MetaADEDB 2.0 @ LMMD
lovastatin-niacin combination
(YVPOVOVZCOOSBQ-AXHZAXLDSA-N)
Structure
SMILES
OC(=O)c1cccnc1.CC[C@@H](C(=O)O[C@H]1C[C@@H](C)C=C2[C@H]1[C@@H](CC[C@@H]1C[C@@H](O)CC(=O)O1)[C@H](C=C2)C)C
Molecular Formula:
C30H41NO7
Molecular Weight:
527.649
Log P:
4.9753
Hydrogen Bond Acceptor:
8
Hydrogen Bond Donor:
2
TPSA:
123.02
CAS Number(s):
365453-26-5
Synonym(s)
1.
lovastatin-niacin combination
2.
Advicor
External Link(s)
MeSHC451780
PubChem Compound151176
Adverse Drug Event(s)
NameNumber of ReportsReference(s)Data Source
1FlushingFAERS: 107US FAERS
2MyalgiaFAERS: 20US FAERS
3DizzinessFAERS: 18OFFSIDES
US FAERS
4PruritusFAERS: 17US FAERS
5NauseaFAERS: 10OFFSIDES
US FAERS
6ArthralgiaFAERS: 8US FAERS
7ChillsFAERS: 8US FAERS
8Drug ineffectiveFAERS: 6US FAERS
9ErythemaFAERS: 6OFFSIDES
US FAERS
10HeadacheFAERS: 6US FAERS
11Medication residueFAERS: 5OFFSIDES
US FAERS
12PainFAERS: 5US FAERS
13VomitingFAERS: 5US FAERS
14AstheniaFAERS: 4US FAERS
15Blood glucose increasedFAERS: 4US FAERS
16Burning sensationFAERS: 4OFFSIDES
US FAERS
17UrticariaFAERS: 4US FAERS
18jaundiceFAERS: 4US FAERS
19AmnesiaFAERS: 3OFFSIDES
US FAERS
20Chest PainFAERS: 3OFFSIDES
US FAERS
21ChromaturiaFAERS: 3OFFSIDES
US FAERS
22FatigueFAERS: 3US FAERS
23Hepatic infiltration eosinophilicFAERS: 3OFFSIDES
US FAERS
24Hepatic necrosisFAERS: 3US FAERS
25Hepatitis C antibody positiveFAERS: 3OFFSIDES
US FAERS
26HepatitisFAERS: 3US FAERS
27PalpitationsFAERS: 3US FAERS
28Abdominal discomfortFAERS: 2US FAERS
29AnxietyFAERS: 2OFFSIDES
US FAERS
30ApathyFAERS: 2US FAERS
31Back PainFAERS: 2US FAERS
32Blood creatine phosphokinase increasedFAERS: 2US FAERS
33Bone painFAERS: 2OFFSIDES
US FAERS
34Cerebrovascular accidentFAERS: 2US FAERS
35Feeling abnormalFAERS: 2US FAERS
36HypersensitivityFAERS: 2US FAERS
37Joint swellingFAERS: 2US FAERS
38MalaiseFAERS: 2US FAERS
39RhabdomyolysisFAERS: 2OFFSIDES
US FAERS
40Sexual DysfunctionFAERS: 2US FAERS
41SyncopeFAERS: 2US FAERS
42TachycardiaFAERS: 2US FAERS
43Therapeutic response unexpectedFAERS: 2US FAERS
44TremorFAERS: 2US FAERS
45Abdominal PainFAERS: 1US FAERS
46Activities of daily living impairedFAERS: 1OFFSIDES
US FAERS
47Alanine Aminotransferase IncreasedFAERS: 1US FAERS
48Amyotrophic Lateral SclerosisFAERS: 1US FAERS
49ArthritisFAERS: 1US FAERS
50BlepharospasmFAERS: 1OFFSIDES
US FAERS
51Blood cholesterol increasedFAERS: 1US FAERS
52CataractFAERS: 1US FAERS
53ConstipationFAERS: 1US FAERS
54Dental cariesFAERS: 1US FAERS
55DiplopiaFAERS: 1OFFSIDES
US FAERS
56DiscomfortFAERS: 1US FAERS
57Dry skinFAERS: 1US FAERS
58DysgeusiaFAERS: 1US FAERS
59DyspepsiaFAERS: 1OFFSIDES
US FAERS
60Educational problemFAERS: 1OFFSIDES
US FAERS
61EosinophiliaFAERS: 1US FAERS
62Erectile dysfunctionFAERS: 1OFFSIDES
US FAERS
63Eye irritationFAERS: 1US FAERS
64Eye painFAERS: 1US FAERS
65Feeling jitteryFAERS: 1US FAERS
66FlatulenceFAERS: 1US FAERS
67GastritisFAERS: 1US FAERS
68Hepatitis CFAERS: 1US FAERS
69HungerFAERS: 1US FAERS
70HypoventilationFAERS: 1US FAERS
71Iatrogenic infectionFAERS: 1US FAERS
72Impaired work abilityFAERS: 1US FAERS
73Inadequate analgesiaFAERS: 1US FAERS
74InfluenzaFAERS: 1US FAERS
75Intervertebral disc compressionFAERS: 1OFFSIDES
US FAERS
76LaryngitisFAERS: 1US FAERS
77Low density lipoprotein increasedFAERS: 1US FAERS
78Miscarriage of partnerFAERS: 1US FAERS
79Musculoskeletal PainFAERS: 1US FAERS
80Neck PainFAERS: 1US FAERS
81Night sweatsFAERS: 1US FAERS
