Cefazolin
(FLKYBGKDCCEQQM-WYUVZMMLSA-M)
Structure
- SMILES
- O=C(N[C@@H]1C(=O)N2[C@@H]1SCC(=C2C(=O)[O-])CSc1nnc(s1)C)Cn1cnnn1.[Na+]
- Molecular Formula:
- C14H13N8NaO4S3
- Molecular Weight:
- 476.489
- Log P:
- -1.6420
- Hydrogen Bond Acceptor:
- 15
- Hydrogen Bond Donor:
- 1
- TPSA:
- 237.76
- CAS Number(s):
- 27164-46-1
Synonym(s)
1.
Cefazolin
2.
Cephazolin
3.
Ancef
4.
Cefamedin
5.
Cefamezine
6.
Cefazolin Sodium
7.
Cephamezine
8.
Cephazolin Sodium
9.
Gramaxin
10.
Kefzol
11.
Sodium Cephazolin
12.
Totacef
13.
Cephazolin, Sodium
14.
Sodium, Cefazolin
15.
Sodium, Cephazolin
External Link(s)
| MeSH | D002437 |
| PubChem Compound | 23675322 102090458 |
| BindingDB | 50247885 |
| ChEBI | 3483 |
| CHEMBL | CHEMBL1200523 |
| KEGG | cpd:C08098 dr:D00905 |
Adverse Drug Event(s)
| Name | Number of Reports | Reference(s) | Data Source | |
|---|---|---|---|---|
| 1 | Pruritus | FAERS: 24 Canada Vigilance: 26 | Canada Vigilance US FAERS | |
| 2 | Nausea | FAERS: 17 Canada Vigilance: 3 | Canada Vigilance US FAERS | |
| 3 | Hypotension | FAERS: 7 Canada Vigilance: 1 | Canada Vigilance US FAERS | |
| 4 | Urticaria | FAERS: 7 Canada Vigilance: 14 | Canada Vigilance US FAERS | |
| 5 | Vomiting | FAERS: 4 Canada Vigilance: 3 | Canada Vigilance US FAERS | |
| 6 | Erythema | FAERS: 3 Canada Vigilance: 7 | Canada Vigilance US FAERS | |
| 7 | Flushing | FAERS: 3 Canada Vigilance: 1 | Canada Vigilance US FAERS | |
| 8 | Hypersensitivity | FAERS: 3 Canada Vigilance: 3 | Canada Vigilance US FAERS | |
| 9 | Post procedural complication | FAERS: 3 | US FAERS | |
| 10 | Wheezing | FAERS: 3 | US FAERS | |
| 11 | Anaphylactic shock | FAERS: 2 | US FAERS | |
| 12 | Chills | FAERS: 2 | US FAERS | |
| 13 | Dizziness | FAERS: 2 Canada Vigilance: 1 | Canada Vigilance US FAERS | |
| 14 | Medication Error | FAERS: 2 | US FAERS | |
| 15 | Rash erythematous | FAERS: 2 Canada Vigilance: 7 | Canada Vigilance US FAERS | |
| 16 | Tachycardia | FAERS: 2 | US FAERS | |
| 17 | Tremor | FAERS: 2 | US FAERS | |
| 18 | Weight decreased | FAERS: 2 | US FAERS | |
| 19 | Abdominal Pain | FAERS: 1 | US FAERS | |
| 20 | Accidental exposure | FAERS: 1 | US FAERS | |
| 21 | Acute kidney injury | FAERS: 1 | US FAERS | |
| 22 | Airway peak pressure increased | FAERS: 1 | US FAERS | |
| 23 | Apallic syndrome | FAERS: 1 | US FAERS | |
| 24 | Ataxia | FAERS: 1 | US FAERS | |
| 25 | Blood alkaline phosphatase increased | FAERS: 1 | US FAERS | |
| 26 | Bradycardia | FAERS: 1 | US FAERS | |
| 27 | Burning sensation | FAERS: 1 | US FAERS | |
| 28 | Cardiac Arrest | FAERS: 1 | US FAERS | |
| 29 | Cardiac Death | FAERS: 1 | US FAERS | |
| 30 | Clostridium difficile colitis | FAERS: 1 | US FAERS | |
