Janumet XR
(GCERFBKFVDLDKD-NRYJBHHQSA-N)
Structure
- SMILES
- OP(=O)(O)O.CN(C(=N)N=C(N)N)C.N[C@H](Cc1cc(F)c(cc1F)F)CC(=O)N1CCn2c(C1)nnc2C(F)(F)F.Cl
- Molecular Formula:
- C20H30ClF6N10O5P
- Molecular Weight:
- 670.933
- Log P:
- 2.7846
- Hydrogen Bond Acceptor:
- 15
- Hydrogen Bond Donor:
- 8
- TPSA:
- 256.1
- CAS Number(s):
- 1011232-08-8
Synonym(s)
1.
Janumet XR
External Link(s)
| PubChem Compound | 24848107 |
Adverse Drug Event(s)
| Name | Number of Reports | Reference(s) | Data Source | |
|---|---|---|---|---|
| 1 | Inappropriate schedule of drug administration | FAERS: 90 | US FAERS | |
| 2 | No adverse event | FAERS: 82 | US FAERS | |
| 3 | Blood glucose increased | FAERS: 57 Canada Vigilance: 1 | Canada Vigilance US FAERS | |
| 4 | Drug ineffective | FAERS: 47 Canada Vigilance: 2 | Canada Vigilance US FAERS | |
| 5 | Drug dose omission | FAERS: 37 | US FAERS | |
| 6 | Nausea | FAERS: 37 Canada Vigilance: 2 | Canada Vigilance US FAERS | |
| 7 | Product quality issue | FAERS: 36 Canada Vigilance: 1 | Canada Vigilance US FAERS | |
| 8 | Medication residue present | FAERS: 31 | US FAERS | |
| 9 | Pancreatitis | FAERS: 27 Canada Vigilance: 2 | Canada Vigilance US FAERS | |
| 10 | Vomiting | FAERS: 20 | US FAERS | |
| 11 | Adverse event | FAERS: 19 | US FAERS | |
| 12 | Abdominal discomfort | FAERS: 18 | US FAERS | |
| 13 | Malaise | FAERS: 17 | US FAERS | |
| 14 | Product dose omission | FAERS: 16 Canada Vigilance: 1 | Canada Vigilance US FAERS | |
| 15 | Blood glucose abnormal | FAERS: 15 | US FAERS | |
| 16 | Abdominal Pain | FAERS: 14 | US FAERS | |
| 17 | Diabetes mellitus inadequate control | FAERS: 13 Canada Vigilance: 1 | Canada Vigilance US FAERS | |
| 18 | Dizziness | FAERS: 12 Canada Vigilance: 2 | Canada Vigilance US FAERS | |
| 19 | Fatigue | FAERS: 12 Canada Vigilance: 1 | Canada Vigilance US FAERS | |
| 20 | Headache | FAERS: 12 Canada Vigilance: 2 | Canada Vigilance US FAERS | |
| 21 | Circumstance or information capable of leading to medication error | FAERS: 10 | US FAERS | |
| 22 | Feeling abnormal | FAERS: 9 | US FAERS | |
| 23 | Blood glucose decreased | FAERS: 8 | US FAERS | |
| 24 | Drug prescribing error | FAERS: 8 | US FAERS | |
| 25 | Dyspepsia | FAERS: 8 | US FAERS | |
| 26 | Arthralgia | FAERS: 7 | US FAERS | |
| 27 | Asthenia | FAERS: 7 | US FAERS | |
| 28 | Constipation | FAERS: 7 | US FAERS | |
| 29 | Product physical issue | FAERS: 7 | US FAERS | |
| 30 | Product use issue | FAERS: 7 | US FAERS | |
| 31 | Weight decreased | FAERS: 7 | US FAERS | |
| 32 | Wrong technique in product usage process | FAERS: 7 | US FAERS | |
| 33 | Epistaxis | FAERS: 6 | US FAERS | |
| 34 | Erectile dysfunction | FAERS: 6 | US FAERS | |
| 35 | Myalgia | FAERS: 6 | US FAERS | |
| 36 | Pain | FAERS: 6 | US FAERS | |
| 37 | Pancreatic carcinoma | FAERS: 6 | US FAERS | |
| 38 | Product packaging quantity issue | FAERS: 6 | US FAERS | |
| 39 | Urticaria | FAERS: 6 | US FAERS | |
| 40 | Visual Impairment | FAERS: 6 | US FAERS | |
| 41 | Inappropriate schedule of product administration | FAERS: 5 | US FAERS | |
| 42 | Overdose | FAERS: 5 | US FAERS | |
| 43 | Tremor | FAERS: 5 | US FAERS | |
