MetaADEDB 2.0 @ LMMD
azilsartan medoxomil
(QJFSABGVXDWMIW-UHFFFAOYSA-N)
Structure
SMILES
CCOc1nc2c(n1Cc1ccc(cc1)c1ccccc1c1noc(=O)[nH]1)c(ccc2)C(=O)OCc1oc(=O)oc1C
Type(s)
Approved; Investigational
ATC code(s)
C09CA09; C09DA09
Molecular Formula:
C30H24N4O8
Molecular Weight:
568.534
Log P:
4.7052
Hydrogen Bond Acceptor:
11
Hydrogen Bond Donor:
1
TPSA:
155.59
CAS Number(s):
863031-21-4
Synonym(s)
1.
azilsartan medoxomil
2.
TAK 491
3.
TAK-491
4.
TAK491
External Link(s)
MeSHC557413
PubChem Compound135409642
11238823
ChEBI68845
CHEMBLCHEMBL2028661
DrugBankDB08822
DrugCentral4322
IUPHAR/BPS Guide to PHARMACOLOGY6900
KEGGdr:D08067
dr:D08865
Therapeutic Target DatabaseD0A2RA
ZINC14210642
Adverse Drug Event(s)
NameNumber of ReportsReference(s)Data Source
1DizzinessFAERS: 27US FAERS
2HeadacheFAERS: 26
Canada Vigilance: 2
Canada Vigilance
US FAERS
3Drug ineffectiveFAERS: 21
Canada Vigilance: 4
Canada Vigilance
US FAERS
4Incorrect product storageFAERS: 16US FAERS
5Poor quality drug administeredFAERS: 16US FAERS
6Wrong technique in product usage processFAERS: 16US FAERS
7HypotensionFAERS: 15US FAERS
8MalaiseFAERS: 15US FAERS
9Product quality issueFAERS: 15US FAERS
10NauseaFAERS: 14US FAERS
11Feeling abnormalFAERS: 11US FAERS
12FatigueFAERS: 9US FAERS
13AngioedemaFAERS: 8
Canada Vigilance: 1
Canada Vigilance
US FAERS
14Product closure removal difficultFAERS: 8US FAERS
15AstheniaFAERS: 7US FAERS
16Product contaminationFAERS: 6US FAERS
17Product storage errorFAERS: 6US FAERS
18VomitingFAERS: 6US FAERS
19Abdominal discomfortFAERS: 5US FAERS
20Peripheral swellingFAERS: 5US FAERS
21SyncopeFAERS: 5US FAERS
22Weight decreasedFAERS: 5US FAERS
23Cerebrovascular accidentFAERS: 4US FAERS
24Chest PainFAERS: 4US FAERS
25Product container issueFAERS: 4US FAERS
26Product dispensing errorFAERS: 4US FAERS
27Product taste abnormalFAERS: 4US FAERS
28AlopeciaFAERS: 3US FAERS
29Blood potassium increasedFAERS: 3US FAERS
30Chest discomfortFAERS: 3US FAERS
31Drug dispensing errorFAERS: 3US FAERS
32DysphoniaFAERS: 3US FAERS
33Expired product administeredFAERS: 3US FAERS
34LethargyFAERS: 3US FAERS
35MyalgiaFAERS: 3US FAERS
36PalpitationsFAERS: 3US FAERS
37Product physical issueFAERS: 3US FAERS
38ArthralgiaFAERS: 2US FAERS
39Atrial FibrillationFAERS: 2US FAERS
40Blood creatinine increasedFAERS: 2US FAERS
41Blood pressure fluctuationFAERS: 2US FAERS
42Blood triglycerides increasedFAERS: 2US FAERS
43Bone painFAERS: 2US FAERS
44Drug dose omissionFAERS: 2US FAERS
45GoutFAERS: 2US FAERS
46Hypertensive crisisFAERS: 2US FAERS
47Inappropriate schedule of drug administrationFAERS: 2US FAERS
48Lip swellingFAERS: 2US FAERS
49Prescribed underdoseFAERS: 2US FAERS
50Product packaging issueFAERS: 2US FAERS
51Pulmonary EmbolismFAERS: 2US FAERS
52Unevaluable eventFAERS: 2US FAERS
53Withdrawal hypertensionFAERS: 2US FAERS
54Abdominal PainFAERS: 1US FAERS
