nilutamide
(XWXYUMMDTVBTOU-UHFFFAOYSA-N)
Structure
- SMILES
- O=C1NC(C(=O)N1c1ccc(c(c1)C(F)(F)F)[N+](=O)[O-])(C)C
- Type(s)
- Approved; Investigational
- ATC code(s)
- L02BB02
- Molecular Formula:
- C12H10F3N3O4
- Molecular Weight:
- 317.221
- Log P:
- 3.3654
- Hydrogen Bond Acceptor:
- 4
- Hydrogen Bond Donor:
- 1
- TPSA:
- 95.23
- CAS Number(s):
- 63612-50-0
Synonym(s)
1.
nilutamide
2.
5,5-dimethyl-3-(4-nitro-3-(trifluoromethyl)phenyl)- 2,4-imidazolidinedione
3.
Anandron
4.
Nilandron
5.
RU 23908
6.
RU 23908-10
7.
RU-23908
External Link(s)
Adverse Drug Event(s)
| Name | Number of Reports | Reference(s) | Data Source | |
|---|---|---|---|---|
| 1 | Chest discomfort | FAERS: 2 | US FAERS | |
| 2 | Dizziness | FAERS: 2 | SIDER US FAERS | |
| 3 | Peripheral swelling | FAERS: 2 | US FAERS | |
| 4 | Antidepressant drug level increased | FAERS: 1 | US FAERS | |
| 5 | Back Pain | FAERS: 1 | SIDER US FAERS | |
| 6 | Cholestasis | FAERS: 1 | US FAERS | |
| 7 | Dysphonia | FAERS: 1 | US FAERS | |
| 8 | Fatigue | FAERS: 1 | US FAERS | |
| 9 | Lethargy | FAERS: 1 | US FAERS | |
| 10 | Somnolence | FAERS: 1 | US FAERS | |
| 11 | Syncope | FAERS: 1 | SIDER US FAERS | |
| 12 | Thrombocytopenia | FAERS: 1 | US FAERS | |
| 13 | Unevaluable event | FAERS: 1 | US FAERS | |
| 14 | Urinary Retention | FAERS: 1 | US FAERS | |
| 15 | nervous system disorder | FAERS: 1 | US FAERS | |
| 16 | Abdominal Pain | SIDER | ||
| 17 | Abnormal vision | SIDER | ||
| 18 | Agranulocytosis | Canada Vigilance: 1 | Canada Vigilance | |
| 19 | Alanine Aminotransferase Increased | SIDER | ||
| 20 | Alcohol Intolerance | SIDER | ||
| 21 | Alopecia | SIDER | ||
| 22 | Angina Pectoris | SIDER | ||
| 23 | Anorexia | SIDER | ||
| 24 | Arthritis | SIDER | ||
| 25 | Arthropathy | Canada Vigilance: 1 | Canada Vigilance | |
| 26 | Aspartate Aminotransferase Increased | SIDER | ||
| 27 | Asthenia | SIDER | ||
| 28 | Atelectasis | Canada Vigilance: 1 | Canada Vigilance | |
| 29 | Blood alkaline phosphatase increased | SIDER | ||
| 30 | Blood creatinine increased | SIDER | ||
| 31 | Blood urea increased | SIDER | ||
| 32 | Bone pain | SIDER | ||
| 33 | Bronchiectasis | Canada Vigilance: 1 | Canada Vigilance | |
| 34 | Cardiac Hypertrophy | Canada Vigilance: 1 | Canada Vigilance | |
| 35 | Cataract | SIDER | ||
| 36 | Chest Pain | SIDER | ||
| 37 | Chromatopsia | SIDER | ||
| 38 | Constipation | SIDER | ||
| 39 | Creatinine increased | SIDER | ||
| 40 | Dermatitis | SIDER | ||
| 41 | Discomfort | SIDER | ||
| 42 | Disturbance in sexual arousal | SIDER | ||
| 43 | Dry skin | SIDER | ||
| 44 | Dyspepsia | SIDER | ||
| 45 | Erectile dysfunction | SIDER | ||
| 46 | Feeling abnormal | SIDER | ||
| 47 | Gastrointestinal Pain | SIDER | ||
| 48 | Guillain-Barre Syndrome | Canada Vigilance: 1 | Canada Vigilance | |
| 49 | Haptoglobin increased | SIDER | ||
| 50 | Headache | SIDER | ||
| 51 | Influenza | SIDER | ||
| 52 | Leukopenia | SIDER | ||
| 53 | Malaise | SIDER | ||
| 54 | Mitral Valve Stenosis | Canada Vigilance: 1 | Canada Vigilance | |
| 55 | Myalgia | Canada Vigilance: 1 | Canada Vigilance | |
| 56 | Nausea | SIDER | ||
| 57 | Nervousness | SIDER | ||
| 58 | Nocturia | SIDER | ||
| 59 | Oropharyngeal pain | Canada Vigilance: 1 | Canada Vigilance | |
| 60 | Pain | SIDER | ||
| 61 | Pericardial effusion | Canada Vigilance: 1 | Canada Vigilance | |
| 62 | Photophobia | SIDER | ||
| 63 | Pneumonia | SIDER | ||
| 64 | Pneumonitis | Canada Vigilance: 1 | Canada Vigilance | |
| 65 | Prostatic Neoplasms | 21846139 | CTD | |
| 66 | Pruritus | SIDER | ||
| 67 | Pulmonary Embolism | Canada Vigilance: 1 | Canada Vigilance | |
| 68 | Pulmonary Fibrosis | Canada Vigilance: 1 | Canada Vigilance | |
| 69 | Pulmonary Hypertension | Canada Vigilance: 1 | Canada Vigilance | |
| 70 | Pulmonary congestion | Canada Vigilance: 1 | Canada Vigilance | |
| 71 | Rhinitis | SIDER | ||
| 72 | Shock | SIDER | ||
| 73 | Sweating | SIDER | ||
| 74 | Tension | SIDER | ||
| 75 | Urinary tract infection | SIDER | ||
| 76 | Visual Impairment | SIDER | ||
| 77 | Visual disturbance | SIDER | ||
| 78 | Vomiting | SIDER | ||
| 79 | Weight decreased | SIDER |
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