gadolinium ethoxybenzyl DTPA
(PCZHWPSNPWAQNF-LMOVPXPDSA-K)
Structure
- SMILES
- CCOc1ccc(cc1)C[C@H](N(CC(=O)[O-])CC(=O)[O-])CN(CC(=O)[O-])CCN(CC(=O)[O-])CC(=O)[O-].[Gd+3].[H+].[H+]
- Type(s)
- Approved
- ATC code(s)
- V08CA10
- Molecular Formula:
- C23H28GdN3O11
- Molecular Weight:
- 681.748
- Log P:
- -7.3481
- Hydrogen Bond Acceptor:
- 14
- Hydrogen Bond Donor:
- 0
- TPSA:
- 219.6
- CAS Number(s):
- 135326-11-3
Synonym(s)
1.
gadolinium ethoxybenzyl DTPA
2.
Eovist
3.
Gd-EOB-DTPA
4.
Primovist
5.
disodium gadoxetate
6.
gadolinium (4S)-4-(4-ethoxybenzyl)-3,6,9-tris(carboxylatomethyl)-3,6,9-triazaundecanoic acid disodium salt
7.
gadolinium ethoxybenzyl diethylenetriaminepentaacetic acid
8.
gadoxetate disodium
9.
gadoxetic acid
10.
gadoxetic acid disodium
External Link(s)
Adverse Drug Event(s)
| Name | Number of Reports | Reference(s) | Data Source | |
|---|---|---|---|---|
| 1 | Nausea | FAERS: 13 | SIDER US FAERS | |
| 2 | Malaise | FAERS: 8 | SIDER US FAERS | |
| 3 | Urticaria | FAERS: 5 | SIDER US FAERS | |
| 4 | Vomiting | FAERS: 5 | SIDER US FAERS | |
| 5 | Chills | FAERS: 4 | SIDER US FAERS | |
| 6 | Dizziness | FAERS: 4 | SIDER US FAERS | |
| 7 | Hypotension | FAERS: 4 | SIDER US FAERS | |
| 8 | Unresponsive to stimuli | FAERS: 4 | US FAERS | |
| 9 | Adverse event | FAERS: 3 | US FAERS | |
| 10 | Chest discomfort | FAERS: 3 | US FAERS | |
| 11 | Cold sweat | FAERS: 3 | US FAERS | |
| 12 | Erythema | FAERS: 3 | US FAERS | |
| 13 | Respiratory arrest | FAERS: 3 | US FAERS | |
| 14 | Amnesia | FAERS: 2 | US FAERS | |
| 15 | Anaphylactoid Reaction | FAERS: 2 | SIDER US FAERS | |
| 16 | Anxiety | FAERS: 2 | US FAERS | |
| 17 | Burning sensation | FAERS: 2 | US FAERS | |
| 18 | Cyanosis | FAERS: 2 | US FAERS | |
| 19 | Disorientation | FAERS: 2 | US FAERS | |
| 20 | Electromechanical dissociation | FAERS: 2 | US FAERS | |
| 21 | Presyncope | FAERS: 2 | US FAERS | |
| 22 | Pruritus | FAERS: 2 | SIDER US FAERS | |
| 23 | Urinary Incontinence | FAERS: 2 | US FAERS | |
| 24 | Abdominal Pain | FAERS: 1 | SIDER US FAERS | |
| 25 | Angioedema | FAERS: 1 | US FAERS | |
| 26 | Aphasia | FAERS: 1 | US FAERS | |
| 27 | Arthralgia | FAERS: 1 | US FAERS | |
| 28 | Asthma | FAERS: 1 | US FAERS | |
| 29 | Blood creatinine increased | FAERS: 1 | US FAERS | |
| 30 | Bradycardia | FAERS: 1 | US FAERS | |
| 31 | Bronchospasm | FAERS: 1 | US FAERS | |
| 32 | Cardiac Arrest | FAERS: 1 | US FAERS | |
| 33 | Cardiovascular insufficiency | FAERS: 1 | US FAERS | |
| 34 | Chest Pain | FAERS: 1 | SIDER US FAERS | |
| 35 | Choking | FAERS: 1 | US FAERS | |
| 36 | Contrast media reaction | FAERS: 1 | US FAERS | |
| 37 | Dementia | FAERS: 1 | US FAERS | |
| 38 | Drug ineffective | FAERS: 1 | US FAERS | |
| 39 | Dyspepsia | FAERS: 1 | US FAERS | |
| 40 | Dysphonia | FAERS: 1 | US FAERS | |
| 41 | Eye pain | FAERS: 1 | US FAERS | |
| 42 | Feeling abnormal | FAERS: 1 | SIDER US FAERS | |
| 43 | Flushing | FAERS: 1 | SIDER US FAERS | |
| 44 | Foaming at mouth | FAERS: 1 | US FAERS | |
| 45 | Mental impairment | FAERS: 1 | US FAERS | |
| 46 | Musculoskeletal discomfort | FAERS: 1 | US FAERS | |
| 47 | Nephrotic Syndrome | FAERS: 1 | US FAERS | |
| 48 | Oropharyngeal discomfort | FAERS: 1 | US FAERS | |
| 49 | Petechiae | FAERS: 1 | US FAERS | |
| 50 | Respiratory distress | FAERS: 1 | SIDER US FAERS | |
| 51 | Restlessness | FAERS: 1 | US FAERS | |
| 52 | Retrograde amnesia | FAERS: 1 | US FAERS | |
| 53 | Rhonchi | FAERS: 1 | US FAERS | |
| 54 | Shock | FAERS: 1 | SIDER US FAERS | |
| 55 | Tachyarrhythmia | FAERS: 1 | US FAERS | |
| 56 | Tachycardia | FAERS: 1 | SIDER US FAERS | |
| 57 | Throat irritation | FAERS: 1 | US FAERS | |
| 58 | Traumatic fracture | FAERS: 1 | US FAERS | |
| 59 | Wheezing | FAERS: 1 | US FAERS | |
| 60 | Agitation | SIDER | ||
| 61 | Akathisia | SIDER | ||
| 62 | Anaphylactic shock | SIDER | ||
| 63 | Asthenia | SIDER | ||
| 64 | Back Pain | SIDER | ||
| 65 | Conjunctivitis | SIDER | ||
| 66 | Dermatitis | SIDER | ||
| 67 | Discomfort | SIDER | ||
| 68 | Dysgeusia | SIDER | ||
| 69 | Fatigue | SIDER | ||
| 70 | Gastrointestinal Pain | SIDER | ||
| 71 | Headache | SIDER | ||
| 72 | Hypersensitivity | SIDER | ||
| 73 | Injection Site Reaction | SIDER | ||
| 74 | Injection site burning | SIDER | ||
| 75 | Injection site coldness | SIDER | ||
| 76 | Injection site extravasation | SIDER | ||
| 77 | Injection site irritation | SIDER | ||
| 78 | Injection site pain | SIDER | ||
| 79 | Nephrogenic Systemic Fibrosis | SIDER | ||
| 80 | Pallor | SIDER | ||
| 81 | Palpitations | SIDER | ||
| 82 | Rhinitis | SIDER | ||
| 83 | Sneezing | SIDER | ||
| 84 | Tremor | SIDER | ||
| 85 | Vertigo | SIDER | ||
| 86 | nervous system disorder | SIDER |
Powered by :
Page last updated at 2020-05-25 10:01:57 (Asia/Shanghai) | You are visitor No. 120237
Copyright © 2019-2020 Laboratory of Molecular Modeling and Design, Shanghai Key Laboratory of New Drug Design, School of Pharmacy, East China University of Science and Technology. All rights reserved.