55Accidental exposure to product packagingFAERS: 1US FAERS
56Adverse eventFAERS: 1US FAERS
57Alanine Aminotransferase IncreasedFAERS: 1US FAERS
58ArteriosclerosisFAERS: 1US FAERS
59Aspartate Aminotransferase IncreasedFAERS: 1US FAERS
60Back PainFAERS: 1US FAERS
61BlindnessFAERS: 1US FAERS
62Blood cholesterol increasedFAERS: 1US FAERS
63Blood potassium decreasedFAERS: 1US FAERS
64Blood pressure inadequately controlledFAERS: 1
Canada Vigilance: 1
Canada Vigilance
US FAERS
65Blood sodium decreasedFAERS: 1US FAERS
66Burning sensationFAERS: 1US FAERS
67Cardiac ArrestFAERS: 1US FAERS
68ChromaturiaFAERS: 1US FAERS
69ConstipationFAERS: 1US FAERS
70CyanosisFAERS: 1US FAERS
71DehydrationFAERS: 1US FAERS
72DependenceFAERS: 1US FAERS
73Diabetic FootFAERS: 1US FAERS
74DiscomfortFAERS: 1US FAERS
75Drug effect delayedFAERS: 1US FAERS
76DystoniaFAERS: 1US FAERS
77DysuriaFAERS: 1US FAERS
78Emotional disorderFAERS: 1US FAERS
79Erection increasedFAERS: 1US FAERS
80Febrile infectionFAERS: 1US FAERS
81Feeling jitteryFAERS: 1US FAERS
82Impaired work abilityFAERS: 1US FAERS
83Inability to afford medicationFAERS: 1US FAERS
84IncoherentFAERS: 1US FAERS
85Incorrect dose administeredFAERS: 1US FAERS
86Limb discomfortFAERS: 1US FAERS
87Memory impairmentFAERS: 1US FAERS
88Mouth swellingFAERS: 1US FAERS
89Muscle tightnessFAERS: 1US FAERS
90Myocardial InfarctionFAERS: 1US FAERS
91NasopharyngitisFAERS: 1US FAERS
92Neck PainFAERS: 1US FAERS
93NephrolithiasisFAERS: 1US FAERS
94NervousnessFAERS: 1US FAERS
95NocturiaFAERS: 1US FAERS
96Oral painFAERS: 1US FAERS
97Oropharyngeal painFAERS: 1US FAERS
98Pancreatic carcinomaFAERS: 1US FAERS
99Peripheral arterial occlusive diseaseFAERS: 1US FAERS
100Pharyngeal swellingFAERS: 1US FAERS
101PneumoniaFAERS: 1US FAERS
102PresyncopeFAERS: 1US FAERS
103Product distribution issueFAERS: 1US FAERS
104Product dose omissionFAERS: 1US FAERS
105Product packaging quantity issueFAERS: 1US FAERS
106Product prescribing errorFAERS: 1US FAERS
107Product size issueFAERS: 1US FAERS
108Product substitution issueFAERS: 1US FAERS
109Product use complaintFAERS: 1US FAERS
110PruritusFAERS: 1US FAERS
111PurpuraFAERS: 1US FAERS
112Rash erythematousFAERS: 1US FAERS
113Rebound effectFAERS: 1US FAERS
114Respiratory FailureFAERS: 1US FAERS
115Respiratory tract congestionFAERS: 1US FAERS
116Restless Legs SyndromeFAERS: 1US FAERS
117RhabdomyolysisFAERS: 1US FAERS
118SluggishnessFAERS: 1US FAERS
119SomnolenceFAERS: 1US FAERS
120TachycardiaFAERS: 1US FAERS
121Therapeutic response unexpectedFAERS: 1US FAERS
122Urinary tract infectionFAERS: 1US FAERS
123UrticariaFAERS: 1US FAERS
124VertigoFAERS: 1US FAERS
125Visual ImpairmentFAERS: 1US FAERS
126WheezingFAERS: 1US FAERS
127Wrong technique in drug usage processFAERS: 1US FAERS
128HypersensitivityCanada Vigilance: 1Canada Vigilance
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