| 44 | Alopecia | FAERS: 4 | US FAERS | |
| 45 | Angioedema | FAERS: 4 | US FAERS | |
| 46 | Blood creatinine increased | FAERS: 4 | US FAERS | |
| 47 | Chest discomfort | FAERS: 4 | US FAERS | |
| 48 | Expired product administered | FAERS: 4 | US FAERS | |
| 49 | Lipase increased | FAERS: 4 | US FAERS | |
| 50 | Medication Error | FAERS: 4 | US FAERS | |
| 51 | Medication residue | FAERS: 4 | US FAERS | |
| 52 | Nasopharyngitis | FAERS: 4 | US FAERS | |
| 53 | Peripheral swelling | FAERS: 4 | US FAERS | |
| 54 | Prescribed underdose | FAERS: 4 | US FAERS | |
| 55 | Blood glucose fluctuation | FAERS: 3 | US FAERS | |
| 56 | Cholelithiasis | FAERS: 3 | US FAERS | |
| 57 | Drug administration error | FAERS: 3 | US FAERS | |
| 58 | Drug effect incomplete | FAERS: 3 | US FAERS | |
| 59 | Dysgeusia | FAERS: 3 | US FAERS | |
| 60 | Flatulence | FAERS: 3 | US FAERS | |
| 61 | Incorrect dose administered | FAERS: 3 | US FAERS | |
| 62 | Myocardial Infarction | FAERS: 3 | US FAERS | |
| 63 | Poor quality product administered | FAERS: 3 | US FAERS | |
| 64 | Product solubility abnormal | FAERS: 3 | US FAERS | |
| 65 | Somnolence | FAERS: 3 | US FAERS | |
| 66 | Therapeutic response unexpected | FAERS: 3 | US FAERS | |
| 67 | Thrombocytopenia | FAERS: 3 | US FAERS | |
| 68 | Vertigo | FAERS: 3 | US FAERS | |
| 69 | Wrong technique in drug usage process | FAERS: 3 | US FAERS | |
| 70 | Amylase increased | FAERS: 2 | US FAERS | |
| 71 | Burning sensation | FAERS: 2 | US FAERS | |
| 72 | Chest Pain | FAERS: 2 Canada Vigilance: 1 | Canada Vigilance US FAERS | |
| 73 | Chromaturia | FAERS: 2 | US FAERS | |
| 74 | Diabetic Retinopathy | FAERS: 2 | US FAERS | |
| 75 | Drug dispensing error | FAERS: 2 | US FAERS | |
| 76 | Dysarthria | FAERS: 2 | US FAERS | |
| 77 | Erythema | FAERS: 2 | US FAERS | |
| 78 | Eye pain | FAERS: 2 | US FAERS | |
| 79 | Genital rash | FAERS: 2 | US FAERS | |
| 80 | Hernia | FAERS: 2 | US FAERS | |
| 81 | Hypersensitivity | FAERS: 2 | US FAERS | |
| 82 | Infrequent bowel movements | FAERS: 2 | US FAERS | |
| 83 | Intentional product misuse | FAERS: 2 | US FAERS | |
| 84 | Joint swelling | FAERS: 2 | US FAERS | |
| 85 | Memory impairment | FAERS: 2 Canada Vigilance: 1 | Canada Vigilance US FAERS | |
| 86 | Metabolic acidosis | FAERS: 2 | US FAERS | |
| 87 | Neck Pain | FAERS: 2 | US FAERS | |
| 88 | Nervousness | FAERS: 2 | US FAERS | |
| 89 | Night sweats | FAERS: 2 | US FAERS | |
| 90 | Palpitations | FAERS: 2 | US FAERS | |
| 91 | Petechiae | FAERS: 2 | US FAERS | |
| 92 | Poor quality drug administered | FAERS: 2 | US FAERS | |
| 93 | Poor quality sleep | FAERS: 2 | US FAERS | |
| 94 | Prescribed overdose | FAERS: 2 | US FAERS | |
| 95 | Product packaging issue | FAERS: 2 | US FAERS | |
| 96 | Pruritus | FAERS: 2 | US FAERS | |
| 97 | Sinusitis | FAERS: 2 | US FAERS | |
| 98 | Accidental exposure to product | FAERS: 1 | US FAERS | |
| 99 | Acute kidney injury | FAERS: 1 | US FAERS | |
| 100 | Amnesia | FAERS: 1 | US FAERS | |
| 101 | Anaphylactic shock | FAERS: 1 | US FAERS | |
| 102 | Ankle Fracture | FAERS: 1 | US FAERS | |
| 103 | Apparent death | FAERS: 1 | US FAERS | |
