Cilengitide
(AMLYAMJWYAIXIA-VWNVYAMZSA-N)
Structure
- SMILES
- OC(=O)C[C@@H]1NC(=O)CNC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@@H](N(C(=O)[C@H](NC1=O)Cc1ccccc1)C)C(C)C
- Type(s)
- Investigational
- Molecular Formula:
- C27H40N8O7
- Molecular Weight:
- 588.656
- Log P:
- 0.4783
- Hydrogen Bond Acceptor:
- 15
- Hydrogen Bond Donor:
- 7
- TPSA:
- 238.41
- CAS Number(s):
- 188968-51-6
Synonym(s)
1.
Cilengitide
2.
EMD 121974
3.
EMD121974
4.
cyclic-Arg-Gly-Asp-D-Phe(N-methyl)Val
5.
cyclo(RGDf-N(Me)V)
6.
cyclo(arginyl-glycyl-formylaspartyl-N-methylvalyl)
External Link(s)
Adverse Drug Event(s)
| Name | Number of Reports | Reference(s) | Data Source | |
|---|---|---|---|---|
| 1 | Leukopenia | FAERS: 1 | US FAERS | |
| 2 | Thrombocytopenia | FAERS: 1 | US FAERS | |
| 3 | Apathy | OFFSIDES | ||
| 4 | Arteriosclerosis | OFFSIDES | ||
| 5 | Blood sodium | OFFSIDES | ||
| 6 | Cytolytic hepatitis | OFFSIDES | ||
| 7 | Deafness | OFFSIDES | ||
| 8 | Duodenal Ulcer | OFFSIDES | ||
| 9 | Epistaxis | OFFSIDES | ||
| 10 | Fatigue | OFFSIDES | ||
| 11 | Gastrointestinal infection | OFFSIDES | ||
| 12 | Glioblastoma | 19239041 | CTD | |
| 13 | Hepatotoxicity | OFFSIDES | ||
| 14 | Leukopenia neonatal | OFFSIDES | ||
| 15 | Pancreatic enzymes increased | OFFSIDES | ||
| 16 | Prostatic Neoplasms | 16729916 | CTD | |
| 17 | Pulmonary artery thrombosis | OFFSIDES | ||
| 18 | Retinal Artery Occlusion | OFFSIDES | ||
| 19 | Stevens-Johnson Syndrome | OFFSIDES | ||
| 20 | Sudden death | OFFSIDES | ||
| 21 | Superficial Thrombophlebitis | OFFSIDES |
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