Trimetrexate
(NOYPYLRCIDNJJB-UHFFFAOYSA-N)
Structure
- SMILES
- COc1cc(NCc2ccc3c(c2C)c(N)nc(n3)N)cc(c1OC)OC
- Type(s)
- Approved; Investigational
- ATC code(s)
- P01AX07
- Molecular Formula:
- C19H23N5O3
- Molecular Weight:
- 369.418
- Log P:
- 3.9759
- Hydrogen Bond Acceptor:
- 8
- Hydrogen Bond Donor:
- 3
- TPSA:
- 117.54
- CAS Number(s):
- 52128-35-5
Synonym(s)
1.
Trimetrexate
2.
CI-898
3.
JB-11
4.
NSC-249008
5.
NSC-328564
6.
Trimetrexate Hydrate
7.
Trimetrexate Monohydrate, Monoacetate
8.
CI 898
9.
CI898
10.
Hydrate, Trimetrexate
11.
JB 11
12.
JB11
13.
Monohydrate, Monoacetate Trimetrexate
14.
NSC 249008
15.
NSC 328564
16.
NSC249008
17.
NSC328564
External Link(s)
Adverse Drug Event(s)
| Name | Number of Reports | Reference(s) | Data Source | |
|---|---|---|---|---|
| 1 | Alanine Aminotransferase Increased | SIDER | ||
| 2 | Aspartate Aminotransferase Increased | SIDER | ||
| 3 | Asthenia | SIDER | ||
| 4 | Blood alkaline phosphatase increased | SIDER | ||
| 5 | Blood creatinine increased | SIDER | ||
| 6 | Dermatitis | SIDER | ||
| 7 | Diarrhea | 11863117 | CTD | |
| 8 | Electrolyte imbalance | SIDER | ||
| 9 | Fatigue | SIDER | ||
| 10 | Feeling abnormal | SIDER | ||
| 11 | Hepatotoxicity | SIDER | ||
| 12 | Leukopenia | 7896546 | CTD | |
| 13 | Nausea | SIDER | ||
| 14 | Neutropenia | SIDER | ||
| 15 | Pruritus | SIDER | ||
| 16 | Thrombocytopenia | 7896546 | CTD SIDER | |
| 17 | Vomiting | SIDER |
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