proxymetacaine
(BFUUJUGQJUTPAF-UHFFFAOYSA-N)
Structure
- SMILES
- CCCOc1ccc(cc1N)C(=O)OCCN(CC)CC.Cl
- Molecular Formula:
- C16H27ClN2O3
- Molecular Weight:
- 330.850
- Log P:
- 3.9394
- Hydrogen Bond Acceptor:
- 5
- Hydrogen Bond Donor:
- 2
- TPSA:
- 64.79
- CAS Number(s):
- 5875-06-9
Synonym(s)
1.
proxymetacaine
2.
2-(diethylamino)ethyl 3-amino-4-propoxybenzoate
3.
2-(diethylamino)ethyl 3-amino-4-propoxybenzoate monohydrochloride
4.
AK-Taine
5.
Alcaine
6.
Chibro-Kerakain
7.
Kainair
8.
Kéracaine
9.
Minims Proxymetacaine Hydrochloride
10.
Ocu-Caine
11.
Ophthaine
12.
Ophthetic
13.
Parcaine
14.
Proparakain-POS
15.
benzoic acid, 3-amino-4-propoxy-, 2-(diethylamino)ethyl ester
16.
benzoic acid, 3-amino-4-propoxy-, 2-(diethylamino)ethyl ester, monohydrochloride*benzoic acid, 3-amino-4-propoxy-, 2-(diethylamino)ethyl ester, monohydrochloride
17.
proparacaine
18.
proparacaine HCl
19.
proparacaine hydrochloride
20.
proxymetacaine hydrochloride
21.
proxymetacaine monohydrochloride
22.
proxymethacaine
External Link(s)
| MeSH | C005717 |
| PubChem Compound | 517321 22169 |
| CHEMBL | CHEMBL1200464 |
| KEGG | dr:D02098 |
Adverse Drug Event(s)
| Name | Number of Reports | Reference(s) | Data Source | |
|---|---|---|---|---|
| 1 | Drug abuse | FAERS: 9 | US FAERS | |
| 2 | Corneal epithelium defect | FAERS: 7 | US FAERS | |
| 3 | Eye pain | FAERS: 7 | US FAERS | |
| 4 | Dizziness | FAERS: 5 | US FAERS | |
| 5 | Headache | FAERS: 5 | US FAERS | |
| 6 | Eye irritation | FAERS: 4 | US FAERS | |
| 7 | Asthenia | FAERS: 3 | US FAERS | |
| 8 | Hypopyon | FAERS: 3 | US FAERS | |
| 9 | Keratitis | FAERS: 3 Canada Vigilance: 3 | Canada Vigilance US FAERS | |
| 10 | Keratopathy | FAERS: 3 | US FAERS | |
| 11 | Photophobia | FAERS: 3 | US FAERS | |
| 12 | Presyncope | FAERS: 3 | US FAERS | |
| 13 | Corneal Opacity | FAERS: 2 | US FAERS | |
| 14 | Corneal Scar | FAERS: 2 | US FAERS | |
| 15 | Drug ineffective | FAERS: 2 | US FAERS | |
| 16 | Drug screen positive | FAERS: 2 | US FAERS | |
| 17 | Mydriasis | FAERS: 2 | US FAERS | |
| 18 | Nausea | FAERS: 2 Canada Vigilance: 1 | Canada Vigilance US FAERS | |
| 19 | Acanthamoeba Keratitis | FAERS: 1 | US FAERS | |
| 20 | Accidental exposure to product | FAERS: 1 | US FAERS | |
| 21 | Blindness | FAERS: 1 | US FAERS | |
| 22 | Bradycardia | FAERS: 1 Canada Vigilance: 1 | Canada Vigilance US FAERS | |
| 23 | Burning sensation | FAERS: 1 | US FAERS | |
| 24 | Cold sweat | FAERS: 1 | US FAERS | |
| 25 | Corneal Endothelial Cell Loss | FAERS: 1 | US FAERS | |
| 26 | Corneal abscess | FAERS: 1 | US FAERS | |
| 27 | Corneal lesion | FAERS: 1 | US FAERS | |
| 28 | Corneal thinning | FAERS: 1 | US FAERS | |
| 29 | Dermatitis | FAERS: 1 | US FAERS | |
| 30 | Erythema | FAERS: 1 | US FAERS | |
| 31 | Eyelid infection | FAERS: 1 | US FAERS | |
| 32 | Eyelids pruritus | FAERS: 1 | US FAERS | |
| 33 | Feeling abnormal | FAERS: 1 | US FAERS | |
| 34 | Foreign body sensation in eyes | FAERS: 1 | US FAERS | |
| 35 | Hyperacusis | FAERS: 1 | US FAERS | |
| 36 | Hypersensitivity | FAERS: 1 | US FAERS | |
| 37 | Incorrect dose administered | FAERS: 1 | US FAERS | |
| 38 | Infectious crystalline keratopathy | FAERS: 1 | US FAERS | |
| 39 | Muscle Spasticity | FAERS: 1 | US FAERS | |
| 40 | Nervousness | FAERS: 1 | US FAERS | |
| 41 | Ocular discomfort | FAERS: 1 | US FAERS | |
| 42 | Pain | FAERS: 1 | US FAERS | |
| 43 | Pallor | FAERS: 1 Canada Vigilance: 1 | Canada Vigilance US FAERS | |
| 44 | Product container seal issue | FAERS: 1 | US FAERS | |
| 45 | Product dropper issue | FAERS: 1 | US FAERS | |
| 46 | Product label issue | FAERS: 1 | US FAERS | |
| 47 | Product prescribing error | FAERS: 1 | US FAERS | |
| 48 | Product quality issue | FAERS: 1 | US FAERS | |
| 49 | Product use in unapproved indication | FAERS: 1 | US FAERS | |
| 50 | Punctate keratitis | FAERS: 1 | US FAERS | |
| 51 | Rash erythematous | FAERS: 1 | US FAERS | |
| 52 | Skin reaction | FAERS: 1 | US FAERS | |
| 53 | Staphylococcus test positive | FAERS: 1 | US FAERS | |
| 54 | Swelling | FAERS: 1 | US FAERS | |
| 55 | Syncope | FAERS: 1 Canada Vigilance: 2 | Canada Vigilance US FAERS | |
| 56 | Toxic anterior segment syndrome | FAERS: 1 | US FAERS | |
| 57 | Visual Impairment | FAERS: 1 Canada Vigilance: 1 | Canada Vigilance US FAERS | |
| 58 | Vomiting | FAERS: 1 | US FAERS | |
| 59 | Chest discomfort | Canada Vigilance: 1 | Canada Vigilance | |
| 60 | Hypotension | Canada Vigilance: 3 | Canada Vigilance |
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