Raltegravir Potassium
(IFUKBHBISRAZTF-UHFFFAOYSA-M)
Structure
- SMILES
- Fc1ccc(cc1)CNC(=O)c1nc(n(c(=O)c1[O-])C)C(NC(=O)c1nnc(o1)C)(C)C.[K+]
- Molecular Formula:
- C20H20FKN6O5
- Molecular Weight:
- 482.507
- Log P:
- 2.1315
- Hydrogen Bond Acceptor:
- 11
- Hydrogen Bond Donor:
- 2
- TPSA:
- 155.07
- CAS Number(s):
- 871038-72-1
Synonym(s)
1.
Raltegravir Potassium
2.
Isentress
3.
MK 0518
4.
MK-0518
5.
MK0518
6.
Raltegravir
7.
0518, MK
8.
Potassium, Raltegravir
External Link(s)
| MeSH | D000068898 |
| PubChem Compound | 23668479 135800706 |
| CHEMBL | CHEMBL518520 |
| KEGG | dr:D07133 |
Adverse Drug Event(s)
| Name | Number of Reports | Reference(s) | Data Source | |
|---|---|---|---|---|
| 1 | Pathogen resistance | FAERS: 5 | US FAERS | |
| 2 | Adverse event | FAERS: 2 | US FAERS | |
| 3 | Hepatotoxicity | FAERS: 2 | US FAERS | |
| 4 | Amylase increased | FAERS: 1 | US FAERS | |
| 5 | Blood creatine increased | FAERS: 1 | US FAERS | |
| 6 | Blood creatine phosphokinase increased | FAERS: 1 | US FAERS | |
| 7 | Congenital Hydrocephalus | FAERS: 1 | US FAERS | |
| 8 | Deafness | FAERS: 1 | US FAERS | |
| 9 | Dementia | FAERS: 1 | US FAERS | |
| 10 | Drug dose omission | FAERS: 1 | US FAERS | |
| 11 | Drug exposure during pregnancy | FAERS: 1 | US FAERS | |
| 12 | Drug ineffective | FAERS: 1 | US FAERS | |
| 13 | Drug resistance | FAERS: 1 | US FAERS | |
| 14 | Ectopic kidney | FAERS: 1 | US FAERS | |
| 15 | Lipase increased | FAERS: 1 | US FAERS | |
| 16 | Lower respiratory tract infection | FAERS: 1 | US FAERS | |
| 17 | Lymphoma | FAERS: 1 | US FAERS | |
| 18 | Myalgia | FAERS: 1 | US FAERS | |
| 19 | Myositis | FAERS: 1 | US FAERS | |
| 20 | Pneumonia | FAERS: 1 | US FAERS | |
| 21 | Presyncope | FAERS: 1 | US FAERS | |
| 22 | Product use in unapproved indication | FAERS: 1 | US FAERS | |
| 23 | Product use issue | FAERS: 1 | US FAERS | |
| 24 | Rhabdomyolysis | FAERS: 1 | US FAERS | |
| 25 | Stevens-Johnson Syndrome | FAERS: 1 | 25811541 | CTD US FAERS |
| 26 | Tuberculosis | FAERS: 1 | US FAERS | |
| 27 | treatment failure | FAERS: 1 | US FAERS | |
| 28 | HIV Infections | 21128663 22371894 | CTD |
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