Terlipressin
(BENFXAYNYRLAIU-QSVFAHTRSA-N)
Structure
- SMILES
- NCCCC[C@@H](C(=O)NCC(=O)N)NC(=O)[C@@H]1CCCN1C(=O)[C@@H]1CSSC[C@H](NC(=O)CNC(=O)CNC(=O)CN)C(=O)N[C@@H](Cc2ccc(cc2)O)C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N1)CC(=O)N)CCC(=O)N)Cc1ccccc1
- Type(s)
- Approved; Investigational
- ATC code(s)
- H01BA04
- Molecular Formula:
- C52H74N16O15S2
- Molecular Weight:
- 1227.370
- Log P:
- 0.0574
- Hydrogen Bond Acceptor:
- 33
- Hydrogen Bond Donor:
- 16
- TPSA:
- 563.45
- CAS Number(s):
- 14636-12-5
Synonym(s)
1.
Terlipressin
2.
Glipressin
3.
Gly-Gly-Gly-8-Lys-vasopressin
4.
Glycylpressin
5.
Glypressin
6.
N-(alpha)-glycyl-glycyl-glycyl-8-lysine vasopressin
7.
Remestyp
8.
TGLVP
9.
Terlypressin
10.
Triglycyl Lysine Vasopressin
11.
Triglycyl-(8-lysine)vasopressin
12.
Triglycylvasopressin
13.
Vasopressin, tri-Gly-8-Lys-
14.
Gly Gly Gly 8 Lys vasopressin
15.
tri-Gly-8-Lys- Vasopressin
External Link(s)
| MeSH | D000077585 |
| PubChem Compound | 72081 |
| ChEBI | 135905 |
| CHEMBL | CHEMBL2135460 |
| DrugBank | DB02638 |
| DrugCentral | 2967 |
| KEGG | dr:D06672 |
| Therapeutic Target Database | D0P4VX |
Adverse Drug Event(s)
| Name | Number of Reports | Reference(s) | Data Source | |
|---|---|---|---|---|
| 1 | Abdominal Cramps | SIDER | ||
| 2 | Abdominal Pain | SIDER | ||
| 3 | Acute Coronary Syndrome | SIDER | ||
| 4 | Atrial Fibrillation | SIDER | ||
| 5 | Blood creatinine decreased | SIDER | ||
| 6 | Bradycardia | SIDER | ||
| 7 | Chest Pain | SIDER | ||
| 8 | Cyanosis | 17125115 | CTD SIDER | |
| 9 | Fluid overload | SIDER | ||
| 10 | Gout | 9799074 | CTD | |
| 11 | Headache | SIDER | ||
| 12 | Hepatorenal Syndrome | 11051385 | CTD | |
| 13 | Hypotension | CTD | ||
| 14 | Injection site necrosis | SIDER | ||
| 15 | Malnutrition | SIDER | ||
| 16 | Mesenteric vascular insufficiency | SIDER | ||
| 17 | Myocardial Infarction | SIDER | ||
| 18 | Nausea | SIDER | ||
| 19 | Pallor facial | SIDER | ||
| 20 | Pallor | SIDER | ||
| 21 | Pregnancy | SIDER | ||
| 22 | Respiratory Failure | SIDER | ||
| 23 | Respiratory distress | SIDER | ||
| 24 | Skin necrosis | SIDER | ||
| 25 | Tachycardia | SIDER | ||
| 26 | Ventricular Fibrillation | SIDER | ||
| 27 | Vomiting | SIDER | ||
| 28 | nervous system disorder | SIDER |
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