MetaADEDB 2.0 @ LMMD
AIC246
(FWYSMLBETOMXAG-QHCPKHFHSA-N)
Structure
SMILES
COc1cccc(c1)N1CCN(CC1)C1=Nc2c(F)cccc2[C@@H](N1c1cc(ccc1OC)C(F)(F)F)CC(=O)O
Type(s)
Approved; Investigational
ATC code(s)
J05AX18
Molecular Formula:
C29H28F4N4O4
Molecular Weight:
572.551
Log P:
5.2109
Hydrogen Bond Acceptor:
8
Hydrogen Bond Donor:
1
TPSA:
77.84
CAS Number(s):
917389-32-3
Synonym(s)
1.
AIC246
2.
letermovir
External Link(s)
MeSHC000588473
PubChem Compound45138674
CHEMBLCHEMBL1241951
DrugBankDB12070
DrugCentral5262
KEGGdr:D10801
Therapeutic Target DatabaseD0G8PA
ZINC100369359
Adverse Drug Event(s)
NameNumber of ReportsReference(s)Data Source
1Pathogen resistanceFAERS: 8US FAERS
2Adverse eventFAERS: 5US FAERS
3No adverse eventFAERS: 5US FAERS
4Product dose omissionFAERS: 5US FAERS
5treatment failureFAERS: 5US FAERS
6Drug resistanceFAERS: 3US FAERS
7Product use in unapproved indicationFAERS: 3US FAERS
8Product use issueFAERS: 3US FAERS
9Stem cell transplantFAERS: 3US FAERS
10Blood creatinine abnormalFAERS: 2US FAERS
11Blood urea increasedFAERS: 2US FAERS
12Circumstance or information capable of leading to medication errorFAERS: 2US FAERS
13Disease recurrenceFAERS: 2US FAERS
14Drug ineffectiveFAERS: 2US FAERS
15HeadacheFAERS: 2US FAERS
16Inappropriate schedule of product administrationFAERS: 2US FAERS
17Mental status changesFAERS: 2US FAERS
18SepsisFAERS: 2US FAERS
19ThrombocytopeniaFAERS: 2US FAERS
20Alanine Aminotransferase IncreasedFAERS: 1US FAERS
21AlopeciaFAERS: 1US FAERS
22Bacterial disease carrierFAERS: 1US FAERS
23Bacterial sepsisFAERS: 1US FAERS
24Blood alkaline phosphatase increasedFAERS: 1US FAERS
25Blood creatinine increasedFAERS: 1US FAERS
26Cytomegalovirus test positiveFAERS: 1US FAERS
27CytopeniaFAERS: 1US FAERS
28Disease ProgressionFAERS: 1US FAERS
29Drug dose omissionFAERS: 1US FAERS
30Drug effective for unapproved indicationFAERS: 1US FAERS
31FatigueFAERS: 1US FAERS
32Gastrointestinal toxicityFAERS: 1US FAERS
33General physical health deteriorationFAERS: 1US FAERS
34IleusFAERS: 1US FAERS
35LymphomaFAERS: 1US FAERS
36Medication ErrorFAERS: 1US FAERS
37NauseaFAERS: 1US FAERS
38Pneumatosis intestinalisFAERS: 1US FAERS
39PneumoniaFAERS: 1US FAERS
40ProctitisFAERS: 1US FAERS
41Product administered to patient of inappropriate ageFAERS: 1US FAERS
42Product availability issueFAERS: 1US FAERS
43Product blister packaging issueFAERS: 1US FAERS
44Product label confusionFAERS: 1US FAERS
45Product label issueFAERS: 1US FAERS
46Product packaging issueFAERS: 1US FAERS
47Respiratory FailureFAERS: 1US FAERS
48Septic ShockFAERS: 1US FAERS
49SinusitisFAERS: 1US FAERS
50StomatitisFAERS: 1US FAERS
51SwellingFAERS: 1US FAERS
52Toxicity to various agentsFAERS: 1US FAERS
53Viral load increasedFAERS: 1US FAERS
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