MetaADEDB 2.0 @ LMMD
Clemastine
(PMGQWSIVQFOFOQ-YKVZVUFRSA-N)
Structure
SMILES
Clc1ccc(cc1)[C@@](c1ccccc1)(OCC[C@H]1CCCN1C)C.OC(=O)/C=C/C(=O)O
Molecular Formula:
C25H30ClNO5
Molecular Weight:
459.962
Log P:
4.7541
Hydrogen Bond Acceptor:
6
Hydrogen Bond Donor:
2
TPSA:
87.07
CAS Number(s):
14976-57-9
Synonym(s)
1.
Clemastine
2.
Meclastine
3.
Mecloprodin
4.
2-(2-(1-(4-Chlorophenyl)-1-phenylethoxy)ethyl)-1-methylpyrrolidine
5.
Clemastine Fumarate
6.
HS-592
7.
Tavegyl
8.
Tavist
9.
HS 592
10.
HS592
External Link(s)
MeSHD002974
PubChem Compound5281069
6426695
ChEBI3739
CHEMBLCHEMBL1200795
Therapeutic Target DatabaseD06QQS
Adverse Drug Event(s)
NameNumber of ReportsReference(s)Data Source
1UrticariaFAERS: 7
Canada Vigilance: 1		Canada Vigilance
US FAERS
2HeadacheFAERS: 6
Canada Vigilance: 1		Canada Vigilance
US FAERS
3PruritusFAERS: 5US FAERS
4SomnolenceFAERS: 4
Canada Vigilance: 1		Canada Vigilance
US FAERS
5Alanine Aminotransferase IncreasedFAERS: 3US FAERS
6Aspartate Aminotransferase IncreasedFAERS: 3US FAERS
7Blood lactate dehydrogenase increasedFAERS: 3US FAERS
8BradycardiaFAERS: 3US FAERS
9ChillsFAERS: 3US FAERS
10DizzinessFAERS: 3
Canada Vigilance: 2		Canada Vigilance
US FAERS
11Drug ineffectiveFAERS: 3US FAERS
12ErythemaFAERS: 3US FAERS
13Gamma-Glutamyltransferase IncreasedFAERS: 3US FAERS
14HypersensitivityFAERS: 3US FAERS
15HypotensionFAERS: 3US FAERS
16NauseaFAERS: 3US FAERS
17Abdominal discomfortFAERS: 2US FAERS
18Anaphylactic shockFAERS: 2US FAERS
19Blood alkaline phosphatase increasedFAERS: 2US FAERS
20CryingFAERS: 2US FAERS
21EpilepsyFAERS: 2US FAERS
22Inappropriate schedule of drug administrationFAERS: 2US FAERS
23MalaiseFAERS: 2US FAERS
24OverdoseFAERS: 2US FAERS
25PiloerectionFAERS: 2US FAERS
26RhinitisFAERS: 2US FAERS
27SneezingFAERS: 2US FAERS
28Throat irritationFAERS: 2US FAERS
29VomitingFAERS: 2
Canada Vigilance: 1		Canada Vigilance
US FAERS
30Wrong technique in product usage processFAERS: 2US FAERS
31Abdominal PainFAERS: 1US FAERS
32Arthropod biteFAERS: 1US FAERS
33AsthmaFAERS: 1US FAERS
34BronchospasmFAERS: 1US FAERS
35CatarrhFAERS: 1US FAERS
36ChokingFAERS: 1US FAERS
37Cold sweatFAERS: 1US FAERS
38ConjunctivitisFAERS: 1US FAERS
39Disease ProgressionFAERS: 1US FAERS
40Drug DependenceFAERS: 1US FAERS
41Drug ineffective for unapproved indicationFAERS: 1US FAERS
42EczemaFAERS: 1US FAERS
43Expired drug administeredFAERS: 1US FAERS
44Eye irritationFAERS: 1US FAERS
45FatigueFAERS: 1US FAERS
46Feeling abnormalFAERS: 1US FAERS
47Feeling of body temperature changeFAERS: 1US FAERS
48GlaucomaFAERS: 1US FAERS
49HypersomniaFAERS: 1US FAERS
50HyperventilationFAERS: 1US FAERS
51Incorrect dose administeredFAERS: 1US FAERS
52MalnutritionFAERS: 1US FAERS
53Mental impairmentFAERS: 1US FAERS
54Nasal discomfortFAERS: 1US FAERS
55Nerve injuryFAERS: 1US FAERS
56No adverse eventFAERS: 1US FAERS
57Panic DisorderFAERS: 1US FAERS
58ParanoiaFAERS: 1US FAERS
59PneumoniaFAERS: 1US FAERS
60PresyncopeFAERS: 1US FAERS
61Product use issueFAERS: 1US FAERS
62Reaction to drug excipientsFAERS: 1US FAERS
63SinusitisFAERS: 1US FAERS
64SwellingFAERS: 1US FAERS
65SyncopeFAERS: 1
Canada Vigilance: 1		Canada Vigilance
US FAERS
66TachycardiaFAERS: 1US FAERS
67Therapeutic response changedFAERS: 1US FAERS
68Therapeutic response unexpectedFAERS: 1US FAERS
69Tongue blisteringFAERS: 1US FAERS
70TremorFAERS: 1US FAERS
71Urinary RetentionFAERS: 1US FAERS
72Wound ComplicationFAERS: 1US FAERS
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