MetaADEDB 2.0 @ LMMD
Dronedarone hydrochloride
(DWKVCQXJYURSIQ-UHFFFAOYSA-N)
Structure
SMILES
CCCCc1oc2c(c1C(=O)c1ccc(cc1)OCCCN(CCCC)CCCC)cc(cc2)NS(=O)(=O)C.Cl
Molecular Formula:
C31H45ClN2O5S
Molecular Weight:
593.217
Log P:
9.0048
Hydrogen Bond Acceptor:
7
Hydrogen Bond Donor:
2
TPSA:
97.23
CAS Number(s):
141625-93-6
Synonym(s)
1.
Dronedarone hydrochloride
2.
N-[2-Butyl-3-[4-[3-(dibutylamino)propoxy]benzoyl]-1-benzofuran-5-yl]methanesulfonamide;hydron;chloride
External Link(s)
PubChem Compound219025
46863909
CHEMBLCHEMBL1201729
KEGGdr:D03914
Adverse Drug Event(s)
NameNumber of ReportsReference(s)Data Source
1DizzinessFAERS: 6US FAERS
2Alanine Aminotransferase IncreasedFAERS: 5US FAERS
3Aspartate Aminotransferase IncreasedFAERS: 5US FAERS
4Atrial FibrillationFAERS: 5US FAERS
5Blood creatinine increasedFAERS: 5US FAERS
6NauseaFAERS: 5US FAERS
7FatigueFAERS: 4US FAERS
8Pulmonary toxicityFAERS: 4US FAERS
9Abdominal discomfortFAERS: 3US FAERS
10Acute polyneuropathyFAERS: 3US FAERS
11PalpitationsFAERS: 3US FAERS
12PneumonitisFAERS: 3US FAERS
13Respiratory FailureFAERS: 3US FAERS
14SyncopeFAERS: 3US FAERS
15VomitingFAERS: 3US FAERS
16Abdominal PainFAERS: 2US FAERS
17AstheniaFAERS: 2US FAERS
18Chest discomfortFAERS: 2US FAERS
19HeadacheFAERS: 2US FAERS
20HypotensionFAERS: 2US FAERS
21MyalgiaFAERS: 2US FAERS
22Pulmonary FibrosisFAERS: 2US FAERS
23Rash erythematousFAERS: 2US FAERS
24RhabdomyolysisFAERS: 2US FAERS
25WheezingFAERS: 2US FAERS
26Abdominal tendernessFAERS: 1US FAERS
27AgranulocytosisFAERS: 1US FAERS
28Alanine aminotransferase abnormalFAERS: 1US FAERS
29AsthmaFAERS: 1US FAERS
30AtelectasisFAERS: 1US FAERS
31Back PainFAERS: 1US FAERS
32BedriddenFAERS: 1US FAERS
33Blood urea increasedFAERS: 1US FAERS
34BradycardiaFAERS: 1US FAERS
35Brain natriuretic peptide increasedFAERS: 1US FAERS
36Cardiac ArrestFAERS: 1US FAERS
37Cardioactive drug level increasedFAERS: 1US FAERS
38CellulitisFAERS: 1US FAERS
39ChillsFAERS: 1US FAERS
40Creatinine renal clearance increasedFAERS: 1US FAERS
41DehydrationFAERS: 1US FAERS
42Diffuse alveolar damageFAERS: 1US FAERS
43Drug ineffectiveFAERS: 1US FAERS
44DyspepsiaFAERS: 1US FAERS
45EosinophiliaFAERS: 1US FAERS
46HypoxiaFAERS: 1US FAERS
47Increased upper airway secretionFAERS: 1US FAERS
48InfarctionFAERS: 1US FAERS
49Joint swellingFAERS: 1US FAERS
50LethargyFAERS: 1US FAERS
51MalaiseFAERS: 1US FAERS
52PancreatitisFAERS: 1US FAERS
53PneumoniaFAERS: 1US FAERS
54PresyncopeFAERS: 1US FAERS
55PurpuraFAERS: 1US FAERS
56RegurgitationFAERS: 1US FAERS
57Right ventricular failureFAERS: 1US FAERS
58Sudden Cardiac DeathFAERS: 1US FAERS
59Toxicity to various agentsFAERS: 1US FAERS
60Urinary tract infectionFAERS: 1US FAERS
61UrticariaFAERS: 1US FAERS
62VertigoFAERS: 1US FAERS
63Weight decreasedFAERS: 1US FAERS
64treatment failureFAERS: 1US FAERS
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