MetaADEDB 2.0 @ LMMD
tianeptine
(JICJBGPOMZQUBB-UHFFFAOYSA-N)
Structure
SMILES
OC(=O)CCCCCCNC1c2ccccc2N(S(=O)(=O)c2c1ccc(c2)Cl)C
Type(s)
Investigational
ATC code(s)
N06AX14
Molecular Formula:
C21H25ClN2O4S
Molecular Weight:
436.952
Log P:
5.7293
Hydrogen Bond Acceptor:
6
Hydrogen Bond Donor:
2
TPSA:
95.09
CAS Number(s):
66981-73-5; 72797-41-2; 169293-31-6; 191172-75-5
Synonym(s)
1.
tianeptine
2.
(3-chloro-6-methyl-5,5-dioxo-6,11-dihydrodibenzo(c,f)(1,2)thiazepin-11-yl)-7-aminoheptanoic acid
3.
Stablon
4.
coaxil
5.
tianeptine, (+-)-isomer
6.
tianeptine, monosodium salt
7.
tianeptine, monosodium salt, (+-)-isomer
External Link(s)
MeSHC050504
PubChem Compound68870
ChEBI91749
CHEMBLCHEMBL1289110
DrugBankDB09289
DrugCentral2650
IUPHAR/BPS Guide to PHARMACOLOGY7558
KEGGdr:D02575
Therapeutic Target DatabaseD06CVT
Adverse Drug Event(s)
NameNumber of ReportsReference(s)Data Source
1Brain DeathFAERS: 1US FAERS
2Intentional product misuseFAERS: 1US FAERS
3Toxic leukoencephalopathyFAERS: 1US FAERS
4Abdominal PainOFFSIDES
5AgraphiaOFFSIDES
6ApneaOFFSIDES
7AppendicitisOFFSIDES
8AsterixisOFFSIDES
9Atrial tachycardiaOFFSIDES
10Bacterial test positiveOFFSIDES
11Basal cell carcinomaOFFSIDES
12Blood alkaline phosphatase increasedOFFSIDES
13Blood fibrinogen increasedOFFSIDES
14Blood glucose abnormalOFFSIDES
15Blood sodiumOFFSIDES
16Breast discomfortOFFSIDES
17Bronchial ObstructionOFFSIDES
18BronchopneumopathyOFFSIDES
19Cardiac DeathOFFSIDES
20Cardiac HypertrophyOFFSIDES
21CheilitisOFFSIDES
22Chemotherapeutic drug level increasedOFFSIDES
23CholangiolitisOFFSIDES
24ColitisOFFSIDES
25ConfabulationOFFSIDES
26Creatinine renal clearance decreasedOFFSIDES
27Cytolytic hepatitisOFFSIDES
28DehydrationOFFSIDES
29DiarrheaOFFSIDES
30DrowsinessOFFSIDES
31Drug dispensing errorOFFSIDES
32Duodenal perforationOFFSIDES
33EpilepsyOFFSIDES
34Escherichia infectionOFFSIDES
35Escherichia urinary tract infectionOFFSIDES
36Fatty Liver24469900CTD
37Febrile bone marrow aplasiaOFFSIDES
38Femoral arterial stenosisOFFSIDES
39Fine motor delayOFFSIDES
40Fluid replacementOFFSIDES
41General physical health deteriorationOFFSIDES
42GlioblastomaOFFSIDES
43GlobulinuriaOFFSIDES
44HemiparesisOFFSIDES
45HydrothoraxOFFSIDES
46HyperkeratosisOFFSIDES
47Incorrect dose administeredOFFSIDES
48Left atrial dilatationOFFSIDES
49Mucosal erosionOFFSIDES
50Multiple drug overdose intentionalOFFSIDES
51Neurological decompensationOFFSIDES
52Pancreatic NeoplasmOFFSIDES
53Post procedural infectionOFFSIDES
54Productive CoughOFFSIDES
55Prothrombin level decreasedOFFSIDES
56PsoriasisOFFSIDES
57Psychomotor skills impairedOFFSIDES
58Pulmonary toxicityOFFSIDES
59Pustular psoriasisOFFSIDES
60Radical prostatectomyOFFSIDES
61Reticulocyte count increasedOFFSIDES
62RhabdomyolysisOFFSIDES
63RhonchiOFFSIDES
64SubileusOFFSIDES
65Superficial ThrombophlebitisOFFSIDES
66Tongue bitingOFFSIDES
67Transaminases increasedOFFSIDES
68Unevaluable eventOFFSIDES
69Ventricular hyperkinesiaOFFSIDES
70Ventricular internal diameter abnormalOFFSIDES
Powered by :

Page last updated at 2020-05-25 10:01:57 (Asia/Shanghai) | You are visitor No. 120239

Copyright © 2019-2020 Laboratory of Molecular Modeling and Design, Shanghai Key Laboratory of New Drug Design, School of Pharmacy, East China University of Science and Technology. All rights reserved.