Ceftazidime
(NMVPEQXCMGEDNH-TZVUEUGBSA-N)
Structure
- SMILES
- O=C1[C@@H](NC(=O)/C(=N\OC(C(=O)O)(C)C)/c2csc(n2)N)[C@@H]2N1C(=C(CS2)C[n+]1ccccc1)C(=O)[O-].O.O.O.O.O
- Molecular Formula:
- C22H32N6O12S2
- Molecular Weight:
- 636.652
- Log P:
- -0.7107
- Hydrogen Bond Acceptor:
- 19
- Hydrogen Bond Donor:
- 8
- TPSA:
- 290.91
- CAS Number(s):
- 78439-06-2
Synonym(s)
1.
Ceftazidime
2.
Ceftazidime Anhydrous
3.
Ceftazidime Pentahydrate
4.
Fortaz
5.
Fortum
6.
GR-20263
7.
LY-139381
8.
Pyridinium, 1-((7-(((2-amino-4-thiazolyl)((1-carboxy-1-methylethoxy)imino)acetyl)amino)-2-carboxy-8-oxo-5-thia-1-azabicyclo(4.2.0)oct-2-en-3-yl)methyl)-, inner salt, pentahydrate, (6R-(6alpha,7beta(Z)))-
9.
Tazidime
10.
GR 20263
11.
GR20263
12.
LY 139381
13.
LY139381
External Link(s)
Adverse Drug Event(s)
| Name | Number of Reports | Reference(s) | Data Source | |
|---|---|---|---|---|
| 1 | Vomiting | FAERS: 9 Canada Vigilance: 1 | Canada Vigilance US FAERS | |
| 2 | Hypotension | FAERS: 8 | US FAERS | |
| 3 | Anaphylactic shock | FAERS: 7 | US FAERS | |
| 4 | Product quality issue | FAERS: 7 | US FAERS | |
| 5 | Malaise | FAERS: 6 | US FAERS | |
| 6 | Erythema | FAERS: 5 | US FAERS | |
| 7 | Cardiac Arrest | FAERS: 4 | US FAERS | |
| 8 | Chills | FAERS: 4 | US FAERS | |
| 9 | Hypersensitivity | FAERS: 4 | US FAERS | |
| 10 | Myoclonus | FAERS: 4 | US FAERS | |
| 11 | Nausea | FAERS: 4 Canada Vigilance: 1 | Canada Vigilance US FAERS | |
| 12 | Rash erythematous | FAERS: 4 | US FAERS | |
| 13 | Wheezing | FAERS: 4 | US FAERS | |
| 14 | Bradycardia | FAERS: 3 | US FAERS | |
| 15 | Cerebral atrophy | FAERS: 3 | US FAERS | |
| 16 | Cyanosis | FAERS: 3 | US FAERS | |
| 17 | Dementia | FAERS: 3 | US FAERS | |
| 18 | Drug ineffective | FAERS: 3 | US FAERS | |
| 19 | Incorrect route of drug administration | FAERS: 3 | US FAERS | |
| 20 | Myocardial Infarction | FAERS: 3 | US FAERS | |
| 21 | Pharmaceutical product complaint | FAERS: 3 | US FAERS | |
| 22 | Pruritus | FAERS: 3 | US FAERS | |
| 23 | Respiratory distress | FAERS: 3 | US FAERS | |
| 24 | Status Epilepticus | FAERS: 3 | US FAERS | |
| 25 | Accidental overdose | FAERS: 2 | US FAERS | |
| 26 | Altered state of consciousness | FAERS: 2 | US FAERS | |
| 27 | Blood alkaline phosphatase increased | FAERS: 2 | US FAERS | |
| 28 | Blood sodium increased | FAERS: 2 | US FAERS | |
| 29 | Blood urea increased | FAERS: 2 | US FAERS | |
| 30 | Chest Pain | FAERS: 2 | US FAERS | |
| 31 | Chest discomfort | FAERS: 2 | US FAERS | |
| 32 | Dehydration | FAERS: 2 | US FAERS | |
| 33 | Disorientation | FAERS: 2 Canada Vigilance: 1 | Canada Vigilance US FAERS | |
| 34 | Disseminated Intravascular Coagulation | FAERS: 2 | US FAERS | |
| 35 | Electrocardiogram abnormal | FAERS: 2 | US FAERS | |
| 36 | Flushing | FAERS: 2 | US FAERS | |
| 37 | Foaming at mouth | FAERS: 2 | US FAERS | |
| 38 | Gastritis | FAERS: 2 | US FAERS | |
