MetaADEDB 2.0 @ LMMD
Amphotericin B
(APKFDSVGJQXUKY-UPWJBAEMSA-N)
Structure
SMILES
O[C@@H]1CC[C@@H](O)[C@H](O)C[C@H](O)C[C@]2(O)C[C@H](O)[C@H]([C@@H](O2)C[C@H](/C=C/C=C/C=C/C=C/C=C/C=C/C=C/[C@@H]([C@H]([C@H]([C@@H](OC(=O)C[C@@H](C1)O)C)C)O)C)OC1OC(C)C(C(C1O)N)O)C(=O)O
Molecular Formula:
C47H73NO17
Molecular Weight:
924.079
Log P:
1.4120
Hydrogen Bond Acceptor:
18
Hydrogen Bond Donor:
12
TPSA:
319.61
CAS Number(s):
1397-89-3
Synonym(s)
1.
Amphotericin B
2.
Amphocil
3.
Amphotericin
4.
Amphotericin B Cholesterol Dispersion
5.
Amphotericin B Colloidal Dispersion
6.
Fungizone
External Link(s)
MeSHD000666
PubChem Compound5386092
CHEMBLCHEMBL364143
Adverse Drug Event(s)
NameNumber of ReportsReference(s)Data Source
1Acute myocardial infarctionFAERS: 3US FAERS
2OverdoseFAERS: 3US FAERS
3Accidental overdoseFAERS: 2US FAERS
4Catheter related infectionFAERS: 2US FAERS
5Chest PainFAERS: 2US FAERS
6Drug administration errorFAERS: 2US FAERS
7Medication ErrorFAERS: 2US FAERS
8Ventricular FibrillationFAERS: 2US FAERS
9Anaphylactic shockFAERS: 1US FAERS
10AngioedemaFAERS: 1US FAERS
11AnuriaFAERS: 1US FAERS
12BronchospasmFAERS: 1US FAERS
13CataractFAERS: 1US FAERS
14ChillsFAERS: 1US FAERS
15CholecystitisFAERS: 1US FAERS
16Hepatic necrosisFAERS: 1US FAERS
17HypotensionFAERS: 1US FAERS
18HypoxiaFAERS: 1US FAERS
19Lung AbscessFAERS: 1US FAERS
20MalaiseFAERS: 1US FAERS
21Respiratory distressFAERS: 1US FAERS
22TremorFAERS: 1US FAERS
23White blood cell count decreasedFAERS: 1US FAERS
24ZygomycosisFAERS: 1US FAERS
25InfectionCanada Vigilance: 1Canada Vigilance
26Respiratory FailureCanada Vigilance: 1Canada Vigilance
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