| 31 | Dermatomyositis | FAERS: 1 | US FAERS | |
| 32 | Drug prescribing error | FAERS: 1 | US FAERS | |
| 33 | Foaming at mouth | FAERS: 1 | US FAERS | |
| 34 | Hypoxia | FAERS: 1 | US FAERS | |
| 35 | Impaired work ability | FAERS: 1 | US FAERS | |
| 36 | Inappropriate schedule of drug administration | FAERS: 1 | US FAERS | |
| 37 | Infusion site bruising | FAERS: 1 | US FAERS | |
| 38 | Infusion site erythema | FAERS: 1 | US FAERS | |
| 39 | Injection related reaction | FAERS: 1 | US FAERS | |
| 40 | Lip swelling | FAERS: 1 | US FAERS | |
| 41 | Myocardial Infarction | FAERS: 1 | US FAERS | |
| 42 | Neutropenia | FAERS: 1 | US FAERS | |
| 43 | Pancreatitis | FAERS: 1 | US FAERS | |
| 44 | Pharmaceutical product complaint | FAERS: 1 | US FAERS | |
| 45 | Preoperative Care | FAERS: 1 | US FAERS | |
| 46 | Procedural complication | FAERS: 1 | US FAERS | |
| 47 | Respiratory Depression | FAERS: 1 | US FAERS | |
| 48 | Respiratory Failure | FAERS: 1 | US FAERS | |
| 49 | Retching | FAERS: 1 | US FAERS | |
| 50 | Sneezing | FAERS: 1 | US FAERS | |
| 51 | Stridor | FAERS: 1 | US FAERS | |
| 52 | Throat irritation | FAERS: 1 Canada Vigilance: 1 | Canada Vigilance US FAERS | |
| 53 | Transaminases increased | FAERS: 1 | US FAERS | |
| 54 | Unresponsive to stimuli | FAERS: 1 | US FAERS | |
| 55 | White blood cell count decreased | FAERS: 1 | US FAERS | |
| 56 | Wrong drug administered | FAERS: 1 | US FAERS | |
| 57 | Anaphylactoid Reaction | Canada Vigilance: 2 | Canada Vigilance | |
| 58 | Anxiety | Canada Vigilance: 1 | Canada Vigilance | |
| 59 | Asthenia | Canada Vigilance: 2 | Canada Vigilance | |
| 60 | Chest Pain | Canada Vigilance: 2 | Canada Vigilance | |
| 61 | Chest discomfort | Canada Vigilance: 3 | Canada Vigilance | |
| 62 | Cold sweat | Canada Vigilance: 1 | Canada Vigilance | |
| 63 | Colitis | Canada Vigilance: 1 | Canada Vigilance | |
| 64 | Injection Site Reaction | Canada Vigilance: 1 | Canada Vigilance | |
| 65 | Injection site inflammation | Canada Vigilance: 1 | Canada Vigilance | |
| 66 | Injection site pain | Canada Vigilance: 1 | Canada Vigilance | |
| 67 | Laryngospasm | Canada Vigilance: 1 | Canada Vigilance | |
| 68 | Mydriasis | Canada Vigilance: 1 | Canada Vigilance | |
| 69 | Oral mucosal eruption | Canada Vigilance: 1 | Canada Vigilance | |
| 70 | Pain | Canada Vigilance: 3 | Canada Vigilance | |
| 71 | Pallor | Canada Vigilance: 2 | Canada Vigilance | |
| 72 | Purpura | Canada Vigilance: 1 | Canada Vigilance | |
| 73 | Restlessness | Canada Vigilance: 1 | Canada Vigilance | |
| 74 | jaundice | Canada Vigilance: 1 | Canada Vigilance |
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