| 39 | Idiosyncratic drug reaction | FAERS: 2 | US FAERS | |
| 40 | Neutropenia | FAERS: 2 | US FAERS | |
| 41 | Palpitations | FAERS: 2 | US FAERS | |
| 42 | Rales | FAERS: 2 | US FAERS | |
| 43 | Respiratory arrest | FAERS: 2 | US FAERS | |
| 44 | Toxic Epidermal Necrolysis | FAERS: 2 | US FAERS | |
| 45 | Urinary Incontinence | FAERS: 2 | US FAERS | |
| 46 | Adverse event | FAERS: 1 | US FAERS | |
| 47 | Agitation | FAERS: 1 Canada Vigilance: 1 | Canada Vigilance US FAERS | |
| 48 | Antibiotic level above therapeutic | FAERS: 1 | US FAERS | |
| 49 | Asterixis | FAERS: 1 | US FAERS | |
| 50 | Blood creatine increased | FAERS: 1 | US FAERS | |
| 51 | Blood creatinine decreased | FAERS: 1 | US FAERS | |
| 52 | Blood creatinine increased | FAERS: 1 | US FAERS | |
| 53 | Burning sensation | FAERS: 1 | US FAERS | |
| 54 | Cholestasis | FAERS: 1 | US FAERS | |
| 55 | Circumstance or information capable of leading to medication error | FAERS: 1 | US FAERS | |
| 56 | Clostridium colitis | FAERS: 1 | US FAERS | |
| 57 | Clostridium difficile infection | FAERS: 1 | US FAERS | |
| 58 | Crying | FAERS: 1 | US FAERS | |
| 59 | Culture urine positive | FAERS: 1 | US FAERS | |
| 60 | Depressed Level of Consciousness | FAERS: 1 | US FAERS | |
| 61 | Dizziness | FAERS: 1 | US FAERS | |
| 62 | Drug toxicity | FAERS: 1 | US FAERS | |
| 63 | Dysarthria | FAERS: 1 | US FAERS | |
| 64 | Electroencephalogram abnormal | FAERS: 1 | US FAERS | |
| 65 | Excoriation | FAERS: 1 | US FAERS | |
| 66 | Fatigue | FAERS: 1 | US FAERS | |
| 67 | Gastroenteritis | FAERS: 1 | US FAERS | |
| 68 | Gaze palsy | FAERS: 1 | US FAERS | |
| 69 | Infusion Site Extravasation | FAERS: 1 | US FAERS | |
| 70 | Medication Error | FAERS: 1 | US FAERS | |
| 71 | Mutism | FAERS: 1 | US FAERS | |
| 72 | Nystagmus | FAERS: 1 | US FAERS | |
| 73 | Overdose | FAERS: 1 | US FAERS | |
| 74 | Pallor | FAERS: 1 | US FAERS | |
| 75 | Pancytopenia | FAERS: 1 | US FAERS | |
| 76 | Pharmaceutical product counterfeit | FAERS: 1 | US FAERS | |
| 77 | Post procedural sepsis | FAERS: 1 | US FAERS | |
| 78 | Product packaging quantity issue | FAERS: 1 | US FAERS | |
| 79 | Respiratory Failure | FAERS: 1 | US FAERS | |
| 80 | Rhonchi | FAERS: 1 | US FAERS | |
| 81 | Seizure like phenomena | FAERS: 1 | US FAERS | |
| 82 | Somnolence | FAERS: 1 | US FAERS | |
| 83 | Swelling | FAERS: 1 | US FAERS | |
| 84 | Syncope | FAERS: 1 | US FAERS | |
| 85 | Tachycardia | FAERS: 1 | US FAERS | |
| 86 | Tonic clonic movements | FAERS: 1 | US FAERS | |
| 87 | Urinary tract infection | FAERS: 1 | US FAERS | |
| 88 | Urticaria | FAERS: 1 | US FAERS | |
| 89 | Weight decreased | FAERS: 1 | US FAERS | |
| 90 | nervous system disorder | FAERS: 1 | US FAERS | |
| 91 | Embolism | Canada Vigilance: 1 | Canada Vigilance | |
| 92 | Pain | Canada Vigilance: 1 | Canada Vigilance |
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