gadobutrol
(ZPDFIIGFYAHNSK-CTHHTMFSSA-K)
Structure
- SMILES
- OC[C@H]([C@H](N1CCN(CCN(CCN(CC1)CC(=O)[O-])CC(=O)[O-])CC(=O)[O-])CO)O.[Gd+3]
- Molecular Formula:
- C18H31GdN4O9
- Molecular Weight:
- 604.710
- Log P:
- -8.0766
- Hydrogen Bond Acceptor:
- 13
- Hydrogen Bond Donor:
- 3
- TPSA:
- 194.04
- CAS Number(s):
- 138071-82-6
Synonym(s)
1.
gadobutrol
2.
Gadovist
3.
Gd-DO3A-butriol
4.
gadolinium-DO3A-butriol
External Link(s)
Adverse Drug Event(s)
| Name | Number of Reports | Reference(s) | Data Source | |
|---|---|---|---|---|
| 1 | Urticaria | FAERS: 5 | US FAERS | |
| 2 | Contrast media deposition | FAERS: 4 | US FAERS | |
| 3 | Hypotension | FAERS: 2 | US FAERS | |
| 4 | Nausea | FAERS: 2 | US FAERS | |
| 5 | Pruritus | FAERS: 2 | US FAERS | |
| 6 | Vomiting | FAERS: 2 | US FAERS | |
| 7 | Altered state of consciousness | FAERS: 1 | US FAERS | |
| 8 | Asthenia | FAERS: 1 | US FAERS | |
| 9 | Cerebral Infarction | FAERS: 1 | US FAERS | |
| 10 | Cerebrovascular accident | FAERS: 1 | US FAERS | |
| 11 | Contrast media allergy | FAERS: 1 | US FAERS | |
| 12 | Contrast media reaction | FAERS: 1 | US FAERS | |
| 13 | Dizziness | FAERS: 1 | US FAERS | |
| 14 | Hypoxia | FAERS: 1 | US FAERS | |
| 15 | Incorrect route of product administration | FAERS: 1 | US FAERS | |
| 16 | Oxygen saturation abnormal | FAERS: 1 | US FAERS | |
| 17 | Palpitations | FAERS: 1 | US FAERS | |
| 18 | Product use in unapproved indication | FAERS: 1 | US FAERS | |
| 19 | Respiratory Failure | FAERS: 1 | US FAERS | |
| 20 | Septic Shock | FAERS: 1 | US FAERS | |
| 21 | Throat irritation | FAERS: 1 | US FAERS |
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