82Nipple painFAERS: 1US FAERS
83PallorFAERS: 1US FAERS
84Performance status decreasedFAERS: 1US FAERS
85Pharmaceutical product complaintFAERS: 1US FAERS
86PlasmacytosisFAERS: 1US FAERS
87Poor quality sleepFAERS: 1US FAERS
88Product contamination microbialFAERS: 1US FAERS
89Skin hypertrophyFAERS: 1US FAERS
90Stress at workFAERS: 1OFFSIDES
US FAERS
91SwellingFAERS: 1US FAERS
92ThrombosisFAERS: 1US FAERS
93TinnitusFAERS: 1US FAERS
94UlcerFAERS: 1US FAERS
95Unevaluable eventFAERS: 1OFFSIDES
US FAERS
96Urine output increasedFAERS: 1US FAERS
97Visual ImpairmentFAERS: 1US FAERS
98Visual disturbanceFAERS: 1US FAERS
99Vulvovaginal mycotic infectionFAERS: 1US FAERS
100Walking aid userFAERS: 1US FAERS
101Wheelchair userFAERS: 1US FAERS
102White blood cell count decreasedFAERS: 1US FAERS
103Wrong technique in drug usage processFAERS: 1US FAERS
104Abdominal AbscessOFFSIDES
105Acid refluxOFFSIDES
106Acute myocardial infarctionOFFSIDES
107Alcoholic IntoxicationOFFSIDES
108AnalgesiaOFFSIDES
109AnhedoniaOFFSIDES
110Ankle FractureOFFSIDES
111Atrial tachycardiaOFFSIDES
112Blood GlucoseOFFSIDES
113Blood albumin decreasedOFFSIDES
114Blood urea increasedOFFSIDES
115Bone erosionOFFSIDES
116Bone lesionOFFSIDES
117BruxismOFFSIDES
118Cardioactive drug level increasedOFFSIDES
119Cerebral atrophyOFFSIDES
120Circumstance or information capable of leading to medication errorOFFSIDES
121Colonic StenosisOFFSIDES
122Colonic fistulaOFFSIDES
123ConfabulationOFFSIDES
124Congenital tricuspid valve incompetenceOFFSIDES
125CraniotomyOFFSIDES
126DeafnessOFFSIDES
127DehydrationOFFSIDES
128DemyelinationOFFSIDES
129Dental cleaningOFFSIDES
130Dental prosthesis placementOFFSIDES
131Diabetic RetinopathyOFFSIDES
132DiverticulitisOFFSIDES
133DiverticulosisOFFSIDES
134Drug dispensing errorOFFSIDES
135Drug toxicityOFFSIDES
136Duodenal UlcerOFFSIDES
137DuodenitisOFFSIDES
138DysphoniaOFFSIDES
139Economic problemOFFSIDES
140Ejection Fraction DecreasedOFFSIDES
141Electrocardiogram ST segment abnormalOFFSIDES
142Emotional distressOFFSIDES
143Esophageal StenosisOFFSIDES
144Fatty LiverOFFSIDES
145Femoral arterial stenosisOFFSIDES
146FormicationOFFSIDES
147Gastric pH decreasedOFFSIDES
148Grip strengthOFFSIDES
149Hay feverOFFSIDES
150HepatosplenomegalyOFFSIDES
151HypokinesiaOFFSIDES
152IncontinenceOFFSIDES
153Increased upper airway secretionOFFSIDES
154InfectionOFFSIDES
155Intermittent ClaudicationOFFSIDES
156Intestinal ObstructionOFFSIDES
157Intestinal PerforationOFFSIDES
158Large intestine perforationOFFSIDES
159Left Ventricular HypertrophyOFFSIDES
160Loose toothOFFSIDES
161LymphedemaOFFSIDES
162Multiple allergiesOFFSIDES
163Musculoskeletal discomfortOFFSIDES
164Nasal discomfortOFFSIDES
165NephrolithiasisOFFSIDES
166NocturiaOFFSIDES
167OrthopneaOFFSIDES
168ParaplegiaOFFSIDES
169Partner stressOFFSIDES
170PeritonitisOFFSIDES
171Physical disabilityOFFSIDES
172PlasmapheresisOFFSIDES
173Protein total decreasedOFFSIDES
174Pulmonary HypertensionOFFSIDES
175Pulmonary arterial pressure increasedOFFSIDES
176Pulmonary congestionOFFSIDES
177RectoceleOFFSIDES
178Respiratory FailureOFFSIDES
179ScotomaOFFSIDES
180Septic ShockOFFSIDES
181SinusitisOFFSIDES
182SnoringOFFSIDES
183Sputum culture positiveOFFSIDES
184Superficial ThrombophlebitisOFFSIDES
185Supraventricular tachycardiaOFFSIDES
186Toe operationOFFSIDES
187Urinary bladder polypOFFSIDES
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