Terazosin
(IWSWDOUXSCRCKW-UHFFFAOYSA-N)
Structure
- SMILES
- COc1cc2nc(nc(c2cc1OC)N)N1CCN(CC1)C(=O)C1CCCO1.Cl
- Molecular Formula:
- C19H26ClN5O4
- Molecular Weight:
- 423.894
- Log P:
- 2.4429
- Hydrogen Bond Acceptor:
- 9
- Hydrogen Bond Donor:
- 2
- TPSA:
- 103.04
- CAS Number(s):
- 63074-08-8
Synonym(s)
1.
Terazosin
2.
A 45975
3.
Adecur
4.
Apo-Terazosin
5.
Deflox
6.
Dysalfa
7.
Flotrin
8.
Heitrin
9.
Hytrin
10.
Hytrin BPH
11.
Hytrine
12.
Magnurol
13.
Novo-Terazosin
14.
Nu-Terazosin
15.
PMS-Terazosin
16.
Sutif
17.
Tazusin
18.
Terazoflo
19.
Terazosin AZU
20.
Terazosin Hexal
21.
Terazosin hydrochloride
22.
Terazosina Alter
23.
Terazosina Kern
24.
Terazosina Qualix
25.
Zayasel
26.
ratio-Terazosin
27.
terazosin hydrochloride anhydrous
28.
terazosin, monohydrochloride, dihydrate
External Link(s)
| MeSH | C041226 |
| PubChem Compound | 135958608 44383 663211 |
| CHEMBL | CHEMBL1256665 |
Adverse Drug Event(s)
| Name | Number of Reports | Reference(s) | Data Source | |
|---|---|---|---|---|
| 1 | Drug ineffective | FAERS: 22 | US FAERS | |
| 2 | Dizziness | FAERS: 15 Canada Vigilance: 1 | Canada Vigilance US FAERS | |
| 3 | Syncope | FAERS: 10 | US FAERS | |
| 4 | Nausea | FAERS: 8 | US FAERS | |
| 5 | Hypotension | FAERS: 7 | US FAERS | |
| 6 | Headache | FAERS: 6 Canada Vigilance: 1 | Canada Vigilance US FAERS | |
| 7 | Dysuria | FAERS: 5 | US FAERS | |
| 8 | Asthenia | FAERS: 4 | US FAERS | |
| 9 | Therapeutic response unexpected with drug substitution | FAERS: 4 | US FAERS | |
| 10 | Fatigue | FAERS: 3 | US FAERS | |
| 11 | Gastroenteritis | FAERS: 3 | US FAERS | |
| 12 | Nocturia | FAERS: 3 | US FAERS | |
| 13 | Pharmaceutical product complaint | FAERS: 3 | US FAERS | |
| 14 | Priapism | FAERS: 3 | US FAERS | |
| 15 | Urticaria | FAERS: 3 | US FAERS | |
| 16 | Abdominal discomfort | FAERS: 2 | US FAERS | |
| 17 | Epistaxis | FAERS: 2 | US FAERS | |
| 18 | Erectile dysfunction | FAERS: 2 | US FAERS | |
| 19 | Feeling abnormal | FAERS: 2 | US FAERS | |
| 20 | Lip swelling | FAERS: 2 | US FAERS | |
| 21 | Medication Error | FAERS: 2 | US FAERS | |
| 22 | Overdose | FAERS: 2 | US FAERS | |
| 23 | Pain | FAERS: 2 | US FAERS | |
| 24 | Presyncope | FAERS: 2 | US FAERS | |
| 25 | Pruritus | FAERS: 2 | US FAERS | |
| 26 | Therapy non-responder | FAERS: 2 | US FAERS | |
| 27 | Tremor | FAERS: 2 | US FAERS | |
| 28 | Unevaluable event | FAERS: 2 | US FAERS | |
| 29 | Accidental drug intake by child | FAERS: 1 | US FAERS | |
| 30 | Alopecia | FAERS: 1 | US FAERS | |
| 31 | Amaurosis | FAERS: 1 | US FAERS | |
| 32 | Angioedema | FAERS: 1 | US FAERS | |
| 33 | Anuria | FAERS: 1 | US FAERS | |
| 34 | Anxiety | FAERS: 1 | US FAERS | |
| 35 | Arthralgia | FAERS: 1 | US FAERS | |
| 36 | Asphyxia | FAERS: 1 | US FAERS | |
| 37 | Blood creatine phosphokinase increased | FAERS: 1 | US FAERS | |
| 38 | Blood pressure inadequately controlled | FAERS: 1 | US FAERS | |
| 39 | Blood urine present | FAERS: 1 | US FAERS | |
