MetaADEDB 2.0 @ LMMD
MK-886
(QAOAOVKBIIKRNL-UHFFFAOYSA-N)
Structure
SMILES
Clc1ccc(cc1)Cn1c2ccc(cc2c(c1CC(C(=O)O)(C)C)SC(C)(C)C)C(C)C
Molecular Formula:
C27H34ClNO2S
Molecular Weight:
472.082
Log P:
8.0103
Hydrogen Bond Acceptor:
4
Hydrogen Bond Donor:
1
TPSA:
67.53
CAS Number(s):
118414-82-7
Synonym(s)
1.
MK-886
2.
1-((4-chlorophenyl)methyl)-3-((1,1-dimethylethyl)thio)-alpha, alpha-dimethyl-5-(1-methylethyl)-1h-indole-2-propanoic acid
3.
1H-indole-2-propanoic acid, 1-((4-chlorophenyl)methyl)-3-((1,1-dimethylethyl)thio)-alpha, alpha-dimethyl-5-(1-methylethyl)-
4.
3-(1-(4-chlorobenzyl)-3-t-butylthio-5-isopropylindol-2-yl)-2,2-dimethylpropanoic acid
5.
L 663536
6.
L-663,536
7.
MK 886
8.
MK886 cpd
External Link(s)
MeSHC060893
PubChem Compound3651377
BindingDB50006805
ChEBI75390
CHEMBLCHEMBL29097
IUPHAR/BPS Guide to PHARMACOLOGY2655
Therapeutic Target DatabaseD0K2ER
ZINC1536875
Adverse Drug Event(s)
NameNumber of ReportsReference(s)Data Source
1Atherosclerosis22059882CTD
2Edema7990266CTD
3Hypotension19896470CTD
4Lung Neoplasms15899809CTD
5Pruritus17827870CTD
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