MetaADEDB: Drug

MetaADEDB 2.0 @ LMMD

pimobendan

(GLBJJMFZWDBELO-UHFFFAOYSA-N)

Structure

SMILES: COc1ccc(cc1)c1nc2c([nH]1)cc(cc2)C1=NNC(=O)CC1C
Type(s): Vet_approved
Molecular Formula:: C19H18N4O2
Molecular Weight:: 334.372
Log P:: 2.8630
Hydrogen Bond Acceptor:: 5
Hydrogen Bond Donor:: 2
TPSA:: 79.37
CAS Number(s):: 74150-27-9; 118428-36-7; 118428-37-8; 118428-38-9

Synonym(s)

pimobendan

4,5-dihydro-6-(2-(4-methoxyphenyl)-1H-benzimidazole-5-yl)-5-methyl-3(2H)-pyridazinone

UD CG 115

UD-CG 115

UD-CG115

pimobendane

External Link(s)

MeSH	C041648
PubChem Compound	4823
BindingDB	50282617
ChEBI	32003
CHEMBL	CHEMBL24646
DrugBank	DB11450
DrugCentral	2171
KEGG	dr:D01133

Adverse Drug Event(s)

	Name	Reference(s)	Data Source
1	Acute respiratory failure		OFFSIDES
2	Altered state of consciousness		OFFSIDES
3	Anorexia		OFFSIDES
4	Apathy		OFFSIDES
5	Asphyxia		OFFSIDES
6	Asthma		OFFSIDES
7	Blood alkaline phosphatase increased		OFFSIDES
8	Blood creatine phosphokinase increased		OFFSIDES
9	Blood creatinine increased		OFFSIDES
10	Blood glucose decreased		OFFSIDES
11	Blood lactate dehydrogenase increased		OFFSIDES
12	Blood urea increased		OFFSIDES
13	Blood uric acid		OFFSIDES
14	Brain natriuretic peptide increased		OFFSIDES
15	Cardiomegaly	17556660	CTD
16	Cardiomyopathy, Dilated	17556660 20428258	CTD
17	Cardiotoxicity		OFFSIDES
18	Cardiovirus Infections	10193745	CTD
19	Catheter related infection		OFFSIDES
20	Cold sweat		OFFSIDES
21	Congenital tricuspid valve incompetence		OFFSIDES
22	Cortical laminar necrosis		OFFSIDES
23	Demyelination		OFFSIDES
24	Dizziness		OFFSIDES
25	Dyslalia		OFFSIDES
26	Ejection Fraction Decreased		OFFSIDES
27	Embolism		OFFSIDES
28	Eosinophilic myocarditis		OFFSIDES
29	Erythropenia		OFFSIDES
30	Escherichia infection		OFFSIDES
31	Esophageal Stenosis		OFFSIDES
32	Feeling abnormal		OFFSIDES
33	Gastric adenoma		OFFSIDES
34	Gastric mucosal lesion		OFFSIDES
35	Gastric ulcer		OFFSIDES
36	Gastrointestinal hypomotility		OFFSIDES
37	Hepatic congestion		OFFSIDES
38	Hypertensive heart disease		OFFSIDES
39	Hypoxia		OFFSIDES
40	Implantable defibrillator insertion		OFFSIDES
41	Incorrect dose administered		OFFSIDES
42	Infection		OFFSIDES
43	Infusion site mobility decreased		OFFSIDES
44	Leukopenia neonatal		OFFSIDES
45	Mechanical ventilation		OFFSIDES
46	Myeloblastoma		OFFSIDES
47	Myelodysplasia		OFFSIDES
48	Myocarditis	10193745	CTD
49	Nerve Block		OFFSIDES
50	Orthopnea		OFFSIDES
51	PCO2 decreased		OFFSIDES
52	PO2 decreased		OFFSIDES
53	Pericarditis		OFFSIDES
54	Physical examination abnormal		OFFSIDES
55	Pulmonary Hypertension		OFFSIDES
56	Pulmonary congestion		OFFSIDES
57	Renal cyst		OFFSIDES
58	Sclerosing encapsulating peritonitis		OFFSIDES
59	Ventricular Fibrillation		OFFSIDES
60	Yawning		OFFSIDES

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