MetaADEDB 2.0 @ LMMD
delafloxacin
(DYDCPNMLZGFQTM-UHFFFAOYSA-N)
Structure
SMILES
OC1CN(C1)c1c(F)cc2c(c1Cl)n(cc(c2=O)C(=O)O)c1nc(N)c(cc1F)F
Type(s)
Approved; Investigational
ATC code(s)
J01MA23
Molecular Formula:
C18H12ClF3N4O4
Molecular Weight:
440.760
Log P:
2.5639
Hydrogen Bond Acceptor:
8
Hydrogen Bond Donor:
3
TPSA:
121.68
CAS Number(s):
189279-58-1
Synonym(s)
1.
delafloxacin
2.
1-(6-amino-3,5-difluoropyridin-2-yl)-8-chloro-6-fluoro-7-(3-hydroxyazetidin-1-yl)-4-oxo-1,4-dihydroquinoline-3-carboxylic acid
3.
ABT 492
4.
ABT-492
5.
ABT492
6.
RX-3341
External Link(s)
MeSHC477891
PubChem Compound487101
CHEMBLCHEMBL2105637
DrugBankDB11943
DrugCentral5238
KEGGdr:D09330
Therapeutic Target DatabaseD0V9BU
ZINC3827556
Adverse Drug Event(s)
NameNumber of ReportsReference(s)Data Source
1ArthralgiaFAERS: 3US FAERS
2NauseaFAERS: 3US FAERS
3Product use in unapproved indicationFAERS: 3US FAERS
4FatigueFAERS: 2US FAERS
5NervousnessFAERS: 2US FAERS
6AgitationFAERS: 1US FAERS
7Anaphylactic shockFAERS: 1US FAERS
8AnxietyFAERS: 1US FAERS
9Back PainFAERS: 1US FAERS
10Clostridium difficile colitisFAERS: 1US FAERS
11Drug administered to patient of inappropriate ageFAERS: 1US FAERS
12Drug prescribing errorFAERS: 1US FAERS
13Electrolyte imbalanceFAERS: 1US FAERS
14HeadacheFAERS: 1US FAERS
15HypersensitivityFAERS: 1US FAERS
16Inappropriate schedule of product administrationFAERS: 1US FAERS
17LeukopeniaFAERS: 1US FAERS
18Lip swellingFAERS: 1US FAERS
19MalaiseFAERS: 1US FAERS
20Muscle tightnessFAERS: 1US FAERS
21MyalgiaFAERS: 1US FAERS
22Overgrowth fungalFAERS: 1US FAERS
23ParanoiaFAERS: 1US FAERS
24PruritusFAERS: 1US FAERS
25Renal painFAERS: 1US FAERS
26SomnolenceFAERS: 1US FAERS
27ThrombocytopeniaFAERS: 1US FAERS
28ToothacheFAERS: 1US FAERS
29UrticariaFAERS: 1US FAERS
30VomitingFAERS: 1US FAERS
31Community-Acquired Infections28598693CTD
32Pneumonia, Bacterial28598693CTD
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