Trifluoperazine
(BXDAOUXDMHXPDI-UHFFFAOYSA-N)
Structure
- SMILES
- CN1CCN(CC1)CCCN1c2ccccc2Sc2c1cc(cc2)C(F)(F)F.Cl.Cl
- Molecular Formula:
- C21H26Cl2F3N3S
- Molecular Weight:
- 480.417
- Log P:
- 6.4904
- Hydrogen Bond Acceptor:
- 3
- Hydrogen Bond Donor:
- 2
- TPSA:
- 35.02
- CAS Number(s):
- 440-17-5
Synonym(s)
1.
Trifluoperazine
2.
Trifluoroperazine
3.
Triftazin
4.
Apo-Trifluoperazine
5.
Eskazine
6.
Flupazine
7.
Stelazine
8.
Terfluzine
9.
Trifluoperazine HCL
10.
Trifluoperazine Hydrochloride
11.
Trifluperazine
12.
Apo Trifluoperazine
13.
ApoTrifluoperazine
External Link(s)
Adverse Drug Event(s)
| Name | Number of Reports | Reference(s) | Data Source | |
|---|---|---|---|---|
| 1 | Asthenia | FAERS: 3 Canada Vigilance: 5 | Canada Vigilance US FAERS | |
| 2 | Headache | FAERS: 3 Canada Vigilance: 1 | Canada Vigilance US FAERS | |
| 3 | Medication Error | FAERS: 3 | US FAERS | |
| 4 | Drug dispensing error | FAERS: 2 | US FAERS | |
| 5 | Drug ineffective | FAERS: 2 | US FAERS | |
| 6 | Incorrect dose administered | FAERS: 2 | US FAERS | |
| 7 | Malaise | FAERS: 2 | US FAERS | |
| 8 | Myocardial Infarction | FAERS: 2 Canada Vigilance: 1 | Canada Vigilance US FAERS | |
| 9 | Abdominal discomfort | FAERS: 1 | US FAERS | |
| 10 | Adverse event | FAERS: 1 | US FAERS | |
| 11 | Agitation | FAERS: 1 Canada Vigilance: 7 | Canada Vigilance US FAERS | |
| 12 | Angioplasty | FAERS: 1 | US FAERS | |
| 13 | Anxiety | FAERS: 1 Canada Vigilance: 2 | Canada Vigilance US FAERS | |
| 14 | Arthralgia | FAERS: 1 | US FAERS | |
| 15 | Blepharospasm | FAERS: 1 | US FAERS | |
| 16 | Cerebrovascular accident | FAERS: 1 | US FAERS | |
| 17 | Chest Pain | FAERS: 1 | US FAERS | |
| 18 | Cold sweat | FAERS: 1 | US FAERS | |
| 19 | Drug exposure during pregnancy | FAERS: 1 | US FAERS | |
| 20 | Drug withdrawal syndrome | FAERS: 1 | US FAERS | |
| 21 | Dry skin | FAERS: 1 | US FAERS | |
| 22 | Fatigue | FAERS: 1 Canada Vigilance: 1 | Canada Vigilance US FAERS | |
| 23 | Feeling abnormal | FAERS: 1 | US FAERS | |
| 24 | Incorrect product administration duration | FAERS: 1 | US FAERS | |
| 25 | Intercepted drug dispensing error | FAERS: 1 | US FAERS | |
| 26 | Lip swelling | FAERS: 1 | US FAERS | |
| 27 | Myalgia | FAERS: 1 Canada Vigilance: 3 | Canada Vigilance US FAERS | |
| 28 | Nausea | FAERS: 1 Canada Vigilance: 4 | Canada Vigilance US FAERS | |
| 29 | Product availability issue | FAERS: 1 | US FAERS | |
| 30 | Product use in unapproved indication | FAERS: 1 | US FAERS | |
| 31 | Stress | FAERS: 1 | US FAERS | |
| 32 | Abdominal Pain | Canada Vigilance: 1 | Canada Vigilance | |
| 33 | Accidental overdose | Canada Vigilance: 1 | Canada Vigilance | |
| 34 | Adjustment disorder with depressed mood | Canada Vigilance: 1 | Canada Vigilance | |
| 35 | Agranulocytosis | Canada Vigilance: 2 | Canada Vigilance | |
| 36 | Akathisia | Canada Vigilance: 18 | Canada Vigilance | |
| 37 | Akinesia | Canada Vigilance: 2 | Canada Vigilance | |
| 38 | Alpha-2 macroglobulin increased | Canada Vigilance: 1 | Canada Vigilance | |
| 39 | Angioedema | Canada Vigilance: 3 | Canada Vigilance | |
| 40 | Apathy | Canada Vigilance: 4 | Canada Vigilance | |
| 41 | Ataxia | Canada Vigilance: 4 | Canada Vigilance | |
| 42 | Catatonia | Canada Vigilance: 2 | Canada Vigilance | |
| 43 | Cerebral Palsy | Canada Vigilance: 1 | Canada Vigilance | |
| 44 | Chest discomfort | Canada Vigilance: 1 | Canada Vigilance | |
| 45 | Choking | Canada Vigilance: 1 | Canada Vigilance | |
| 46 | Cogwheel Rigidity | Canada Vigilance: 1 | Canada Vigilance | |
| 47 | Constipation | Canada Vigilance: 4 | Canada Vigilance | |
| 48 | Conversion disorder | Canada Vigilance: 1 | Canada Vigilance | |
| 49 | Cyanosis | Canada Vigilance: 1 | Canada Vigilance | |
| 50 | Dermatitis | Canada Vigilance: 1 | Canada Vigilance | |
| 51 | Dizziness | Canada Vigilance: 6 | Canada Vigilance | |
