MetaADEDB 2.0 @ LMMD
trilostane
(KVJXBPDAXMEYOA-CXANFOAXSA-N)
Structure
SMILES
N#CC1=C(O)[C@@H]2[C@]3([C@@](C1)(C)[C@H]1CC[C@]4([C@H]([C@@H]1CC3)CC[C@@H]4O)C)O2
Type(s)
Approved; Investigational; Vet_approved; Withdrawn
ATC code(s)
H02CA01
Molecular Formula:
C20H27NO3
Molecular Weight:
329.433
Log P:
3.4669
Hydrogen Bond Acceptor:
4
Hydrogen Bond Donor:
2
TPSA:
76.78
CAS Number(s):
13647-35-3
Synonym(s)
1.
trilostane
2.
4alpha,5-epoxy-17beta-hydroxy-3-oxoandrostane-2-carbonitrile
3.
Modrenal
4.
WIN 24,540
External Link(s)
MeSHC009954
PubChem Compound656583
BindingDB50247882
ChEBI32260
CHEMBLCHEMBL1200907
DrugBankDB01108
DrugCentral2746
IUPHAR/BPS Guide to PHARMACOLOGY6850
KEGGcpd:C12580
dr:D01180
Therapeutic Target DatabaseD03XOC
ZINC100038546
Adverse Drug Event(s)
NameNumber of ReportsReference(s)Data Source
1Cushing Syndrome19153526CTD
2Depressive disorder19117688
20981412		CTD
3Female Urogenital Diseases18397916CTD
Powered by :

Page last updated at 2020-05-25 10:01:57 (Asia/Shanghai) | You are visitor No. 120262

Copyright © 2019-2020 Laboratory of Molecular Modeling and Design, Shanghai Key Laboratory of New Drug Design, School of Pharmacy, East China University of Science and Technology. All rights reserved.