MetaADEDB 2.0 @ LMMD
rebamipide
(ALLWOAVDORUJLA-UHFFFAOYSA-N)
Structure
SMILES
Clc1ccc(cc1)C(=O)NC(C(=O)O)Cc1cc(=O)[nH]c2c1cccc2
Type(s)
Investigational
ATC code(s)
A02BX14
Molecular Formula:
C19H15ClN2O4
Molecular Weight:
370.786
Log P:
2.9981
Hydrogen Bond Acceptor:
5
Hydrogen Bond Donor:
3
TPSA:
99.26
CAS Number(s):
90098-04-7; 111911-87-6; 139344-42-6
Synonym(s)
1.
rebamipide
2.
2-(4-chlorobenzoylamino)-3-(2(1H)-quinolinon-4-yl)propionic acid
3.
OPC 12759
4.
OPC-12759
5.
rebamipide, (+)-isomer
6.
rebamipide, (-)-isomer
External Link(s)
MeSHC052785
PubChem Compound5042
ChEBI93814
CHEMBLCHEMBL1697771
DrugBankDB11656
DrugCentral2360
IUPHAR/BPS Guide to PHARMACOLOGY871
KEGGdr:D01121
Therapeutic Target DatabaseD03BQP
Adverse Drug Event(s)
NameNumber of ReportsReference(s)Data Source
1AcneOFFSIDES
2Acute respiratory failureOFFSIDES
3Alanine Aminotransferase IncreasedOFFSIDES
4Altered state of consciousnessOFFSIDES
5AnorexiaOFFSIDES
6Anti-insulin antibody positiveOFFSIDES
7Antithrombin III decreasedOFFSIDES
8ApathyOFFSIDES
9AppendicitisOFFSIDES
10AscitesOFFSIDES
11AsterixisOFFSIDES
12AuraOFFSIDES
13BasophiliaOFFSIDES
14Beta 2 microglobulin urine increasedOFFSIDES
15Beta-N-acetyl-D-glucosaminidase increasedOFFSIDES
16Bile duct cancer stage IIIOFFSIDES
17Blood albumin decreasedOFFSIDES
18Blood alkaline phosphatase increasedOFFSIDES
19Blood creatine phosphokinase decreasedOFFSIDES
20Blood creatine phosphokinase increasedOFFSIDES
21Blood creatinine increasedOFFSIDES
22Blood glucose decreasedOFFSIDES
23Blood lactate dehydrogenase decreasedOFFSIDES
24Blood lactate dehydrogenase increasedOFFSIDES
25Blood sodium abnormalOFFSIDES
26Blood sodium increasedOFFSIDES
27Blood sodiumOFFSIDES
28Blood urea abnormalOFFSIDES
29Blood urea increasedOFFSIDES
30Blood uric acidOFFSIDES
31Body TemperatureOFFSIDES
32Bone marrow depressionOFFSIDES
33Brain AbscessOFFSIDES
34CYTOMEGALOVIRUS ANTIGENOFFSIDES
35Cell marker increasedOFFSIDES
36Cerebral disorderOFFSIDES
37Cervical myelopathyOFFSIDES
38CholangiolitisOFFSIDES
39Choroidal dystrophyOFFSIDES
40Cold sweatOFFSIDES
41Colonic fistulaOFFSIDES
42Concomitant disease aggravatedOFFSIDES
43Concomitant disease progressionOFFSIDES
44Coronary angioplastyOFFSIDES
45CraniotomyOFFSIDES
46Cystitis viralOFFSIDES
47Cytomegalovirus test positiveOFFSIDES
48Depressed Level of ConsciousnessOFFSIDES
49DermatomyositisOFFSIDES
50Diabetic NephropathyOFFSIDES
51Disseminated Intravascular CoagulationOFFSIDES
52DizzinessOFFSIDES
53Duodenal fistulaOFFSIDES
54DyslaliaOFFSIDES
55EczemaOFFSIDES
56EncephalitisOFFSIDES
57EndophthalmitisOFFSIDES
58EnterocolitisOFFSIDES
59EpiglottitisOFFSIDES
60Erythema MultiformeOFFSIDES
61Failure to anastomoseOFFSIDES
62Fatty LiverOFFSIDES
63Gamma-Glutamyltransferase IncreasedOFFSIDES
64Gastric ileusOFFSIDES
65GlossitisOFFSIDES
66Granulocyte count decreasedOFFSIDES
67Helicobacter pylori identification test positiveOFFSIDES
68Hepatitis BOFFSIDES
69HepatosplenomegalyOFFSIDES
70HiccoughOFFSIDES
71Histiocytosis haematophagicOFFSIDES
72HydropneumothoraxOFFSIDES
73Infected epidermal cystOFFSIDES
74Infusion site painOFFSIDES
75Infusion site swellingOFFSIDES
76Injection site cellulitisOFFSIDES
77Intestinal Diseases11686837CTD
78Kidney NeoplasmOFFSIDES
79Klebsiella sepsisOFFSIDES
80Left Ventricular HypertrophyOFFSIDES
81Leukopenia neonatalOFFSIDES
82Lip erosionOFFSIDES
83Lymph node palpableOFFSIDES
84Lymphangiosis carcinomatosaOFFSIDES
85Lymphocyte stimulation test positiveOFFSIDES
86Malignant neoplasm progressionOFFSIDES
87Maximal Voluntary VentilationOFFSIDES
88Muscle WeaknessOFFSIDES
89Musculoskeletal stiffnessOFFSIDES
90Neutrophil count decreasedOFFSIDES
91Nutritional condition abnormalOFFSIDES
92Oculomucocutaneous syndromeOFFSIDES
93Optic Disc EdemaOFFSIDES
94Optic NeuritisOFFSIDES
95Oropharyngeal discomfortOFFSIDES
96OsteomyelitisOFFSIDES
97PallorOFFSIDES
98Pancreatic CystOFFSIDES
99Pancreatic duct obstructionOFFSIDES
100PericarditisOFFSIDES
101PeritonitisOFFSIDES
102PeritonsillitisOFFSIDES
103Personality ChangeOFFSIDES
104Pharyngolaryngeal PainOFFSIDES
105PneumothoraxOFFSIDES
106Polyomavirus-associated nephropathyOFFSIDES
107Postoperative wound complicationOFFSIDES
108Primary sequestrumOFFSIDES
109Protein total decreasedOFFSIDES
110Psychiatric symptomOFFSIDES
111Pulmonary EosinophiliaOFFSIDES
112Purulent dischargeOFFSIDES
113PyelonephritisOFFSIDES
114Salmonella sepsisOFFSIDES
115SequestrectomyOFFSIDES
116Shunt malfunctionOFFSIDES
117Sick Sinus SyndromeOFFSIDES
118Sinoatrial BlockOFFSIDES
119Stevens-Johnson SyndromeOFFSIDES
120Stomach Diseases16184426CTD
121Stomach Neoplasms15993841CTD
122Stomatitis29054700CTD
123Suture related complicationOFFSIDES
124Therapy non-responderOFFSIDES
125Thrombin-antithrombin III complex decreasedOFFSIDES
126TineaOFFSIDES
127Upper respiratory tract inflammationOFFSIDES
128VIIth nerve paralysisOFFSIDES
129Vocal Cord ParalysisOFFSIDES
130Wound ComplicationOFFSIDES
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