MetaADEDB 2.0 @ LMMD
istradefylline
(IQVRBWUUXZMOPW-PKNBQFBNSA-N)
Structure
SMILES
COc1cc(/C=C/c2nc3c(n2C)c(=O)n(c(=O)n3CC)CC)ccc1OC
Type(s)
Investigational
Molecular Formula:
C20H24N4O4
Molecular Weight:
384.429
Log P:
2.1241
Hydrogen Bond Acceptor:
8
Hydrogen Bond Donor:
0
TPSA:
80.28
CAS Number(s):
155270-99-8
Synonym(s)
1.
istradefylline
2.
8-(2-(3,4-dimethoxyphenyl)ethenyl)-1,3-diethyl-3,7-dihydro-7-methyl-1H-purine-2,6-dione
3.
KW 6002
4.
KW-6002
External Link(s)
MeSHC111599
PubChem Compound5311037
BindingDB50176050
ChEBI134726
CHEMBLCHEMBL431770
DrugBankDB11757
DrugCentral4882
IUPHAR/BPS Guide to PHARMACOLOGY5608
KEGGdr:D04641
Therapeutic Target DatabaseD0F4ZY
ZINC3803921
Adverse Drug Event(s)
NameNumber of ReportsReference(s)Data Source
1Basal Ganglia Diseases18594798CTD
2Brain Ischemia15111244CTD
3Catalepsy10591873
15111244		CTD
4Dyskinesia, Drug-Induced14637099
17192438		CTD
5Hypokinesia10591873CTD
6Muscle Rigidity15111244CTD
7Parkinson Disease21210664CTD
8Parkinsonian Disorders

View details

10739638
12614340
14637099
15899244
27297283
 		CTD
9Tremor18508458
19467297		CTD
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