carboprost tromethamine
(UMMADZJLZAPZAW-XOWPVRJPSA-N)
Structure
- SMILES
- OCC(CO)(CO)N.CCCCC[C@@](/C=C/[C@H]1[C@H](O)C[C@@H]([C@@H]1C/C=C\CCCC(=O)O)O)(O)C
- Molecular Formula:
- C25H47NO8
- Molecular Weight:
- 489.643
- Log P:
- 1.7941
- Hydrogen Bond Acceptor:
- 9
- Hydrogen Bond Donor:
- 8
- TPSA:
- 184.7
- CAS Number(s):
- 58551-69-2
Synonym(s)
1.
carboprost tromethamine
2.
15-methylprostaglandin F2alpha-tromethamine
3.
Hemabate
4.
Prostin M-15
5.
carboprost trometamol
External Link(s)
| MeSH | C062843 |
| PubChem Compound | 5281074 |
| CHEMBL | CHEMBL1237105 |
| KEGG | dr:D00682 |
Adverse Drug Event(s)
| Name | Number of Reports | Reference(s) | Data Source | |
|---|---|---|---|---|
| 1 | Incorrect route of drug administration | FAERS: 6 | US FAERS | |
| 2 | Bronchospasm | FAERS: 5 | US FAERS | |
| 3 | Cardiac Arrest | FAERS: 4 | US FAERS | |
| 4 | Vomiting | FAERS: 4 | US FAERS | |
| 5 | Headache | FAERS: 3 Canada Vigilance: 1 | Canada Vigilance US FAERS | |
| 6 | Injection site bruising | FAERS: 3 | US FAERS | |
| 7 | Nausea | FAERS: 3 Canada Vigilance: 1 | Canada Vigilance US FAERS | |
| 8 | Product use issue | FAERS: 3 | US FAERS | |
| 9 | Anaphylactic shock | FAERS: 2 | US FAERS | |
| 10 | Chest discomfort | FAERS: 2 | US FAERS | |
| 11 | Dizziness | FAERS: 2 Canada Vigilance: 2 | Canada Vigilance US FAERS | |
| 12 | Injection site urticaria | FAERS: 2 | US FAERS | |
| 13 | Palpitations | FAERS: 2 | US FAERS | |
| 14 | Poor quality drug administered | FAERS: 2 | US FAERS | |
| 15 | Product quality issue | FAERS: 2 | US FAERS | |
| 16 | Pulmonary Hypertension | FAERS: 2 | US FAERS | |
| 17 | Respiratory arrest | FAERS: 2 | US FAERS | |
| 18 | Abdominal Pain | FAERS: 1 | US FAERS | |
| 19 | Abdominal discomfort | FAERS: 1 | US FAERS | |
| 20 | Amnesia | FAERS: 1 | US FAERS | |
| 21 | Asthma | FAERS: 1 | US FAERS | |
| 22 | Chills | FAERS: 1 | US FAERS | |
| 23 | Cold sweat | FAERS: 1 | US FAERS | |
| 24 | Cyanosis | FAERS: 1 | US FAERS | |
| 25 | Drug administration error | FAERS: 1 | US FAERS | |
| 26 | Drug ineffective | FAERS: 1 | US FAERS | |
| 27 | Ejection Fraction Decreased | FAERS: 1 | US FAERS | |
| 28 | Enterococcal infection | FAERS: 1 | US FAERS | |
| 29 | Flushing | FAERS: 1 | US FAERS | |
| 30 | Glaucoma | FAERS: 1 Canada Vigilance: 2 | Canada Vigilance US FAERS | |
| 31 | Hyperpyrexia | FAERS: 1 | US FAERS | |
| 32 | Hypersensitivity | FAERS: 1 | US FAERS | |
| 33 | Hypotension | FAERS: 1 | US FAERS | |
| 34 | Injection Site Reaction | FAERS: 1 | US FAERS | |
| 35 | Lividity | FAERS: 1 | US FAERS | |
| 36 | Local reaction | FAERS: 1 | US FAERS | |
| 37 | Monoplegia | FAERS: 1 | US FAERS | |
| 38 | PO2 decreased | FAERS: 1 | US FAERS | |
| 39 | Peripartum cardiomyopathy | FAERS: 1 | US FAERS | |
| 40 | Pruritus | FAERS: 1 | US FAERS | |
| 41 | Respiratory distress | FAERS: 1 | US FAERS | |
| 42 | Rhonchi | FAERS: 1 | US FAERS | |
| 43 | Skin reaction | FAERS: 1 | US FAERS | |
| 44 | Stridor | FAERS: 1 | US FAERS | |
| 45 | Tachycardia | FAERS: 1 | US FAERS | |
| 46 | Tremor | FAERS: 1 | US FAERS | |
| 47 | Vertigo | FAERS: 1 Canada Vigilance: 1 | Canada Vigilance US FAERS | |
| 48 | Wheezing | FAERS: 1 | US FAERS | |
| 49 | Cystitis | 1404668 | CTD | |
| 50 | Hematuria | 2369708 8455230 | CTD | |
| 51 | Hemorrhage | 1404668 | CTD | |
| 52 | Impaired driving ability | Canada Vigilance: 1 | Canada Vigilance | |
| 53 | Urinary Bladder Diseases | 12956853 | CTD | |
| 54 | Uterine Rupture | 12956853 | CTD |
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