MetaADEDB: Drug

MetaADEDB 2.0 @ LMMD

Picrotoxin

(VJKUPQSHOVKBCO-ZTYBEOBUSA-N)

Structure

SMILES: CC(=C)[C@@H]1C2OC(=O)C1[C@]1([C@]3([C@@H]2OC(=O)[C@]23C(C1)O2)C)O.O=C1OC2[C@H](C1[C@]1(O)C[C@@H]3[C@]4([C@@]1([C@@H]2OC4=O)C)O3)C(O)(C)C
Type(s): Experimental
Molecular Formula:: C30H34O13
Molecular Weight:: 602.583
Log P:: -0.9292
Hydrogen Bond Acceptor:: 13
Hydrogen Bond Donor:: 3
TPSA:: 190.95
CAS Number(s):: 124-87-8

Synonym(s)

Picrotoxin

External Link(s)

MeSH	D010852
PubChem Compound	31304
CHEMBL	CHEMBL1908342
DrugBank	DB00466
IUPHAR/BPS Guide to PHARMACOLOGY	4051
Therapeutic Target Database	D0KR9U

Adverse Drug Event(s)

	Name	Reference(s)	Data Source
1	Anxiety Disorders	12949675	CTD
2	Bradycardia	2894433	CTD
3	Catalepsy	View details 569589 3004539 6543001 8588288	CTD
4	Chorea	12459828 16967869 17922247	CTD
5	Cocaine-Related Disorders	17943439	CTD
6	Dyskinesia, Drug-Induced	7443083	CTD
7	Epilepsies, Partial	8332623	CTD
8	Epilepsy	View details 1922924 3822246 8437894 8868293	CTD
9	Glucose Metabolism Disorders	25456265	CTD
10	Hyperalgesia	9239313 11262592	CTD
11	Hypotension	8816361 10524271	CTD
12	Memory Disorders	12873623 15521558	CTD
13	Muscle Rigidity	3023105	CTD
14	Myoclonus	View details 2147669 2347607 2620967 7078834 12459828 16967869 17922247	CTD
15	Nerve Degeneration	19840816	CTD
16	Penile Diseases	7862903	CTD
17	Seizures	View details 200966 232053 565846 779804 840320 1193207 1280523 1329401 1334454 1409814 1413630 1490096 1513203 1639237 1654571 1675896 1711699 1794355 1897004 1921427 1970362 1977176 2087256 2308142 2341972 2406529 2440413 2451320 2507307 2558775 2734334 2755280 2827698 2854931 2859023 2872692 2872934 2931304 2995953 3000472 3004930 3010161 3109689 3196380 3198244 3218632 3575358 6090968 6102883 6133822 6306485 6316193 6433367 6442955 6542488 6549050 6653673 6686073 6807671 6834037 7073000 7189834 7291236 7305545 7574061 7617694 7671436 7698200 7875556 7913897 7967231 7976808 8011125 8063357 8103921 8232867 8274150 8326083 8332623 8384519 8413055 8469708 8575085 8598176 8635557 8645877 8930322 8939481 8954991 9121635 9140226 9169290 9300267 9314026 9500968 9665662 10193651 10211593 10213161 10357070 10378304 10411992 10605059 10776465 10825578 11146048 11177229 11206082 11685388 11699190 11755695 12062587 12175447 12184502 12350394 12413711 12429195 12667892 12829730 12873623 12948618 12956907 12957225 12967596 14066625 14190466 14637124 14724035 15266951 15521558 15527415 15582831 15665939 15698621 15740777 16176064 16313900 16368191 16573711 16629370 16679555 16775810 16872668 16920333 17074045 17439812 17583456 17728537 17877149 17976969 18021373 18346762 18379620 18435754 18657594 19429380 19553180 19723069 19783516 19840816 19893603 19951740 20002750 20162077 20362043 20940032 21454176 25490531 29038840 29596924	CTD
18	Status Epilepticus	9255601	CTD
19	Stereotypic Movement Disorder	6543001	CTD
20	Tremor	181685 6090968 30590068	CTD

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