Sincalide
(IZTQOLKUZKXIRV-YRVFCXMDSA-N)
Structure
- SMILES
- CSCC[C@@H](C(=O)NCC(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N)Cc1ccccc1)CC(=O)O)CCSC)Cc1c[nH]c2c1cccc2)NC(=O)[C@@H](NC(=O)[C@H](CC(=O)O)N)Cc1ccc(cc1)OS(=O)(=O)O
- Type(s)
- Approved
- ATC code(s)
- V04CC03
- Molecular Formula:
- C49H62N10O16S3
- Molecular Weight:
- 1143.270
- Log P:
- 3.8883
- Hydrogen Bond Acceptor:
- 27
- Hydrogen Bond Donor:
- 13
- TPSA:
- 485.78
- CAS Number(s):
- 25126-32-3
Synonym(s)
1.
Sincalide
2.
CCK-8
3.
Cholecystokinin Octapeptide
4.
CCK-OP
5.
Cholecystokinin Pancreozymin C-Terminal Octapeptide
6.
H-Asp-Tyr(SO3H)-Met-Gly-Trp-Met-Asp-Phe-NH2
7.
Kinevac
8.
OP-CCK
9.
SQ-19,844
10.
SQ-19844
11.
Syncalide
12.
Cholecystokinin Pancreozymin C Terminal Octapeptide
13.
SQ 19,844
14.
SQ 19844
15.
SQ19,844
16.
SQ19844
External Link(s)
Adverse Drug Event(s)
| Name | Number of Reports | Reference(s) | Data Source | |
|---|---|---|---|---|
| 1 | Drug ineffective | FAERS: 17 | US FAERS | |
| 2 | No adverse event | FAERS: 17 | US FAERS | |
| 3 | Post procedural complication | FAERS: 5 | US FAERS | |
| 4 | Nausea | FAERS: 4 | SIDER US FAERS | |
| 5 | Chills | FAERS: 3 | US FAERS | |
| 6 | Fatigue | FAERS: 3 | US FAERS | |
| 7 | Abdominal discomfort | FAERS: 2 | SIDER US FAERS | |
| 8 | Expired product administered | FAERS: 2 | US FAERS | |
| 9 | Myalgia | FAERS: 2 | US FAERS | |
| 10 | Abdominal Pain | FAERS: 1 | SIDER US FAERS | |
| 11 | Accidental exposure to product | FAERS: 1 | US FAERS | |
| 12 | Accidental exposure | FAERS: 1 | US FAERS | |
| 13 | Asthenia | FAERS: 1 | US FAERS | |
| 14 | Candida test positive | FAERS: 1 | US FAERS | |
| 15 | Contrast media reaction | FAERS: 1 | US FAERS | |
| 16 | Discomfort | FAERS: 1 | SIDER US FAERS | |
| 17 | Dizziness | FAERS: 1 | SIDER US FAERS | |
| 18 | Extravasation | FAERS: 1 | US FAERS | |
| 19 | Eye pain | FAERS: 1 | US FAERS | |
| 20 | Feeling abnormal | FAERS: 1 | US FAERS | |
| 21 | Flushing | FAERS: 1 | SIDER US FAERS | |
| 22 | Headache | FAERS: 1 | SIDER US FAERS | |
| 23 | Hepatobiliary scan abnormal | FAERS: 1 | US FAERS | |
| 24 | Injection site erythema | FAERS: 1 | US FAERS | |
| 25 | Laboratory test interference | FAERS: 1 | US FAERS | |
| 26 | Laryngospasm | FAERS: 1 | US FAERS | |
| 27 | Malaise | FAERS: 1 | US FAERS | |
| 28 | Medication Error | FAERS: 1 | US FAERS | |
| 29 | Mydriasis | FAERS: 1 | US FAERS | |
| 30 | Pain | FAERS: 1 | SIDER US FAERS | |
| 31 | Pelvic fluid collection | FAERS: 1 | US FAERS | |
| 32 | Pregnancy | FAERS: 1 | US FAERS | |
| 33 | Product closure issue | FAERS: 1 | US FAERS | |
| 34 | Product label issue | FAERS: 1 | US FAERS | |
| 35 | Product use issue | FAERS: 1 | US FAERS | |
| 36 | Supraventricular tachycardia | FAERS: 1 | US FAERS | |
| 37 | Swelling | FAERS: 1 | US FAERS | |
| 38 | Tachycardia | FAERS: 1 | US FAERS | |
| 39 | Tremor | FAERS: 1 Canada Vigilance: 1 | Canada Vigilance US FAERS | |
| 40 | Vascular rupture | FAERS: 1 | US FAERS | |
| 41 | White blood cell count decreased | FAERS: 1 | US FAERS | |
| 42 | Wrong drug administered | FAERS: 1 | US FAERS | |
| 43 | Abdominal Cramps | SIDER | ||
| 44 | Amnesia | 24309294 | CTD | |
| 45 | Anorexia | 15879057 | CTD | |
| 46 | Delayed gastric emptying | SIDER | ||
| 47 | Dermatitis | SIDER | ||
| 48 | Erythema Multiforme | Canada Vigilance: 1 | Canada Vigilance | |
| 49 | Erythema | Canada Vigilance: 2 | Canada Vigilance SIDER | |
| 50 | Hypersensitivity | SIDER | ||
| 51 | Hypotension | SIDER | ||
| 52 | Impaired gastric emptying | SIDER | ||
| 53 | Lightheadedness | SIDER | ||
| 54 | Lip swelling | Canada Vigilance: 1 | Canada Vigilance | |
| 55 | Mouth swelling | Canada Vigilance: 1 | Canada Vigilance | |
| 56 | Numbness | SIDER | ||
| 57 | Seizures | 6316193 | CTD | |
| 58 | Shock | SIDER | ||
| 59 | Sneezing | SIDER | ||
| 60 | Stomach ache | SIDER | ||
| 61 | Sweating | SIDER | ||
| 62 | Syncope | SIDER | ||
| 63 | Urticaria | Canada Vigilance: 2 | Canada Vigilance | |
| 64 | Vomiting | SIDER |
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