Simendan
(WHXMKTBCFHIYNQ-SECBINFHSA-N)
Structure
- SMILES
- N#CC(=NNc1ccc(cc1)C1=NNC(=O)C[C@H]1C)C#N
- Type(s)
- Approved; Investigational
- ATC code(s)
- C01CX08
- Molecular Formula:
- C14H12N6O
- Molecular Weight:
- 280.285
- Log P:
- 1.1992
- Hydrogen Bond Acceptor:
- 7
- Hydrogen Bond Donor:
- 2
- TPSA:
- 113.43
- CAS Number(s):
- 141505-33-1
Synonym(s)
1.
Simendan
2.
((4-(1,4,5,6-tetrahydro-4-methyl-6-oxo-3-pyridazinyl)phenyl)hydrazono)propanedinitrile
3.
Dextrosimendan
4.
Levosimendan
5.
OR 1259
6.
OR-1259
7.
OR-1855
8.
Simadax
9.
OR 1855
External Link(s)
| MeSH | D000077464 |
| PubChem Compound | 3033825 |
| ChEBI | 50567 |
| CHEMBL | CHEMBL2051955 |
| DrugBank | DB00922 |
| DrugCentral | 1576 |
| KEGG | dr:D04720 |
| Therapeutic Target Database | D0C4HG |
| ZINC | 3915645 |
Adverse Drug Event(s)
| Name | Number of Reports | Reference(s) | Data Source | |
|---|---|---|---|---|
| 1 | Hypotension | FAERS: 2 | SIDER US FAERS | |
| 2 | Overdose | FAERS: 2 | US FAERS | |
| 3 | Expired product administered | FAERS: 1 | US FAERS | |
| 4 | Atrial Fibrillation | SIDER | ||
| 5 | Constipation | SIDER | ||
| 6 | Dizziness | SIDER | ||
| 7 | Headache | SIDER | ||
| 8 | Malnutrition | SIDER | ||
| 9 | Nausea | SIDER | ||
| 10 | Tachycardia | SIDER | ||
| 11 | Ventricular Fibrillation | SIDER | ||
| 12 | Vomiting | SIDER | ||
| 13 | nervous system disorder | SIDER |
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