MetaADEDB 2.0 @ LMMD
N-(4-(3-amino-1H-indazol-4-yl)phenyl)-N1-(2-fluoro-5-methylphenyl)urea
(MPVGZUGXCQEXTM-UHFFFAOYSA-N)
Structure
SMILES
O=C(Nc1cc(C)ccc1F)Nc1ccc(cc1)c1cccc2c1c(N)n[nH]2
Molecular Formula:
C21H18FN5O
Molecular Weight:
375.399
Log P:
5.6308
Hydrogen Bond Acceptor:
5
Hydrogen Bond Donor:
4
TPSA:
95.83
CAS Number(s):
796967-16-3
Synonym(s)
1.
N-(4-(3-amino-1H-indazol-4-yl)phenyl)-N1-(2-fluoro-5-methylphenyl)urea
2.
A 741439
3.
A-741439
4.
A741439
5.
ABT 869
6.
ABT-869
7.
ABT869
8.
RG 3635
9.
RG-3635
10.
RG3635
11.
linifanib
External Link(s)
MeSHC513486
PubChem Compound11485656
BindingDB21079
ChEBI91435
CHEMBLCHEMBL223360
IUPHAR/BPS Guide to PHARMACOLOGY5657
KEGGdr:D09635
Therapeutic Target DatabaseD0M9QZ
ZINC6718813
Adverse Drug Event(s)
NameNumber of ReportsReference(s)Data Source
1Urinary tract infectionFAERS: 2US FAERS
2Abdominal PainFAERS: 1US FAERS
3FatigueFAERS: 1US FAERS
4Musculoskeletal chest painFAERS: 1US FAERS
5NauseaFAERS: 1US FAERS
6PyelonephritisFAERS: 1US FAERS
7SepsisFAERS: 1US FAERS
8Skin toxicityFAERS: 1US FAERS
9SomnolenceFAERS: 1US FAERS
10ThrombocytopeniaFAERS: 1US FAERS
11Toxicity to various agentsFAERS: 1US FAERS
12VomitingFAERS: 1US FAERS
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