MetaADEDB 2.0 @ LMMD
pazufloxacin
(XAGMUUZPGZWTRP-ZETCQYMHSA-N)
Structure
SMILES
OC(=O)c1cn2[C@@H](C)COc3c2c(c1=O)cc(c3C1(N)CC1)F
Type(s)
Investigational
ATC code(s)
J01MA18
Molecular Formula:
C16H15FN2O4
Molecular Weight:
318.300
Log P:
2.4403
Hydrogen Bond Acceptor:
6
Hydrogen Bond Donor:
2
TPSA:
94.55
CAS Number(s):
127045-41-4; 127046-18-8
Synonym(s)
1.
pazufloxacin
2.
10-(1-aminocyclopropyl)-9-fluoro-3-methyl-7-oxo-2,3-dihydro-7H-pyrido(1,2,3-d,e)(1,4)benzoxazinecarboxylic acid
3.
T 3761
4.
T-3761
External Link(s)
MeSHC078052
PubChem Compound65957
40466872
BindingDB50248017
ChEBI94700
CHEMBLCHEMBL240163
DrugBankDB11774
DrugCentral2070
KEGGdr:D01153
ZINC3779726
Adverse Drug Event(s)
NameNumber of ReportsReference(s)Data Source
1Acute respiratory failureOFFSIDES
2Altered state of consciousnessOFFSIDES
3Band neutrophil percentage increasedOFFSIDES
4Blood alkaline phosphatase increasedOFFSIDES
5Blood creatine increasedOFFSIDES
6Blood lactate dehydrogenase increasedOFFSIDES
7Blood sodium increasedOFFSIDES
8Blood thrombin increasedOFFSIDES
9Blood uric acid decreasedOFFSIDES
10Brain natriuretic peptide increasedOFFSIDES
11Clostridium colitisOFFSIDES
12Concomitant disease progressionOFFSIDES
13CystOFFSIDES
14Depressed Level of ConsciousnessOFFSIDES
15Diastolic dysfunctionOFFSIDES
16Disseminated Intravascular CoagulationOFFSIDES
17EczemaOFFSIDES
18EpidermolysisOFFSIDES
19ErythropeniaOFFSIDES
20Febrile NeutropeniaOFFSIDES
21Gamma-Glutamyltransferase IncreasedOFFSIDES
22Gamma-glutamyltransferase abnormalOFFSIDES
23General physical health deteriorationOFFSIDES
24Hepatic infiltration eosinophilicOFFSIDES
25HyperventilationOFFSIDES
26Immunosuppressant drug levelOFFSIDES
27Incisional herniaOFFSIDES
28Leukopenia neonatalOFFSIDES
29Lymphocyte percentage decreasedOFFSIDES
30Malignant neoplasm progressionOFFSIDES
31Neutrophil count decreasedOFFSIDES
32Oculomucocutaneous syndromeOFFSIDES
33Platelet TransfusionOFFSIDES
34Pulmonary congestionOFFSIDES
35Pyoderma GangrenosumOFFSIDES
36Red blood cell schistocytes presentOFFSIDES
37Respiratory FailureOFFSIDES
38Retroperitoneal lymphadenopathyOFFSIDES
39Seizures12199111CTD
40Sick Sinus SyndromeOFFSIDES
41Sudden deathOFFSIDES
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