MetaADEDB 2.0 @ LMMD
Piribedil
(OQDPVLVUJFGPGQ-UHFFFAOYSA-N)
Structure
SMILES
c1cnc(nc1)N1CCN(CC1)Cc1ccc2c(c1)OCO2
Type(s)
Investigational
ATC code(s)
N04BC08
Molecular Formula:
C16H18N4O2
Molecular Weight:
298.340
Log P:
1.5304
Hydrogen Bond Acceptor:
6
Hydrogen Bond Donor:
0
TPSA:
50.72
CAS Number(s):
3605-01-4; 78213-63-5; 622744
Synonym(s)
1.
Piribedil
2.
Piribendyl
3.
ET-495
4.
EU-4200
5.
Piribedil Hydrochloride
6.
Piribedil Mesylate
7.
Piribedil Mono-hydrochloride
8.
Trivastal
9.
ET 495
10.
ET495
11.
EU 4200
12.
EU4200
13.
Hydrochloride, Piribedil
14.
Mesylate, Piribedil
15.
Mono-hydrochloride, Piribedil
16.
Piribedil Mono hydrochloride
External Link(s)
MeSHD010891
PubChem Compound4850
BindingDB85092
ChEBI92833
CHEMBLCHEMBL1371770
DrugBankDB12478
DrugCentral2202
IUPHAR/BPS Guide to PHARMACOLOGY49
KEGGdr:D07305
Therapeutic Target DatabaseD07GXY
ZINC19537374
Adverse Drug Event(s)
NameNumber of ReportsReference(s)Data Source
1AbasiaOFFSIDES
2AkinesiaOFFSIDES
3Alanine Aminotransferase IncreasedOFFSIDES
4Altered state of consciousnessOFFSIDES
5AmimiaOFFSIDES
6AmphetaminesOFFSIDES
7AthetosisOFFSIDES
8Atrial tachycardiaOFFSIDES
9Atrioventricular BlockOFFSIDES
10AuraOFFSIDES
11Blood alkaline phosphatase increasedOFFSIDES
12Blood cholesterolOFFSIDES
13Blood creatine phosphokinase increasedOFFSIDES
14Blood creatinine increasedOFFSIDES
15Blood sodiumOFFSIDES
16Blood thyroid stimulating hormone increasedOFFSIDES
17Blood urea increasedOFFSIDES
18Brain natriuretic peptide increasedOFFSIDES
19BronchopneumopathyOFFSIDES
20Bulbar palsyOFFSIDES
21Burning sensationOFFSIDES
22Cerebral atrophyOFFSIDES
23CheilitisOFFSIDES
24CholangiolitisOFFSIDES
25ColitisOFFSIDES
26ConfabulationOFFSIDES
27Confusion944394
1091122		CTD
28Conversion disorderOFFSIDES
29Creatinine renal clearance decreasedOFFSIDES
30Cytolytic hepatitisOFFSIDES
31Depressed Level of ConsciousnessOFFSIDES
32Depressive disorder622219CTD
33DiarrheaOFFSIDES
34Disorders of Excessive Somnolence10776750CTD
35DrowsinessOFFSIDES
36DysgraphiaOFFSIDES
37Dyskinesia, Drug-Induced944394
11222455		CTD
38DysuriaOFFSIDES
39Excessive masturbationOFFSIDES
40Excessive sexual fantasiesOFFSIDES
41Eye painOFFSIDES
42Facial NeuralgiaOFFSIDES
43Fatty LiverOFFSIDES
44Febrile bone marrow aplasiaOFFSIDES
45Flight of ideasOFFSIDES
46GamblingOFFSIDES
47Gamma-Glutamyltransferase IncreasedOFFSIDES
48Gastric ulcer helicobacterOFFSIDES
49General physical conditionOFFSIDES
50General physical health deteriorationOFFSIDES
51Glasgow coma scaleOFFSIDES
52GranulocytosisOFFSIDES
53Hallucinations, mixedOFFSIDES
54Hallucinations622219
944394		CTD
55Headache326325CTD
56Histrionic Personality DisorderOFFSIDES
57HomosexualityOFFSIDES
58IncoherentOFFSIDES
59Intention tremorOFFSIDES
60LipaseOFFSIDES
61Middle insomniaOFFSIDES
62MonoparesisOFFSIDES
63Motor retardationOFFSIDES
64Multiple drug overdoseOFFSIDES
65MutismOFFSIDES
66MyopericarditisOFFSIDES
67Nasal mucosal disorderOFFSIDES
68Nausea1091122CTD
OFFSIDES
69Ocular HypertensionOFFSIDES
70Ocular icterusOFFSIDES
71OverdoseOFFSIDES
72PallorOFFSIDES
73Parkinson Disease

View details

944394
1091122
10776750
12614313
 		CTD
74Parkinsonian Disorders11222455CTD
75Pericardial effusionOFFSIDES
76PericarditisOFFSIDES
77Protein total decreasedOFFSIDES
78Psychomotor skills impairedOFFSIDES
79Psychoses, Substance-Induced622219CTD
80RhinalgiaOFFSIDES
81Schizophrenia103114CTD
82Status EpilepticusOFFSIDES
83Sudden deathOFFSIDES
84TheftOFFSIDES
85Therapy non-responderOFFSIDES
86Urinary tract infection pseudomonalOFFSIDES
87Vomiting326325CTD
88YawningOFFSIDES
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