MetaADEDB 2.0 @ LMMD
Guanethidine
(ACGDKVXYNVEAGU-UHFFFAOYSA-N)
Structure
SMILES
NC(=NCCN1CCCCCCC1)N
Type(s)
Approved
ATC code(s)
C02CC02; C02LF01; S01EX01
Molecular Formula:
C10H22N4
Molecular Weight:
198.308
Log P:
1.8644
Hydrogen Bond Acceptor:
4
Hydrogen Bond Donor:
2
TPSA:
67.64
CAS Number(s):
55-65-2; 60-02-6
Synonym(s)
1.
Guanethidine
2.
((2-Hexahydro-1(2H)-azocinyl)ethyl)guanidine
3.
Guanethidine Monosulfate
4.
Guanethidine Sulfate
5.
Guanethidine Sulfate (1:1)
6.
Guanethidine Sulfate (1:2)
7.
Guanethidine Sulfate (2:1)
8.
Guanethidine Sulfate (2:1), 14C-Labeled
9.
Ismelin
10.
Isobarin
11.
Octadine
12.
Oktadin
13.
Monosulfate, Guanethidine
14.
Sulfate, Guanethidine
External Link(s)
MeSHD006145
PubChem Compound3518
ChEBI5557
CHEMBLCHEMBL765
DrugBankDB01170
DrugCentral1342
IUPHAR/BPS Guide to PHARMACOLOGY7194
KEGGdr:D02237
dr:D08030
cpd:C07036
Therapeutic Target DatabaseD0N3PE
ZINC1530648
Adverse Drug Event(s)
NameNumber of ReportsReference(s)Data Source
1Angina PectorisFAERS: 2
Canada Vigilance: 2		Canada Vigilance
US FAERS
2Chest discomfortFAERS: 2US FAERS
3Limb discomfortFAERS: 2US FAERS
4Myocardial InfarctionFAERS: 262901
12906986		CTD
US FAERS
5Stent occlusionFAERS: 1US FAERS
6Abdominal PainCanada Vigilance: 1Canada Vigilance
7Abdominal discomfortCanada Vigilance: 2Canada Vigilance
8AstheniaCanada Vigilance: 4Canada Vigilance
9Atrioventricular Block5638475CTD
10BradycardiaCanada Vigilance: 4541046
4085539		CTD
Canada Vigilance
11Cerebral Infarction62901CTD
12ConstipationCanada Vigilance: 1Canada Vigilance
13Depressive disorder4431808CTD
14Diarrhea6850722CTD
15DizzinessCanada Vigilance: 5Canada Vigilance
16Drug ineffectiveCanada Vigilance: 5Canada Vigilance
17Duodenal UlcerCanada Vigilance: 1Canada Vigilance
18DysgeusiaCanada Vigilance: 3Canada Vigilance
19Dyspnea5676415CTD
20Erectile dysfunction4607314CTD
21ErythemaCanada Vigilance: 1Canada Vigilance
22FatigueCanada Vigilance: 25676415CTD
Canada Vigilance
23FlushingCanada Vigilance: 1Canada Vigilance
24Gastrointestinal sounds abnormalCanada Vigilance: 1Canada Vigilance
25Glaucoma352088CTD
26HeadacheCanada Vigilance: 15676415CTD
Canada Vigilance
27Hyperalgesia12727271CTD
28HypersensitivityCanada Vigilance: 1Canada Vigilance
29Hypotension, Orthostatic

View details

62901
127594
1665057
4607314
4726158
7070101
 		CTD
30HypotensionCanada Vigilance: 2

View details

341940
981091
2862255
3688391
4085539
10549407
 		CTD
Canada Vigilance
31Injection site inflammationCanada Vigilance: 1Canada Vigilance
32Injection site painCanada Vigilance: 1Canada Vigilance
33LethargyCanada Vigilance: 1Canada Vigilance
34Muscle Weakness4607314CTD
35Musculoskeletal stiffnessCanada Vigilance: 1Canada Vigilance
36NauseaCanada Vigilance: 1Canada Vigilance
37Nerve Degeneration438995
4628152		CTD
38PainCanada Vigilance: 816099101
16563475		CTD
Canada Vigilance
39PruritusCanada Vigilance: 4Canada Vigilance
40Reflex Sympathetic Dystrophy6666530CTD
41Sinus Arrest, Cardiac541046CTD
42SomnolenceCanada Vigilance: 1Canada Vigilance
43Spasm623942CTD
44Substance Withdrawal Syndrome6391206CTD
45Suicide attemptCanada Vigilance: 1Canada Vigilance
46SyncopeCanada Vigilance: 2Canada Vigilance
47Tachycardia, Ventricular6057135CTD
48Throat irritationCanada Vigilance: 1Canada Vigilance
49TinnitusCanada Vigilance: 1Canada Vigilance
50VomitingCanada Vigilance: 2Canada Vigilance
Powered by :

Page last updated at 2020-05-25 10:01:57 (Asia/Shanghai) | You are visitor No. 120295

Copyright © 2019-2020 Laboratory of Molecular Modeling and Design, Shanghai Key Laboratory of New Drug Design, School of Pharmacy, East China University of Science and Technology. All rights reserved.