MetaADEDB 2.0 @ LMMD
oritavancin
(VHFGEBVPHAGQPI-LXKZPTCJSA-N)
Structure
SMILES
OC[C@H]1O[C@@H](Oc2c3Oc4ccc(cc4Cl)[C@@H](O)[C@@H](NC(=O)[C@@H](CC(C)C)NC)C(=O)N[C@H](C(=O)N[C@@H]4c(c3)cc2Oc2ccc(cc2Cl)[C@@H](O[C@@H]2O[C@@H](C)[C@@H]([C@@](C2)(C)N)O)[C@@H]2NC(=O)[C@H](NC4=O)c3ccc(c(c3)c3c(O)cc(cc3[C@H](NC2=O)C(=O)O)O)O)CC(=O)N)[C@@H]([C@H]([C@@H]1O)O)O[C@@H]1O[C@@H](C)[C@@H]([C@@](C1)(C)NCc1ccc(cc1)c1ccc(cc1)Cl)O
Type(s)
Approved; Investigational
ATC code(s)
J01XA05
Molecular Formula:
C86H97Cl3N10O26
Molecular Weight:
1793.100
Log P:
8.7125
Hydrogen Bond Acceptor:
36
Hydrogen Bond Donor:
20
TPSA:
560.98
CAS Number(s):
171099-57-3
Synonym(s)
1.
oritavancin
2.
LY 333328
3.
LY-333328
4.
LY333328
5.
Orbactiv
External Link(s)
MeSHC100708
PubChem Compound101991076
16136912
ChEBI82699
CHEMBLCHEMBL1688530
DrugBankDB04911
DrugCentral4678
KEGGcpd:C12034
Adverse Drug Event(s)
NameNumber of ReportsReference(s)Data Source
1ChillsFAERS: 5US FAERS
2TremorFAERS: 4US FAERS
3Back PainFAERS: 2US FAERS
4Chest PainFAERS: 2US FAERS
5ErythemaFAERS: 2US FAERS
6PruritusFAERS: 2US FAERS
7AbasiaFAERS: 1US FAERS
8AnxietyFAERS: 1US FAERS
9AstheniaFAERS: 1US FAERS
10Blood glucose fluctuationFAERS: 1US FAERS
11Feeling ColdFAERS: 1US FAERS
12HeadacheFAERS: 1US FAERS
13Livedo ReticularisFAERS: 1US FAERS
14Mechanical urticariaFAERS: 1US FAERS
15NauseaFAERS: 1US FAERS
16PainFAERS: 1US FAERS
17PalpitationsFAERS: 1US FAERS
18Respiratory DepressionFAERS: 1US FAERS
19TachycardiaFAERS: 1US FAERS
20Therapy cessationFAERS: 1US FAERS
21Therapy non-responderFAERS: 1US FAERS
22ThrombocytopeniaFAERS: 1US FAERS
23UrticariaFAERS: 1US FAERS
24VomitingFAERS: 1US FAERS
25WheezingFAERS: 1US FAERS
26Staphylococcal Infections19188393CTD
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