MetaADEDB 2.0 @ LMMD
flupirtine
(JUUFBMODXQKSTD-UHFFFAOYSA-N)
Structure
SMILES
CCOC(=O)Nc1ccc(nc1N)NCc1ccc(cc1)F
Type(s)
Investigational
ATC code(s)
N02BG07
Molecular Formula:
C15H17FN4O2
Molecular Weight:
304.319
Log P:
3.7106
Hydrogen Bond Acceptor:
6
Hydrogen Bond Donor:
3
TPSA:
89.27
CAS Number(s):
56995-20-1
Synonym(s)
1.
flupirtine
2.
D 9998
3.
D-9998
4.
Katadolon
5.
ethyl 2-amino-6-((p-fluorobenzyl)amino)-3-pyridinecarbamate
6.
flupirtin maleate
7.
flupirtine maleate (1:1)
External Link(s)
MeSHC034161
PubChem Compound53276
BindingDB81199
ChEBI94646
CHEMBLCHEMBL255044
DrugBankDB06623
DrugCentral1215
IUPHAR/BPS Guide to PHARMACOLOGY2598
KEGGdr:D07978
Therapeutic Target DatabaseD0SD9V
ZINC1473
Adverse Drug Event(s)
NameNumber of ReportsReference(s)Data Source
1Abdominal discomfortOFFSIDES
2AcanthomaOFFSIDES
3AdenocarcinomaOFFSIDES
4Alanine Aminotransferase IncreasedOFFSIDES
5AlopeciaOFFSIDES
6AnorexiaOFFSIDES
7AscitesOFFSIDES
8Aspiration PneumoniaOFFSIDES
9Atrial tachycardiaOFFSIDES
10Autoimmune thrombocytopeniaOFFSIDES
11Biliary dilatationOFFSIDES
12Blood creatinine increasedOFFSIDES
13Blood lactate dehydrogenase increasedOFFSIDES
14Blood pressure inadequately controlledOFFSIDES
15Catalepsy9185829CTD
16Cerebral artery occlusionOFFSIDES
17Chemical and Drug Induced Liver Injury10916496CTD
18Chest PainOFFSIDES
19CholangiolitisOFFSIDES
20Cholestasis10916496CTD
21ChromaturiaOFFSIDES
22Cytomegalovirus test positiveOFFSIDES
23DeafnessOFFSIDES
24DermatophytosisOFFSIDES
25Disease recurrenceOFFSIDES
26Dissociative AmnesiaOFFSIDES
27DizzinessOFFSIDES
28DrowsinessOFFSIDES
29Duodenal UlcerOFFSIDES
30DysgeusiaOFFSIDES
31DyspepsiaOFFSIDES
32DysphemiaOFFSIDES
33Dysthymic DisorderOFFSIDES
34Endoscopy abnormalOFFSIDES
35EnuresisOFFSIDES
36Epstein-Barr virus antibody positiveOFFSIDES
37Erosive gastritisOFFSIDES
38Fatty LiverOFFSIDES
39Gamma-Glutamyltransferase IncreasedOFFSIDES
40Gastric pH decreasedOFFSIDES
41Gastric ulcerOFFSIDES
42Gastrointestinal infectionOFFSIDES
43General physical health deteriorationOFFSIDES
44Helicobacter pylori identification test positiveOFFSIDES
45Hepatitis AOFFSIDES
46Hepatitis B antibody positiveOFFSIDES
47HepatitisOFFSIDES
48HepatotoxicityOFFSIDES
49Hyperalgesia18950446CTD
50HyperkeratosisOFFSIDES
51IncontinenceOFFSIDES
52Intentional misuseOFFSIDES
53LipaseOFFSIDES
54Mechanical ventilationOFFSIDES
55Mixed hepatocellular-cholestatic injuryOFFSIDES
56MononeuritisOFFSIDES
57MonoparesisOFFSIDES
58Multiple drug overdoseOFFSIDES
59NauseaOFFSIDES
60Pain18950446CTD
OFFSIDES
61PallorOFFSIDES
62Prescribed overdoseOFFSIDES
63SoporOFFSIDES
64Tinea PedisOFFSIDES
65TinnitusOFFSIDES
66Tooth LossOFFSIDES
67Transaminases increasedOFFSIDES
68Tremor4039152CTD
69Ultrasound abdomen abnormalOFFSIDES
70Urge IncontinenceOFFSIDES
71Ventricular FibrillationOFFSIDES
72Visual disturbanceOFFSIDES
73jaundice10916496CTD
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