MetaADEDB 2.0 @ LMMD
alogliptin
(ZSBOMTDTBDDKMP-OAHLLOKOSA-N)
Structure
SMILES
N#Cc1ccccc1Cn1c(cc(=O)n(c1=O)C)N1CCC[C@H](C1)N
Type(s)
Approved
ATC code(s)
A10BD09; A10BD13; A10BH04
Molecular Formula:
C18H21N5O2
Molecular Weight:
339.392
Log P:
1.1598
Hydrogen Bond Acceptor:
7
Hydrogen Bond Donor:
1
TPSA:
97.05
CAS Number(s):
850649-61-5
Synonym(s)
1.
alogliptin
2.
2-((6-((3R)-3-aminopiperidin-1-yl)-3-methyl-2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)methyl) benzonitrile
3.
SYR 322
4.
SYR-322
5.
SYR322
6.
nesina
External Link(s)
MeSHC520853
PubChem Compound11450633
BindingDB16285
ChEBI72323
CHEMBLCHEMBL376359
DrugBankDB06203
DrugCentral4340
IUPHAR/BPS Guide to PHARMACOLOGY6319
KEGGdr:D06553
Therapeutic Target DatabaseD04ACW
D0Q7YI
D0NJ5H
ZINC14961096
Adverse Drug Event(s)
NameNumber of ReportsReference(s)Data Source
1PancreatitisFAERS: 5SIDER
US FAERS
2PruritusFAERS: 4US FAERS
3Chest PainFAERS: 3US FAERS
4Drug ineffectiveFAERS: 3US FAERS
5Back PainFAERS: 2US FAERS
6Blood glucose increasedFAERS: 2US FAERS
7Creatinine renal clearance decreasedFAERS: 2US FAERS
8EczemaFAERS: 2US FAERS
9ErythemaFAERS: 2US FAERS
10HeadacheFAERS: 2SIDER
US FAERS
11InfectionFAERS: 2US FAERS
12MalaiseFAERS: 2US FAERS
13NauseaFAERS: 2US FAERS
14UrticariaFAERS: 2SIDER
US FAERS
15VomitingFAERS: 2US FAERS
16Abdominal PainFAERS: 1US FAERS
17Adverse eventFAERS: 1US FAERS
18Altered state of consciousnessFAERS: 1US FAERS
19AmnesiaFAERS: 1US FAERS
20AnxietyFAERS: 1US FAERS
21Blood magnesium decreasedFAERS: 1US FAERS
22BronchitisFAERS: 1US FAERS
23Burning sensationFAERS: 1US FAERS
24Diabetic NephropathyFAERS: 1US FAERS
25Diabetic RetinopathyFAERS: 1US FAERS
26DiplopiaFAERS: 1US FAERS
27Dropped head syndromeFAERS: 1US FAERS
28DyspepsiaFAERS: 1US FAERS
29Erythema MultiformeFAERS: 1SIDER
US FAERS
30Eye painFAERS: 1US FAERS
31FatigueFAERS: 1US FAERS
32Feeling abnormalFAERS: 1US FAERS
33Lip swellingFAERS: 1US FAERS
34Lung consolidationFAERS: 1US FAERS
35MYELODYSPLASTIC SYNDROMEFAERS: 1US FAERS
36NervousnessFAERS: 1US FAERS
37PainFAERS: 1US FAERS
38PalpitationsFAERS: 1US FAERS
39Pancreatic carcinomaFAERS: 1US FAERS
40Peripheral swellingFAERS: 1US FAERS
41PharyngitisFAERS: 1US FAERS
42PneumoniaFAERS: 1US FAERS
43Product dose omissionFAERS: 1US FAERS
44RetchingFAERS: 1US FAERS
45Rotator cuff syndromeFAERS: 1US FAERS
46Skin UlcerFAERS: 1US FAERS
47SomnolenceFAERS: 1US FAERS
48TremorFAERS: 1US FAERS
49UlcerFAERS: 1US FAERS
50jaundiceFAERS: 1US FAERS
51Anaphylactic shockSIDER
52AngioedemaSIDER
53DermatitisSIDER
54Diabetes MellitusSIDER
55HypersensitivitySIDER
56NasopharyngitisSIDER
57Serum SicknessSIDER
58Stevens-Johnson Syndrome25811541CTD
SIDER
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