Amantadine
(WOLHOYHSEKDWQH-UHFFFAOYSA-N)
Structure
- SMILES
- NC12CC3CC(C2)CC(C1)C3.Cl
- Molecular Formula:
- C10H18ClN
- Molecular Weight:
- 187.710
- Log P:
- 3.4162
- Hydrogen Bond Acceptor:
- 1
- Hydrogen Bond Donor:
- 2
- TPSA:
- 26.02
- CAS Number(s):
- 665-66-7
Synonym(s)
1.
Amantadine
2.
1-Aminoadamantane
3.
Adamantylamine
4.
Adekin
5.
Aman
6.
Amanta
7.
Amanta-HCI-AZU
8.
Amanta-Sulfate-AZU
9.
Amantadin AL
10.
Amantadin AZU
11.
Amantadin Stada
12.
Amantadin-neuraxpharm
13.
Amantadin-ratiopharm
14.
Amantadina Juventus
15.
Amantadina Llorente
16.
Amantadine Hydrochloride
17.
Amantadine Sulfate
18.
Amixx
19.
Cerebramed
20.
Endantadine
21.
Gen-Amantadine
22.
Infecto-Flu
23.
Infex
24.
Mantadix
25.
Midantan
26.
PMS-Amantadine
27.
Symadine
28.
Symmetrel
29.
Viregyt
30.
Wiregyt
31.
tregor
32.
1 Aminoadamantane
33.
AL, Amantadin
34.
AZU, Amantadin
35.
Amanta HCI AZU
36.
Amanta Sulfate AZU
37.
AmantaHCIAZU
38.
AmantaSulfateAZU
39.
Amantadin neuraxpharm
40.
Amantadin ratiopharm
41.
Amantadinneuraxpharm
42.
Amantadinratiopharm
43.
Gen Amantadine
44.
GenAmantadine
45.
Hydrochloride, Amantadine
46.
Infecto Flu
47.
InfectoFlu
48.
Juventus, Amantadina
49.
Llorente, Amantadina
50.
PMS Amantadine
51.
PMSAmantadine
52.
Stada, Amantadin
53.
Sulfate, Amantadine
External Link(s)
| MeSH | D000547 |
| PubChem Compound | 517422 64150 19031614 |
| ChEBI | 2619 |
| CHEMBL | CHEMBL1569 CHEMBL1255870 |
| KEGG | cpd:C07939 dr:D00777 |
Adverse Drug Event(s)
| Name | Number of Reports | Reference(s) | Data Source | |
|---|---|---|---|---|
| 1 | Drug ineffective | FAERS: 8 Canada Vigilance: 1 | Canada Vigilance US FAERS | |
| 2 | Agitation | FAERS: 6 | US FAERS | |
| 3 | Toxicity to various agents | FAERS: 6 | US FAERS | |
| 4 | Dizziness | FAERS: 5 | US FAERS | |
| 5 | Myoclonus | FAERS: 5 | US FAERS | |
| 6 | Disorientation | FAERS: 4 | US FAERS | |
| 7 | Fatigue | FAERS: 4 | US FAERS | |
| 8 | Livedo Reticularis | FAERS: 4 | US FAERS | |
| 9 | Medication Error | FAERS: 4 | US FAERS | |
| 10 | Nausea | FAERS: 4 | US FAERS | |
| 11 | Cerebral Infarction | FAERS: 3 | US FAERS | |
| 12 | Delirium | FAERS: 3 | US FAERS | |
| 13 | Drug level increased | FAERS: 3 | US FAERS | |
| 14 | Headache | FAERS: 3 | US FAERS | |
| 15 | Mental status changes | FAERS: 3 | US FAERS | |
| 16 | Mydriasis | FAERS: 3 | US FAERS | |
| 17 | Overdose | FAERS: 3 | US FAERS | |
| 18 | Status Epilepticus | FAERS: 3 | US FAERS | |
| 19 | Vomiting | FAERS: 3 | US FAERS | |
| 20 | Asthenia | FAERS: 2 | US FAERS | |
| 21 | Bedridden | FAERS: 2 | US FAERS | |
| 22 | Blindness | FAERS: 2 | US FAERS | |
| 23 | Completed Suicide | FAERS: 2 | US FAERS | |
| 24 | Dementia | FAERS: 2 | US FAERS | |
| 25 | Drug toxicity | FAERS: 2 | US FAERS | |
| 26 | Drug withdrawal syndrome | FAERS: 2 | US FAERS | |
| 27 | Dysarthria | FAERS: 2 | US FAERS | |
| 28 | Dystonia | FAERS: 2 | US FAERS | |
| 29 | Incorrect dose administered | FAERS: 2 | US FAERS | |
| 30 | Intentional self-injury | FAERS: 2 | US FAERS | |
| 31 | Peripheral swelling | FAERS: 2 | US FAERS | |
| 32 | Product substitution issue | FAERS: 2 | US FAERS | |
| 33 | Skin lesion | FAERS: 2 | US FAERS | |
| 34 | Thrombosis | FAERS: 2 | US FAERS | |
| 35 | Accidental drug intake by child | FAERS: 1 | US FAERS | |