| 104 | Arthropod sting | FAERS: 1 | US FAERS | |
| 105 | Ascites | FAERS: 1 | US FAERS | |
| 106 | Atrial Fibrillation | FAERS: 1 | US FAERS | |
| 107 | Autoimmune hepatitis | FAERS: 1 | US FAERS | |
| 108 | Back Pain | FAERS: 1 | US FAERS | |
| 109 | Benign Prostatic Hyperplasia | FAERS: 1 | US FAERS | |
| 110 | Blindness | FAERS: 1 | US FAERS | |
| 111 | Blood urea increased | FAERS: 1 | US FAERS | |
| 112 | Bone pain | FAERS: 1 | US FAERS | |
| 113 | Bronchitis | FAERS: 1 | US FAERS | |
| 114 | Carbohydrate antigen 19-9 increased | FAERS: 1 | US FAERS | |
| 115 | Cerebrovascular accident | FAERS: 1 Canada Vigilance: 1 | Canada Vigilance US FAERS | |
| 116 | Chills | FAERS: 1 | US FAERS | |
| 117 | Colon adenoma | FAERS: 1 | US FAERS | |
| 118 | Contraindicated product prescribed | FAERS: 1 | US FAERS | |
| 119 | Cystitis | FAERS: 1 | US FAERS | |
| 120 | Deafness | FAERS: 1 | US FAERS | |
| 121 | Depressed mood | FAERS: 1 | US FAERS | |
| 122 | Disease risk factor | FAERS: 1 | US FAERS | |
| 123 | Drug effect delayed | FAERS: 1 | US FAERS | |
| 124 | Eczema | FAERS: 1 | US FAERS | |
| 125 | Epigastric discomfort | FAERS: 1 | US FAERS | |
| 126 | Epilepsy | FAERS: 1 | US FAERS | |
| 127 | Eye excision | FAERS: 1 | US FAERS | |
| 128 | Eye inflammation | FAERS: 1 | US FAERS | |
| 129 | Feeling Cold | FAERS: 1 | US FAERS | |
| 130 | Feeling jittery | FAERS: 1 | US FAERS | |
| 131 | Flushing | FAERS: 1 | US FAERS | |
| 132 | Food Poisoning | FAERS: 1 | US FAERS | |
| 133 | Food craving | FAERS: 1 | US FAERS | |
| 134 | Gallbladder pain | FAERS: 1 | US FAERS | |
| 135 | Gastritis | FAERS: 1 | US FAERS | |
| 136 | Gastrointestinal Pain | FAERS: 1 | US FAERS | |
| 137 | Gastrointestinal motility disorder | FAERS: 1 | US FAERS | |
| 138 | General physical health deterioration | FAERS: 1 | US FAERS | |
| 139 | Hepatitis | FAERS: 1 | US FAERS | |
| 140 | Hospice Care | FAERS: 1 | US FAERS | |
| 141 | Hunger | FAERS: 1 | US FAERS | |
| 142 | Hydronephrosis | FAERS: 1 | US FAERS | |
| 143 | Hyperchlorhydria | FAERS: 1 | US FAERS | |
| 144 | Hyperlipasaemia | FAERS: 1 | US FAERS | |
| 145 | Impaired gastric emptying | FAERS: 1 | US FAERS | |
| 146 | Inability to afford medication | FAERS: 1 | US FAERS | |
| 147 | Incorrect product storage | FAERS: 1 | US FAERS | |
| 148 | Infection | FAERS: 1 | US FAERS | |
| 149 | Infectious Mononucleosis | FAERS: 1 | US FAERS | |
| 150 | Inflammation | FAERS: 1 | US FAERS | |
| 151 | Intentional dose omission | FAERS: 1 | US FAERS | |
| 152 | Intercepted drug dispensing error | FAERS: 1 | US FAERS | |
| 153 | Intercepted medication error | FAERS: 1 | US FAERS | |
| 154 | Lethargy | FAERS: 1 | US FAERS | |
| 155 | Limb injury | FAERS: 1 | US FAERS | |
| 156 | Lymphadenitis | FAERS: 1 | US FAERS | |
| 157 | Lymphadenopathy | FAERS: 1 | US FAERS | |
| 158 | Lymphopenia | FAERS: 1 | US FAERS | |
| 159 | Monoplegia | FAERS: 1 | US FAERS | |
| 160 | Musculoskeletal chest pain | FAERS: 1 | US FAERS | |
| 161 | Nephrolithiasis | FAERS: 1 | US FAERS | |
| 162 | Neuralgia | FAERS: 1 | US FAERS | |
| 163 | Neuroglycopenia | FAERS: 1 | US FAERS | |
| 164 | Obesity | FAERS: 1 | US FAERS | |
