Pasireotide diaspartate
(NEEFMPSSNFRRNC-HQUONIRXSA-N)
Structure
- SMILES
- OC(=O)C[C@@H](C(=O)O)N.OC(=O)C[C@@H](C(=O)O)N.NCCCC[C@@H]1NC(=O)[C@H](NC(=O)[C@@H](NC(=O)[C@H]2N(C(=O)[C@@H](NC(=O)[C@@H](NC1=O)Cc1ccc(cc1)OCc1ccccc1)Cc1ccccc1)C[C@@H](C2)OC(=O)NCCN)c1ccccc1)Cc1c[nH]c2c1cccc2
- Molecular Formula:
- C66H80N12O17
- Molecular Weight:
- 1313.410
- Log P:
- 5.8885
- Hydrogen Bond Acceptor:
- 28
- Hydrogen Bond Donor:
- 15
- TPSA:
- 482.44
- CAS Number(s):
- 820232-50-6
Synonym(s)
1.
Pasireotide diaspartate
External Link(s)
Adverse Drug Event(s)
| Name | Number of Reports | Reference(s) | Data Source | |
|---|---|---|---|---|
| 1 | Abdominal Pain | SIDER | ||
| 2 | Alanine Aminotransferase Increased | Canada Vigilance: 1 | Canada Vigilance SIDER | |
| 3 | Alopecia | SIDER | ||
| 4 | Amylase increased | SIDER | ||
| 5 | Anger | Canada Vigilance: 1 | Canada Vigilance | |
| 6 | Anxiety | SIDER | ||
| 7 | Arthralgia | SIDER | ||
| 8 | Aspartate Aminotransferase Increased | Canada Vigilance: 1 | Canada Vigilance SIDER | |
| 9 | Asthenia | Canada Vigilance: 1 | Canada Vigilance SIDER | |
| 10 | Back Pain | SIDER | ||
| 11 | Blood amylase increased | SIDER | ||
| 12 | Blood glucose increased | Canada Vigilance: 1 | Canada Vigilance SIDER | |
| 13 | Chest Pain | Canada Vigilance: 1 | Canada Vigilance | |
| 14 | Cholelithiasis | SIDER | ||
| 15 | Constipation | SIDER | ||
| 16 | Cortisol decreased | Canada Vigilance: 1 | Canada Vigilance | |
| 17 | Cortisol increased | Canada Vigilance: 1 | Canada Vigilance | |
| 18 | Diabetes Mellitus | SIDER | ||
| 19 | Dizziness | Canada Vigilance: 1 | Canada Vigilance SIDER | |
| 20 | Drug ineffective | Canada Vigilance: 1 | Canada Vigilance | |
| 21 | Dry skin | SIDER | ||
| 22 | Epistaxis | Canada Vigilance: 1 | Canada Vigilance | |
| 23 | Fatigue | Canada Vigilance: 1 | Canada Vigilance SIDER | |
| 24 | Gamma-Glutamyltransferase Increased | SIDER | ||
| 25 | Gastrointestinal Pain | SIDER | ||
| 26 | Headache | SIDER | ||
| 27 | Hypotension | Canada Vigilance: 1 | Canada Vigilance SIDER | |
| 28 | Influenza | SIDER | ||
| 29 | Initial insomnia | Canada Vigilance: 1 | Canada Vigilance | |
| 30 | Injection Site Reaction | SIDER | ||
| 31 | Lipase increased | SIDER | ||
| 32 | Malaise | Canada Vigilance: 1 | Canada Vigilance | |
| 33 | Memory impairment | Canada Vigilance: 1 | Canada Vigilance | |
| 34 | Mood swings | Canada Vigilance: 1 | Canada Vigilance | |
| 35 | Musculoskeletal discomfort | SIDER | ||
| 36 | Myalgia | SIDER | ||
| 37 | Nasopharyngitis | SIDER | ||
| 38 | Nausea | Canada Vigilance: 2 | Canada Vigilance SIDER | |
| 39 | Pancytopenia | Canada Vigilance: 1 | Canada Vigilance | |
| 40 | Pericarditis | Canada Vigilance: 1 | Canada Vigilance | |
| 41 | Pruritus | SIDER | ||
| 42 | Psychiatric symptom | Canada Vigilance: 1 | Canada Vigilance | |
| 43 | Sinus bradycardia | SIDER | ||
| 44 | Stress | Canada Vigilance: 1 | Canada Vigilance | |
| 45 | Vertigo | SIDER | ||
| 46 | Vomiting | Canada Vigilance: 2 | Canada Vigilance SIDER |
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