]1cccc(c1)OC(=O)N(CCCCCCN(C(=O)Oc1ccc[n+](c1)C)C)C.[Br-].[Br-]
Molecular Formula:: C22H32Br2N4O4
Molecular Weight:: 576.322
Log P:: -3.5346
Hydrogen Bond Acceptor:: 6
Hydrogen Bond Donor:: 0
TPSA:: 66.84
CAS Number(s):: 15876-67-2

Synonym(s)

distigmine

Ubretid

distigmine bromide

hexamarium

pyridinium, 3,3'-(1,6-hexanediylbis((methylimino)carbonyl)oxy)bis-1-methyl-, dibromide

External Link(s)

MeSH	C084645
PubChem Compound	27522
ChEBI	31512
CHEMBL	CHEMBL1098285
KEGG	dr:D01228

Adverse Drug Event(s)

	Name	Data Source
1	Acute myocardial infarction	OFFSIDES
2	Acute respiratory failure	OFFSIDES
3	Adenocarcinoma	OFFSIDES
4	Alanine Aminotransferase Increased	OFFSIDES
5	Altered state of consciousness	OFFSIDES
6	Anal abscess	OFFSIDES
7	Anastomotic stenosis	OFFSIDES
8	Apnea	OFFSIDES
9	Aspiration Pneumonia	OFFSIDES
10	Atrial tachycardia	OFFSIDES
11	B-lymphocyte count decreased	OFFSIDES
12	Basophil percentage increased	OFFSIDES
13	Benign Prostatic Hyperplasia	OFFSIDES
14	Bicytopenia	OFFSIDES
15	Blood albumin decreased	OFFSIDES
16	Blood alkaline phosphatase increased	OFFSIDES
17	Blood chloride decreased	OFFSIDES
18	Blood creatine phosphokinase increased	OFFSIDES
19	Blood lactate dehydrogenase increased	OFFSIDES
20	Blood sodium	OFFSIDES
21	Blood urea increased	OFFSIDES
22	Blood urine present	OFFSIDES
23	Cancer Pain	OFFSIDES
24	Cerebral ventricle dilatation	OFFSIDES
25	Dehydration	OFFSIDES
26	Depressed Level of Consciousness	OFFSIDES
27	Diet refusal	OFFSIDES
28	Dizziness	OFFSIDES
29	Drug administered at inappropriate site	OFFSIDES
30	Drug diversion	OFFSIDES
31	Dysgeusia	OFFSIDES
32	Eczema	OFFSIDES
33	Electroconvulsive Therapy	OFFSIDES
34	Erythema	OFFSIDES
35	Flank Pain	OFFSIDES
36	Formication	OFFSIDES
37	Gamma-Glutamyltransferase Increased	OFFSIDES
38	Granulocyte count decreased	OFFSIDES
39	Hemicephalalgia	OFFSIDES
40	Hemiparesis	OFFSIDES
41	Hemiplegia	OFFSIDES
42	Hypophagia	OFFSIDES
43	Hypoxia	OFFSIDES
44	Incorrect drug dosage form administered	OFFSIDES
45	Intentional drug misuse	OFFSIDES
46	Intercostal neuralgia	OFFSIDES
47	Klebsiella sepsis	OFFSIDES
48	Leukoencephalopathy	OFFSIDES
49	Leukopenia neonatal	OFFSIDES
50	Liver carcinoma ruptured	OFFSIDES
51	Lymphocyte percentage decreased	OFFSIDES
52	Multiple sclerosis relapse	OFFSIDES
53	Muscle Weakness	OFFSIDES
54	Myelitis	OFFSIDES
55	Nausea	OFFSIDES
56	Nocturia	OFFSIDES
57	Oculomucocutaneous syndrome	OFFSIDES
58	Optic Neuritis	OFFSIDES
59	Pemphigus	OFFSIDES
60	Perianal erythema	OFFSIDES
61	Peripheral arterial occlusive disease	OFFSIDES
62	Pneumothorax	OFFSIDES
63	Prescribed overdose	OFFSIDES
64	Psychiatric symptom	OFFSIDES
65	Pulmonary Infarction	OFFSIDES
66	Rhabdomyolysis	OFFSIDES
67	Sick Sinus Syndrome	OFFSIDES
68	Sinus bradycardia	OFFSIDES
69	Sputum retention	OFFSIDES
70	Syphilis	OFFSIDES
71	prostatitis	OFFSIDES

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