| 165 | Occupational exposure to product | FAERS: 1 | US FAERS | |
| 166 | Oral pain | FAERS: 1 | US FAERS | |
| 167 | Oropharyngeal discomfort | FAERS: 1 | US FAERS | |
| 168 | Oropharyngeal pain | FAERS: 1 | US FAERS | |
| 169 | Pancreatic enzymes increased | FAERS: 1 | US FAERS | |
| 170 | Pemphigus | FAERS: 1 Canada Vigilance: 1 | Canada Vigilance US FAERS | |
| 171 | Penile swelling | FAERS: 1 | US FAERS | |
| 172 | Pneumonia | FAERS: 1 | US FAERS | |
| 173 | Postoperative wound complication | FAERS: 1 | US FAERS | |
| 174 | Pregnancy | FAERS: 1 | US FAERS | |
| 175 | Prescription drug used without a prescription | FAERS: 1 | US FAERS | |
| 176 | Presyncope | FAERS: 1 | US FAERS | |
| 177 | Product availability issue | FAERS: 1 | US FAERS | |
| 178 | Product complaint | FAERS: 1 | US FAERS | |
| 179 | Product contamination physical | FAERS: 1 | US FAERS | |
| 180 | Product dispensing error | FAERS: 1 | US FAERS | |
| 181 | Product distribution issue | FAERS: 1 | US FAERS | |
| 182 | Product prescribing issue | FAERS: 1 | US FAERS | |
| 183 | Product residue present | FAERS: 1 | US FAERS | |
| 184 | Product shape issue | FAERS: 1 | US FAERS | |
| 185 | Product storage error | FAERS: 1 | US FAERS | |
| 186 | Product supply issue | FAERS: 1 | US FAERS | |
| 187 | Product taste abnormal | FAERS: 1 | US FAERS | |
| 188 | Product use in unapproved indication | FAERS: 1 | US FAERS | |
| 189 | Psoriasis | FAERS: 1 | US FAERS | |
| 190 | Removal of foreign body from gastrointestinal tract | FAERS: 1 | US FAERS | |
| 191 | Respiratory tract congestion | FAERS: 1 | US FAERS | |
| 192 | Retching | FAERS: 1 | US FAERS | |
| 193 | Sensory level normal | FAERS: 1 | US FAERS | |
| 194 | Skin irritation | FAERS: 1 | US FAERS | |
| 195 | Sneezing | FAERS: 1 | US FAERS | |
| 196 | Snoring | FAERS: 1 | US FAERS | |
| 197 | Stress | FAERS: 1 | US FAERS | |
| 198 | Swelling | FAERS: 1 | US FAERS | |
| 199 | Syncope | FAERS: 1 | US FAERS | |
| 200 | Temperature intolerance | FAERS: 1 | US FAERS | |
| 201 | Testicular necrosis | FAERS: 1 | US FAERS | |
| 202 | Therapeutic procedure | FAERS: 1 | US FAERS | |
| 203 | Thirst | FAERS: 1 | US FAERS | |
| 204 | Throat irritation | FAERS: 1 | US FAERS | |
| 205 | Tinea Pedis | FAERS: 1 | US FAERS | |
| 206 | Tinnitus | FAERS: 1 | US FAERS | |
| 207 | Transaminases increased | FAERS: 1 | US FAERS | |
| 208 | Wrong drug administered | FAERS: 1 | US FAERS | |
| 209 | intensive care | FAERS: 1 | US FAERS | |
| 210 | nervous system disorder | FAERS: 1 | US FAERS | |
| 211 | treatment failure | FAERS: 1 | US FAERS | |
| 212 | Choking | Canada Vigilance: 1 | Canada Vigilance | |
| 213 | Colitis | Canada Vigilance: 1 | Canada Vigilance | |
| 214 | Flank Pain | Canada Vigilance: 1 | Canada Vigilance | |
| 215 | Hypersomnia | Canada Vigilance: 1 | Canada Vigilance | |
| 216 | No reaction on previous exposure to drug | Canada Vigilance: 1 | Canada Vigilance | |
| 217 | Product substitution issue | Canada Vigilance: 1 | Canada Vigilance | |
| 218 | Urinary Incontinence | Canada Vigilance: 1 | Canada Vigilance |
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