nalmefene
(WJBLNOPPDWQMCH-MBPVOVBZSA-N)
Structure
- SMILES
- C=C1CC[C@@]2([C@@]34[C@H]1Oc1c4c(C[C@H]2N(CC3)CC2CC2)ccc1O)O
- Type(s)
- Approved; Investigational; Withdrawn
- ATC code(s)
- N07BB05
- Molecular Formula:
- C21H25NO3
- Molecular Weight:
- 339.428
- Log P:
- 2.4504
- Hydrogen Bond Acceptor:
- 4
- Hydrogen Bond Donor:
- 2
- TPSA:
- 52.93
- CAS Number(s):
- 55096-26-9
Synonym(s)
1.
nalmefene
2.
6-desoxy-6-methylenenaltrexone
3.
Revex
4.
Selincro
5.
nalmefene hydrochloride
External Link(s)
Adverse Drug Event(s)
| Name | Number of Reports | Reference(s) | Data Source | |
|---|---|---|---|---|
| 1 | Abdominal Cramps | SIDER | ||
| 2 | Abdominal Pain | SIDER | ||
| 3 | Agitation | SIDER | ||
| 4 | Alcohol withdrawal syndrome | SIDER | ||
| 5 | Arthralgia | SIDER | ||
| 6 | Aspartate Aminotransferase Increased | SIDER | ||
| 7 | Asthenia | SIDER | ||
| 8 | Bradycardia | SIDER | ||
| 9 | Chills | SIDER | ||
| 10 | Discomfort | SIDER | ||
| 11 | Dissociation | SIDER | ||
| 12 | Disturbance in sexual arousal | SIDER | ||
| 13 | Dizziness | 3943269 17451401 | CTD SIDER | |
| 14 | Fatigue | 17451401 | CTD SIDER | |
| 15 | Feeling abnormal | SIDER | ||
| 16 | Headache | SIDER | ||
| 17 | Hepatitis | SIDER | ||
| 18 | Hypotension | SIDER | ||
| 19 | Malaise | SIDER | ||
| 20 | Malnutrition | SIDER | ||
| 21 | Musculoskeletal discomfort | SIDER | ||
| 22 | Myalgia | SIDER | ||
| 23 | Myoclonus | SIDER | ||
| 24 | Nausea | 17451401 | CTD SIDER | |
| 25 | Nervousness | SIDER | ||
| 26 | Palpitations | SIDER | ||
| 27 | Panic Disorder | 3680614 | CTD | |
| 28 | Pharyngitis | SIDER | ||
| 29 | Pruritus | SIDER | ||
| 30 | Sleep Initiation and Maintenance Disorders | 17451401 | CTD | |
| 31 | Somnolence | SIDER | ||
| 32 | Tachycardia | SIDER | ||
| 33 | Tension | SIDER | ||
| 34 | Traumatic liver injury | SIDER | ||
| 35 | Tremor | SIDER | ||
| 36 | Urinary Retention | SIDER | ||
| 37 | Vomiting | SIDER | ||
| 38 | Weight decreased | SIDER | ||
| 39 | nervous system disorder | SIDER |
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