MetaADEDB 2.0 @ LMMD
esmolol
(AQNDDEOPVVGCPG-UHFFFAOYSA-N)
Structure
SMILES
COC(=O)CCc1ccc(cc1)OCC(CNC(C)C)O
Type(s)
Approved
ATC code(s)
C07AB09
Molecular Formula:
C16H25NO4
Molecular Weight:
295.374
Log P:
1.9208
Hydrogen Bond Acceptor:
5
Hydrogen Bond Donor:
2
TPSA:
67.79
CAS Number(s):
81147-92-4; 103598-03-4
Synonym(s)
1.
esmolol
2.
ASL 8052
3.
ASL-8052
4.
Brevibloc
5.
esmolol hydrochloride
External Link(s)
MeSHC036604
PubChem Compound59768
BindingDB50404796
ChEBI88206
CHEMBLCHEMBL768
DrugBankDB00187
DrugCentral1054
IUPHAR/BPS Guide to PHARMACOLOGY7178
KEGGdr:D07916
cpd:C06980
Therapeutic Target DatabaseD03XTC
Adverse Drug Event(s)
NameNumber of ReportsReference(s)Data Source
1treatment failureFAERS: 2US FAERS
2Drug ineffectiveFAERS: 1US FAERS
3False positive investigation resultFAERS: 1US FAERS
4Laboratory test interferenceFAERS: 1US FAERS
5Abdominal discomfortSIDER
6Abnormal visionSIDER
7Acute Coronary SyndromeSIDER
8AgitationSIDER
9Angina PectorisSIDER
10AngioedemaSIDER
11AnorexiaSIDER
12AnxietySIDER
13AstheniaSIDER
14AtelectasisSIDER
15Atrioventricular BlockSIDER
16Bradycardia14653084
17587605		CTD
SIDER
17BronchospasmSIDER
18Cardiac ArrestSIDER
19Chest PainSIDER
20ChillsSIDER
21Cold sweatSIDER
22Common ColdSIDER
23ConstipationSIDER
24DizzinessSIDER
25DrowsinessSIDER
26DysgeusiaSIDER
27DyspepsiaSIDER
28DysuriaSIDER
29EcchymosisSIDER
30Electrocardiogram abnormalSIDER
31ErythemaSIDER
32ExtravasationSIDER
33FatigueSIDER
34Feeling abnormalSIDER
35FlushingSIDER
36HeadacheSIDER
37Hypertensive crisisSIDER
38Hypotension asymptomaticSIDER
39Hypotension symptomaticSIDER
40Hypotension

View details

1352091
2870082
2900259
7614641
8102224
9080239
12492801
16879470
18214007
19681422
 		CTD
SIDER
41IndurationSIDER
42InflammationSIDER
43LightheadednessSIDER
44Myocardial InfarctionSIDER
45Myocardial Ischemia2900259CTD
46NasopharyngitisSIDER
47Nausea11159231CTD
SIDER
48NeuropathySIDER
49Oliguria2900259CTD
SIDER
50Pain, Postoperative1683182CTD
51PainSIDER
52PallorSIDER
53PharyngitisSIDER
54Pleuritic painSIDER
55PneumothoraxSIDER
56Postoperative Complications9576226CTD
57PruritusSIDER
58PsoriasisSIDER
59RalesSIDER
60Renal tubular necrosisSIDER
61Respiratory FailureSIDER
62RhinitisSIDER
63RhonchiSIDER
64ShockSIDER
65Skin necrosisSIDER
66SomnolenceSIDER
67Substance Withdrawal Syndrome2569849CTD
68Syncope8985804CTD
SIDER
69Tachycardia

View details

7617516
9466032
10756546
16143579
 		CTD
70ThrombophlebitisSIDER
71Urinary RetentionSIDER
72UrticariaSIDER
73Ventricular FibrillationSIDER
74Visual ImpairmentSIDER
75Vomiting11159231CTD
SIDER
76WheezingSIDER
77nervous system disorderSIDER
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