| 36 | Acute psychosis | FAERS: 1 | US FAERS | |
| 37 | Altered state of consciousness | FAERS: 1 | US FAERS | |
| 38 | Anxiety | FAERS: 1 | US FAERS | |
| 39 | Blood pressure orthostatic decreased | FAERS: 1 | US FAERS | |
| 40 | Blunted affect | FAERS: 1 | US FAERS | |
| 41 | Burning sensation | FAERS: 1 | US FAERS | |
| 42 | Cardiac Arrest | FAERS: 1 | US FAERS | |
| 43 | Catatonia | FAERS: 1 | US FAERS | |
| 44 | Chorea | FAERS: 1 | US FAERS | |
| 45 | Confabulation | FAERS: 1 | US FAERS | |
| 46 | Cyanosis | FAERS: 1 | US FAERS | |
| 47 | Dehydration | FAERS: 1 | US FAERS | |
| 48 | Depressed Level of Consciousness | FAERS: 1 | US FAERS | |
| 49 | Depressed mood | FAERS: 1 | US FAERS | |
| 50 | Drug dispensing error | FAERS: 1 | US FAERS | |
| 51 | Drug effect incomplete | FAERS: 1 | US FAERS | |
| 52 | Dysphemia | FAERS: 1 | US FAERS | |
| 53 | Dysuria | FAERS: 1 | US FAERS | |
| 54 | Erythema | FAERS: 1 | US FAERS | |
| 55 | Facial Pain | FAERS: 1 | US FAERS | |
| 56 | Flushing | FAERS: 1 | US FAERS | |
| 57 | Formication | FAERS: 1 | US FAERS | |
| 58 | Gambling | FAERS: 1 | US FAERS | |
| 59 | Hallucinations, mixed | FAERS: 1 | US FAERS | |
| 60 | Hemiparesis | FAERS: 1 | US FAERS | |
| 61 | Hypersensitivity | FAERS: 1 | US FAERS | |
| 62 | Hypersomnia | FAERS: 1 | US FAERS | |
| 63 | Hypoxia | FAERS: 1 | US FAERS | |
| 64 | Illogical thinking | FAERS: 1 | US FAERS | |
| 65 | Joint swelling | FAERS: 1 | US FAERS | |
| 66 | Keratitis | FAERS: 1 | US FAERS | |
| 67 | Laceration | FAERS: 1 | US FAERS | |
| 68 | Lipoprotein (a) increased | FAERS: 1 | US FAERS | |
| 69 | Lobar Pneumonia | FAERS: 1 | US FAERS | |
| 70 | Malaise | FAERS: 1 | US FAERS | |
| 71 | Musculoskeletal stiffness | FAERS: 1 | US FAERS | |
| 72 | Myocardial Infarction | FAERS: 1 | US FAERS | |
| 73 | Nervousness | FAERS: 1 | US FAERS | |
| 74 | Neuroleptic Malignant Syndrome | FAERS: 1 | US FAERS | |
| 75 | Pallor | FAERS: 1 | US FAERS | |
| 76 | Paranoia | FAERS: 1 | US FAERS | |
| 77 | Petechiae | FAERS: 1 | US FAERS | |
| 78 | Physical product label issue | FAERS: 1 | US FAERS | |
| 79 | Product quality issue | FAERS: 1 | US FAERS | |
| 80 | Product use in unapproved indication | FAERS: 1 | US FAERS | |
| 81 | Rash erythematous | FAERS: 1 | US FAERS | |
| 82 | Respiratory Failure | FAERS: 1 | US FAERS | |
| 83 | Restlessness | FAERS: 1 | US FAERS | |
| 84 | Rheumatoid Arthritis | FAERS: 1 | US FAERS | |
| 85 | Septic Shock | FAERS: 1 | US FAERS | |
| 86 | Sinus Tachycardia | FAERS: 1 | US FAERS | |
| 87 | Somnolence | FAERS: 1 | US FAERS | |
| 88 | Suicide attempt | FAERS: 1 | US FAERS | |
| 89 | Therapeutic response unexpected | FAERS: 1 | US FAERS | |
| 90 | Therapeutic response unexpected with drug substitution | FAERS: 1 | US FAERS | |
| 91 | Tremor | FAERS: 1 | US FAERS | |
| 92 | Unevaluable event | FAERS: 1 | US FAERS | |
| 93 | Urticaria | FAERS: 1 | US FAERS | |
| 94 | Venous valve ruptured | FAERS: 1 | US FAERS | |
| 95 | Ataxia | Canada Vigilance: 1 | Canada Vigilance | |
| 96 | Atrial Fibrillation | Canada Vigilance: 1 | Canada Vigilance | |
| 97 | Muscle Spasticity | Canada Vigilance: 1 | Canada Vigilance | |
| 98 | Urinary Incontinence | Canada Vigilance: 1 | Canada Vigilance |
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