andrographolide
(BOJKULTULYSRAS-OTESTREVSA-N)
Structure
- SMILES
- OC[C@]1(C)[C@H](O)CC[C@@]2([C@@H]1CCC(=C)[C@H]2C/C=C/1\[C@H](O)COC1=O)C
- Type(s)
- Investigational
- Molecular Formula:
- C20H30O5
- Molecular Weight:
- 350.449
- Log P:
- 1.9626
- Hydrogen Bond Acceptor:
- 5
- Hydrogen Bond Donor:
- 3
- TPSA:
- 86.99
- CAS Number(s):
- 5508-58-7; 869807-57-8
Synonym(s)
1.
andrographolide
2.
17-hydro-9-dehydro-andrographolide
3.
isoandrographolide
External Link(s)
| MeSH | C030419 |
| PubChem Compound | 5318517 |
| BindingDB | 50084419 |
| ChEBI | 65408 |
| CHEMBL | CHEMBL186141 |
| DrugBank | DB05767 |
| IUPHAR/BPS Guide to PHARMACOLOGY | 9675 |
| KEGG | cpd:C20214 |
| Therapeutic Target Database | D04VIS |
| ZINC | 3881797 |
Adverse Drug Event(s)
| Name | Number of Reports | Reference(s) | Data Source | |
|---|---|---|---|---|
| 1 | Carcinoma | 19426720 | CTD | |
| 2 | Chemical and Drug Induced Liver Injury | 25110055 26485141 | CTD | |
| 3 | Colorectal Neoplasms | 19426720 24563380 | CTD | |
| 4 | Inflammation | 31128153 | CTD | |
| 5 | Liver Cirrhosis, Experimental | 29355602 | CTD | |
| 6 | Liver Cirrhosis | 20946909 | CTD | |
| 7 | Liver Neoplasms, Experimental | 19679627 | CTD | |
| 8 | Lung diseases | 31128153 | CTD |
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