| 40 | Cardiac Arrest | FAERS: 1 | US FAERS | |
| 41 | Chest discomfort | FAERS: 1 | US FAERS | |
| 42 | Chills | FAERS: 1 | US FAERS | |
| 43 | Concomitant disease aggravated | FAERS: 1 | US FAERS | |
| 44 | Depressed Level of Consciousness | FAERS: 1 | US FAERS | |
| 45 | Drug dispensing error | FAERS: 1 | US FAERS | |
| 46 | Expired drug administered | FAERS: 1 | US FAERS | |
| 47 | Eye irritation | FAERS: 1 | US FAERS | |
| 48 | Feeling Cold | FAERS: 1 | US FAERS | |
| 49 | Feeling jittery | FAERS: 1 | US FAERS | |
| 50 | Flatulence | FAERS: 1 | US FAERS | |
| 51 | Incorrect dose administered | FAERS: 1 | US FAERS | |
| 52 | Left Ventricular Hypertrophy | FAERS: 1 | US FAERS | |
| 53 | Limb injury | FAERS: 1 | US FAERS | |
| 54 | Macular degeneration | FAERS: 1 | US FAERS | |
| 55 | Medication residue | FAERS: 1 | US FAERS | |
| 56 | Meningioma | FAERS: 1 | US FAERS | |
| 57 | Myalgia | FAERS: 1 | US FAERS | |
| 58 | Night sweats | FAERS: 1 | US FAERS | |
| 59 | Non-cardiac chest pain | FAERS: 1 | US FAERS | |
| 60 | Palpitations | FAERS: 1 | US FAERS | |
| 61 | Personality Change | FAERS: 1 | US FAERS | |
| 62 | Pneumonia | FAERS: 1 | US FAERS | |
| 63 | Product quality issue | FAERS: 1 | US FAERS | |
| 64 | Product substitution issue | FAERS: 1 | US FAERS | |
| 65 | Prostatic Obstruction | FAERS: 1 | US FAERS | |
| 66 | Respiratory distress | FAERS: 1 | US FAERS | |
| 67 | Restlessness | FAERS: 1 | US FAERS | |
| 68 | Scleroderma | FAERS: 1 | US FAERS | |
| 69 | Screaming | FAERS: 1 | US FAERS | |
| 70 | Sluggishness | FAERS: 1 | US FAERS | |
| 71 | Somnolence | FAERS: 1 | US FAERS | |
| 72 | Therapy cessation | FAERS: 1 | US FAERS | |
| 73 | Therapy regimen changed | FAERS: 1 | US FAERS | |
| 74 | Tooth Loss | FAERS: 1 | US FAERS | |
| 75 | Unresponsive to stimuli | FAERS: 1 | US FAERS | |
| 76 | Urinary Incontinence | FAERS: 1 Canada Vigilance: 1 | Canada Vigilance US FAERS | |
| 77 | Urinary hesitation | FAERS: 1 | US FAERS | |
| 78 | Urinary tract infection | FAERS: 1 | US FAERS | |
| 79 | Visual Impairment | FAERS: 1 | US FAERS | |
| 80 | Vomiting | FAERS: 1 | US FAERS | |
| 81 | White blood cell count decreased | FAERS: 1 | US FAERS | |
| 82 | Anaphylactoid Reaction | Canada Vigilance: 1 | Canada Vigilance | |
| 83 | Atrioventricular Block | Canada Vigilance: 2 | Canada Vigilance | |
| 84 | Bronchospasm | Canada Vigilance: 1 | Canada Vigilance | |
| 85 | Chest Pain | Canada Vigilance: 1 | Canada Vigilance | |
| 86 | Electrocardiogram abnormal | Canada Vigilance: 2 | Canada Vigilance | |
| 87 | Lethargy | Canada Vigilance: 1 | Canada Vigilance | |
| 88 | Musculoskeletal Pain | Canada Vigilance: 1 | Canada Vigilance | |
| 89 | Neck Pain | Canada Vigilance: 1 | Canada Vigilance | |
| 90 | Oropharyngeal pain | Canada Vigilance: 1 | Canada Vigilance | |
| 91 | Vasculitis | Canada Vigilance: 1 | Canada Vigilance |
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