Cefepime
(LRAJHPGSGBRUJN-OMIVUECESA-N)
Structure
- SMILES
- CO/N=C(/c1csc(n1)N)\C(=O)N[C@@H]1C(=O)N2[C@@H]1SCC(=C2C(=O)O)C[N+]1(C)CCCC1.O.Cl.[Cl-]
- Molecular Formula:
- C19H28Cl2N6O6S2
- Molecular Weight:
- 571.498
- Log P:
- -1.3347
- Hydrogen Bond Acceptor:
- 13
- Hydrogen Bond Donor:
- 5
- TPSA:
- 209.98
- CAS Number(s):
- 123171-59-5
Synonym(s)
1.
Cefepime
2.
Axépim
3.
BMY 28142
4.
BMY-28142
5.
Cefepim
6.
Cefepime Hydrochloride
7.
Maxipime
8.
Quadrocef
9.
BMY28142
External Link(s)
| MeSH | D000077723 |
| PubChem Compound | 9959752 9571075 |
| ChEBI | 31368 |
| CHEMBL | CHEMBL1200962 |
| KEGG | cpd:C12557 dr:D01157 |
Adverse Drug Event(s)
| Name | Number of Reports | Reference(s) | Data Source | |
|---|---|---|---|---|
| 1 | Neutropenia | FAERS: 15 | US FAERS | |
| 2 | Epilepsy | FAERS: 8 | US FAERS | |
| 3 | Status Epilepticus | FAERS: 8 | US FAERS | |
| 4 | Acute kidney injury | FAERS: 4 | US FAERS | |
| 5 | Aphasia | FAERS: 4 | US FAERS | |
| 6 | Blood creatinine increased | FAERS: 4 | US FAERS | |
| 7 | Myoclonus | FAERS: 4 | US FAERS | |
| 8 | Asthenia | FAERS: 3 | US FAERS | |
| 9 | Disorientation | FAERS: 3 | US FAERS | |
| 10 | Electroencephalogram abnormal | FAERS: 3 | US FAERS | |
| 11 | Mental status changes | FAERS: 3 | US FAERS | |
| 12 | Pruritus | FAERS: 3 | US FAERS | |
| 13 | Stupor | FAERS: 3 | US FAERS | |
| 14 | Agitation | FAERS: 2 | US FAERS | |
| 15 | Depressed Level of Consciousness | FAERS: 2 | US FAERS | |
| 16 | Drug administration error | FAERS: 2 | US FAERS | |
| 17 | Hypotension | FAERS: 2 | US FAERS | |
| 18 | Swelling | FAERS: 2 | US FAERS | |
| 19 | Tremor | FAERS: 2 | US FAERS | |
| 20 | Urinary Retention | FAERS: 2 | US FAERS | |
| 21 | Urticaria | FAERS: 2 | US FAERS | |
| 22 | jaundice | FAERS: 2 | US FAERS | |
| 23 | Bilirubin conjugated increased | FAERS: 1 | US FAERS | |
| 24 | Blood urea increased | FAERS: 1 | US FAERS | |
| 25 | Central nervous system lesion | FAERS: 1 | US FAERS | |
| 26 | Clostridium difficile colitis | FAERS: 1 | US FAERS | |
| 27 | Drug ineffective | FAERS: 1 | US FAERS | |
| 28 | Dysgeusia | FAERS: 1 | US FAERS | |
| 29 | Erythema Multiforme | FAERS: 1 | US FAERS | |
| 30 | Headache | FAERS: 1 | US FAERS | |
| 31 | Hepatomegaly | FAERS: 1 | US FAERS | |
| 32 | Hepatotoxicity | FAERS: 1 | US FAERS | |
| 33 | Hypersensitivity | FAERS: 1 | US FAERS | |
| 34 | Incorrect dose administered | FAERS: 1 | US FAERS | |
| 35 | Lethargy | FAERS: 1 | US FAERS | |
| 36 | Maternal exposure during pregnancy | FAERS: 1 | US FAERS | |
| 37 | Medication Error | FAERS: 1 | US FAERS | |
| 38 | Nausea | FAERS: 1 | US FAERS | |
| 39 | Pneumonia | FAERS: 1 | US FAERS | |
| 40 | Psoas Abscess | FAERS: 1 | US FAERS | |
| 41 | Red man syndrome | FAERS: 1 | US FAERS | |
| 42 | Renal tubular necrosis | FAERS: 1 | US FAERS | |
| 43 | Sepsis | FAERS: 1 | US FAERS | |
| 44 | Toxicity to various agents | FAERS: 1 | US FAERS | |
| 45 | Unresponsive to stimuli | FAERS: 1 | US FAERS | |
| 46 | Urinary tract infection | FAERS: 1 | US FAERS | |
| 47 | Vomiting | FAERS: 1 | US FAERS |
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