| 52 | Dysarthria | Canada Vigilance: 6 | Canada Vigilance | |
| 53 | Dysphonia | Canada Vigilance: 3 | Canada Vigilance | |
| 54 | Dystonia | Canada Vigilance: 16 | Canada Vigilance | |
| 55 | Emotional disorder | Canada Vigilance: 1 | Canada Vigilance | |
| 56 | Emotional distress | Canada Vigilance: 1 | Canada Vigilance | |
| 57 | Epilepsy | Canada Vigilance: 1 | Canada Vigilance | |
| 58 | Erectile dysfunction | Canada Vigilance: 1 | Canada Vigilance | |
| 59 | Erythema | Canada Vigilance: 2 | Canada Vigilance | |
| 60 | Facial paralysis | Canada Vigilance: 2 | Canada Vigilance | |
| 61 | Feeling jittery | Canada Vigilance: 2 | Canada Vigilance | |
| 62 | Flushing | Canada Vigilance: 1 | Canada Vigilance | |
| 63 | Gastritis | Canada Vigilance: 1 | Canada Vigilance | |
| 64 | Glossitis | Canada Vigilance: 2 | Canada Vigilance | |
| 65 | Hepatitis | Canada Vigilance: 1 | Canada Vigilance | |
| 66 | Hyperkinesia | Canada Vigilance: 1 | Canada Vigilance | |
| 67 | Hypersensitivity | Canada Vigilance: 1 | Canada Vigilance | |
| 68 | Hypotension | Canada Vigilance: 2 | Canada Vigilance | |
| 69 | Joint stiffness | Canada Vigilance: 2 | Canada Vigilance | |
| 70 | Lethargy | Canada Vigilance: 3 | Canada Vigilance | |
| 71 | Leukopenia | Canada Vigilance: 2 | Canada Vigilance | |
| 72 | Muscle Rigidity | Canada Vigilance: 10 | Canada Vigilance | |
| 73 | Muscle Spasticity | Canada Vigilance: 2 | Canada Vigilance | |
| 74 | Muscle tightness | Canada Vigilance: 2 | Canada Vigilance | |
| 75 | Musculoskeletal Pain | Canada Vigilance: 1 | Canada Vigilance | |
| 76 | Musculoskeletal stiffness | Canada Vigilance: 3 | Canada Vigilance | |
| 77 | Mydriasis | Canada Vigilance: 1 | Canada Vigilance | |
| 78 | Neck Pain | Canada Vigilance: 1 | Canada Vigilance | |
| 79 | Nervousness | Canada Vigilance: 2 | Canada Vigilance | |
| 80 | Nystagmus | Canada Vigilance: 2 | Canada Vigilance | |
| 81 | Oculogyric crisis | Canada Vigilance: 6 | Canada Vigilance | |
| 82 | Opisthotonus | Canada Vigilance: 9 | Canada Vigilance | |
| 83 | Pain | Canada Vigilance: 1 | Canada Vigilance | |
| 84 | Pallor | Canada Vigilance: 2 | Canada Vigilance | |
| 85 | Pancytopenia | Canada Vigilance: 1 | Canada Vigilance | |
| 86 | Pruritus | Canada Vigilance: 1 | Canada Vigilance | |
| 87 | Rash erythematous | Canada Vigilance: 1 | Canada Vigilance | |
| 88 | Reduced facial expression | Canada Vigilance: 5 | Canada Vigilance | |
| 89 | Respiratory Depression | Canada Vigilance: 1 | Canada Vigilance | |
| 90 | Restlessness | Canada Vigilance: 1 | Canada Vigilance | |
| 91 | Somnolence | Canada Vigilance: 17 | Canada Vigilance | |
| 92 | Tachycardia | Canada Vigilance: 2 | Canada Vigilance | |
| 93 | Tardive Dyskinesia | Canada Vigilance: 2 | Canada Vigilance | |
| 94 | Tension | Canada Vigilance: 1 | Canada Vigilance | |
| 95 | Tetany | Canada Vigilance: 2 | Canada Vigilance | |
| 96 | Tinnitus | Canada Vigilance: 2 | Canada Vigilance | |
| 97 | Tongue movement disturbance | Canada Vigilance: 1 | Canada Vigilance | |
| 98 | Tongue spasm | Canada Vigilance: 1 | Canada Vigilance | |
| 99 | Torticollis | Canada Vigilance: 12 | Canada Vigilance | |
| 100 | Tremor | Canada Vigilance: 37 | Canada Vigilance | |
| 101 | Trismus | Canada Vigilance: 12 | Canada Vigilance | |
| 102 | Urinary Incontinence | Canada Vigilance: 1 | Canada Vigilance | |
| 103 | Urinary Retention | Canada Vigilance: 2 | Canada Vigilance | |
| 104 | Vertigo | Canada Vigilance: 1 | Canada Vigilance | |
| 105 | Vomiting | Canada Vigilance: 1 | Canada Vigilance | |
| 106 | jaundice | Canada Vigilance: 3 | Canada Vigilance |
Powered by :
Page last updated at 2020-05-25 10:01:57 (Asia/Shanghai) | You are visitor No. 120234
Copyright © 2019-2020 Laboratory of Molecular Modeling and Design, Shanghai Key Laboratory of New Drug Design, School of Pharmacy, East China University of Science and Technology. All rights reserved.