MetaADEDB 2.0 @ LMMD
Cycloserine
(DYDCUQKUCUHJBH-UWTATZPHSA-N)
Structure
SMILES
N[C@@H]1CONC1=O
Type(s)
Approved
ATC code(s)
J04AB01
Molecular Formula:
C3H6N2O2
Molecular Weight:
102.092
Log P:
-0.5958
Hydrogen Bond Acceptor:
4
Hydrogen Bond Donor:
2
TPSA:
64.35
CAS Number(s):
68-41-7; 339-72-0
Synonym(s)
1.
Cycloserine
2.
R-4-Amino-3-isoxazolidinone
3.
Seromycin
External Link(s)
MeSHD003523
PubChem Compound51670069
6234
BindingDB50103516
50038178
ChEBI74159
40009
CHEMBLCHEMBL771
DrugBankDB00260
DrugCentral759
IUPHAR/BPS Guide to PHARMACOLOGY9489
KEGGcpd:C08057
dr:D00877
Therapeutic Target DatabaseD04TMQ
D02WFK
D0G6RT
ZINC34676245
Adverse Drug Event(s)
NameNumber of ReportsReference(s)Data Source
1AmnesiaFAERS: 18981605CTD
US FAERS
2Completed SuicideFAERS: 1US FAERS
3Anxiety Disorders12078031
18179785		CTD
4AstheniaCanada Vigilance: 1Canada Vigilance
5AtaxiaCanada Vigilance: 1Canada Vigilance
6Bradycardia3683766CTD
7Brain Diseases4261138
18484995		CTD
8Bromosulphthalein test abnormalCanada Vigilance: 2Canada Vigilance
9Chemical and Drug Induced Liver Injury4800729CTD
10Cocaine-Related Disorders19144966
20014913		CTD
11DermatitisSIDER
12Disorders of Excessive Somnolence18484995CTD
13DisorientationSIDER
14DizzinessCanada Vigilance: 2Canada Vigilance
15DrowsinessSIDER
16DysarthriaSIDER
17Feeling abnormalSIDER
18HeadacheCanada Vigilance: 1Canada Vigilance
SIDER
19HepatotoxicityCanada Vigilance: 1Canada Vigilance
20HyperreflexiaSIDER
21HypersensitivitySIDER
22Hypotension3683766CTD
23Memory Disorders10727642CTD
24Mental disorders5729888
5783221
18283911		CTD
25Mental impairmentCanada Vigilance: 1Canada Vigilance
26Myoclonus943260CTD
27ParesisSIDER
28PruritusCanada Vigilance: 1Canada Vigilance
29Psychoses, Substance-Induced5729888
18283911		CTD
30Seizures5262029
18283911		CTD
31SomnolenceSIDER
32Substance Withdrawal Syndrome8747757CTD
33SyncopeCanada Vigilance: 1Canada Vigilance
34TremorSIDER
35Tuberculosis, Multidrug-Resistant8399888
15182146
18283911		CTD
36Tuberculosis, Pulmonary5271994
8399888		CTD
37Tuberculosis5271987
16933231		CTD
38VertigoCanada Vigilance: 1Canada Vigilance
SIDER
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