MetaADEDB 2.0 @ LMMD
tirilazad
(RBKASMJPSJDQKY-RBFSKHHSSA-N)
Structure
SMILES
O=C1C=C[C@]2(C(=C1)CC[C@@H]1C2=CC[C@]2([C@H]1C[C@H]([C@@H]2C(=O)CN1CCN(CC1)c1cc(nc(n1)N1CCCC1)N1CCCC1)C)C)C
Type(s)
Investigational
ATC code(s)
N07XX01
Molecular Formula:
C38H52N6O2
Molecular Weight:
624.858
Log P:
5.5912
Hydrogen Bond Acceptor:
8
Hydrogen Bond Donor:
0
TPSA:
72.88
CAS Number(s):
110101-66-1
Synonym(s)
1.
tirilazad
2.
21-(4-(2,6-di-1-pyrrolidinyl-4-pyrimidinyl)-1-piperazinyl)-16-methylpregna-1,4,9(11)-triene-3,20-dione monomethane sulfonate
3.
Freedox
4.
U 74006F
5.
U-74006
6.
U-74006F
7.
U74006F
8.
pregna-1,4,9(11)-triene-3,20-dione, 21-(4-(2,6-di-1-pyrrolidinyl-4-pyrimidinyl)-1-piperazinyl)-16-methyl-, (16alpha)-, monomethanesulfonate
9.
tirilazad mesylate
10.
tirilazad mesylate hydrate
External Link(s)
MeSHC053355
PubChem Compound104903
ChEBI135853
CHEMBLCHEMBL1630578
DrugBankDB13050
DrugCentral4063
KEGGdr:D08606
ZINC43133316
Adverse Drug Event(s)
NameNumber of ReportsReference(s)Data Source
1Acute kidney injury8891671CTD
2Ischemia8891671CTD
3Reperfusion Injury8891671CTD
4Subarachnoid Hemorrhage9533108CTD
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