cevimeline
(ZSTLCHCDLIUXJE-UHFFFAOYSA-N)
Structure
- SMILES
- CC1SCC2(O1)CN1CCC2CC1.CC1SCC2(O1)CN1CCC2CC1.O.Cl.Cl
- Molecular Formula:
- C20H38Cl2N2O3S2
- Molecular Weight:
- 489.563
- Log P:
- 4.5359
- Hydrogen Bond Acceptor:
- 7
- Hydrogen Bond Donor:
- 3
- TPSA:
- 84.77
- CAS Number(s):
- 153504-70-2
Synonym(s)
1.
cevimeline
2.
2-methyspiro(1,3-oxathiolane-5,3)quinuclidine
3.
AF 102B
4.
AF 102B, (cis-(+))-isomer
5.
AF 102B, (trans)-isomer
6.
AF-102B
7.
AF102B
8.
Evoxac
9.
FKS 508
10.
FKS-508
11.
SNI 2011
12.
SNI-2011
13.
cevimeline hydrochloride
External Link(s)
Adverse Drug Event(s)
| Name | Number of Reports | Reference(s) | Data Source | |
|---|---|---|---|---|
| 1 | Unevaluable event | FAERS: 22 | US FAERS | |
| 2 | Drug ineffective | FAERS: 19 | US FAERS | |
| 3 | Malaise | FAERS: 6 | US FAERS | |
| 4 | Dehydration | FAERS: 4 | US FAERS | |
| 5 | No adverse event | FAERS: 4 | US FAERS | |
| 6 | Nausea | FAERS: 3 | US FAERS | |
| 7 | Blood creatine phosphokinase increased | FAERS: 2 | US FAERS | |
| 8 | Blood creatinine increased | FAERS: 2 | US FAERS | |
| 9 | Depressed Level of Consciousness | FAERS: 2 | US FAERS | |
| 10 | Incorrect dose administered | FAERS: 2 | US FAERS | |
| 11 | Oliguria | FAERS: 2 | US FAERS | |
| 12 | Pneumatosis intestinalis | FAERS: 2 | US FAERS | |
| 13 | Alopecia | FAERS: 1 | US FAERS | |
| 14 | Altered visual depth perception | FAERS: 1 | US FAERS | |
| 15 | Angle Closure Glaucoma | FAERS: 1 | US FAERS | |
| 16 | Anxiety | FAERS: 1 | US FAERS | |
| 17 | Asthenia | FAERS: 1 | US FAERS | |
| 18 | Atrial Fibrillation | FAERS: 1 | US FAERS | |
| 19 | Atrioventricular Block | FAERS: 1 | US FAERS | |
| 20 | Blindness | FAERS: 1 | US FAERS | |
| 21 | Cholelithiasis | FAERS: 1 | US FAERS | |
| 22 | Chorea | FAERS: 1 | US FAERS | |
| 23 | Chromaturia | FAERS: 1 | US FAERS | |
| 24 | Crying | FAERS: 1 | US FAERS | |
| 25 | Discomfort | FAERS: 1 | US FAERS | |
| 26 | Dizziness | FAERS: 1 | US FAERS | |
| 27 | Drug dose omission | FAERS: 1 | US FAERS | |
| 28 | Economic problem | FAERS: 1 | US FAERS | |
| 29 | Eye pain | FAERS: 1 | US FAERS | |
| 30 | Eye prosthesis insertion | FAERS: 1 | US FAERS | |
| 31 | Flushing | FAERS: 1 | US FAERS | |
| 32 | Headache | FAERS: 1 | US FAERS | |
| 33 | Hypotension | FAERS: 1 | US FAERS | |
| 34 | Incoherent | FAERS: 1 | US FAERS | |
| 35 | Inflammation | FAERS: 1 | US FAERS | |
| 36 | Musculoskeletal Pain | FAERS: 1 | US FAERS | |
| 37 | Myalgia | FAERS: 1 | US FAERS | |
| 38 | Neck Pain | FAERS: 1 | US FAERS | |
| 39 | Neuralgia | FAERS: 1 | US FAERS | |
| 40 | Nocturia | FAERS: 1 | US FAERS | |
| 41 | Ocular Rosacea | FAERS: 1 | US FAERS | |
| 42 | Parotitis | FAERS: 1 | US FAERS | |
| 43 | Poor quality sleep | FAERS: 1 | US FAERS | |
| 44 | Product administration error | FAERS: 1 | US FAERS | |
| 45 | Product substitution issue | FAERS: 1 | US FAERS | |
| 46 | Quality of life decreased | FAERS: 1 | US FAERS | |
| 47 | Rash erythematous | FAERS: 1 | US FAERS | |
| 48 | Saliva altered | FAERS: 1 | US FAERS | |
| 49 | Septic Shock | FAERS: 1 | US FAERS | |
| 50 | Sjogren's Syndrome | FAERS: 1 | US FAERS | |
| 51 | Stevens-Johnson Syndrome | FAERS: 1 | US FAERS | |
| 52 | Stomatitis | FAERS: 1 | US FAERS | |
| 53 | Syncope | FAERS: 1 | US FAERS | |
| 54 | Terminal state | FAERS: 1 | US FAERS | |
| 55 | Thirst | FAERS: 1 | US FAERS | |
| 56 | Toothache | FAERS: 1 | US FAERS | |
| 57 | Transaminases increased | FAERS: 1 | US FAERS | |
| 58 | Tremor | FAERS: 1 | US FAERS | |
| 59 | Urinary Incontinence | FAERS: 1 | US FAERS | |
| 60 | Vomiting | FAERS: 1 | US FAERS | |
| 61 | nervous system disorder | FAERS: 1 | US FAERS |
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